Identifying key signatures of high productivity from transcr

Identifying key signatures of high productivity from transcriptome and proteome profiles of CHO cells

... produced from these cells (Anderson and Krummen, 2002; Chu and Robinson, 2001) To meet market demands, the scale of bio-therapeutic production is usually very large, often in tens of thousands of litres, ... plausible that the gene and protein expression profile of a highly productive cell line holds the key signature for high productivity, we used combined transcripto...

Ngày tải lên : 09/10/2015, 11:06

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Báo cáo Y học: Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding pot

... modiﬁcations on heparin binding, recombinant CHO cells were treated with inhibitors of tyrosine sulfation and N-glycosylation under conditions that allowed partial inhibition of these modiﬁcations ... In summary, we present evidence for a very strong similarity of HCII from human serum and its recombinant counterpart from CHO cells with respect to tyrosine...

Ngày tải lên : 08/03/2014, 22:20

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Báo cáo y học: "Molecular signature of hypersaline adaptation: insights from genome and proteome composition of halophilic prokaryote" ppt

... extensive and systematic analysis of the genome and proteome composition of halophilic organisms, along with a comparative study of non-halophiles, with a view to characterize the molecular signatures ... and frequency distribution of genes on hydrophobicity and pI COA on amino acid usage and frequency distribution of genes on hydrophobicity and pI (a) Positions...

Ngày tải lên : 14/08/2014, 08:21

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Tài liệu Báo cáo khoa học: "Mining User Reviews: from Speciﬁcation to Summarization Xinfan Meng Key Laboratory of Computational Linguistics " doc

... and Adam Pauls 2006a Multi-Document Summarization of Evaluative Text In Proceedings of the conference of the European Chapter of the Association for Computational Linguistics Giuseppe Carenini, ... to combine multiple speciﬁcations to include all possible features Clustering algorithm can be used to combine speciﬁcations We propose an approach that takes following inherent...

Ngày tải lên : 20/02/2014, 09:20

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Báo cáo khoa học: Studies on structure–function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway ppt

... ensure the generation of the ketone The ability of ScPDC and ZmPDC to decarboxylate indolepyruvate was examined under the same conditions In the case of ZmPDC maximum enzyme concentration was 2.3 ... independent of the concentration of the auxiliary enzyme, conﬁrming that the coupled assay monitors the true rate of EcIPDC catalysis Figs and and Table illustr...

Ngày tải lên : 08/03/2014, 02:20

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Báo cáo khoa học: Novel a-conotoxins from Conus spurius and the a-conotoxin EI share high-afﬁnity potentiation and low-afﬁnity inhibition of nicotinic acetylcholine receptors doc

... determination and cloning of the cDNA encoding two novel peptides, SrIA and SrIB, found in the venom of Conus spurius The pattern and the spacing of their cysteines indicate that they belong to the a-Conotoxins ... In the present article, we have deﬁned the weak antagonist properties of the novel C spurius a-conotoxins, and of a synthetic analog...

Ngày tải lên : 16/03/2014, 11:20

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Báo cáo khóa học: Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations pptx

... complex from carbonatewashed membranes of SY5Y and 5-day-old mouse brain were examined using 10% Tris/tricine gels with reducing Ó FEBS 2003 Analysis of mouse and human brain presenilin complex ... assembly and stabilization of the complex [50–52] High levels of PS complex were detected in mouse embryonic brain consistent with high expres...

Ngày tải lên : 16/03/2014, 16:20

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báo cáo hóa học:" Neuronal transcription factor Brn-3a(l) is over expressed in high-grade ovarian carcinomas and tumor cells from ascites of patients with advanced-stage ovarian cancer" ppt

... Cite this article as: Ahmed et al.: Neuronal transcription factor Brn-3a(l) is over expressed in high-grade ovarian carcinomas and tumor cells from ascites of patients with advanced-stage ovarian ... pattern of Brn-3a(l) in primary tumors, ascites tumor cells and ovarian cancer cell lines consistent with novel distinct role of this...

Ngày tải lên : 20/06/2014, 07:20

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Báo cáo lâm nghiệp:" The key-role of topsoil moisture on CO2 efflux from a Mediterranean Quercus ilex forest" docx

... Several data are available on the respiration of Mediterranean ecosystems Most of them were measured in the Mediterranean Basin [4, 5, 10, 15, 26, 32, 37, 38] Some other data dealing with Australian ... that the increase of temperature has a greater impact on the global respiration of the ecosystem Topsoil moisture and CO2 efflux than on primary productio...

Ngày tải lên : 08/08/2014, 01:21

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Báo cáo y học: "Diagnostic accuracy of existing methods for identifying diabetic foot ulcers from inpatient and outpatient datasets" pptx

... et al.: Diagnostic accuracy of existing methods for identifying diabetic foot ulcers from inpatient and outpatient datasets Journal of Foot and Ankle Research 2010 3:27 Submit your next manuscript ... of Foot and Ankle Research 2010, 3:27 http://www.jfootankleres.com/content/3/1/27 Page of Table Comparison of methods for diagnostic accuracy of...

Ngày tải lên : 10/08/2014, 21:24

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báo cáo khoa học: " Isolation and functional characterization of cold-regulated promoters, by digitally identifying peach fruit cold-induced genes from a large EST dataset" pptx

... gAgTTggATgggTCCTCTgC CCAAACCAAAgCCAgTTTCATTCA CCAggTTTTgTATgAgTgCCgTA ACCTTggCCATCCTCTTCTT AgAAATCTTgACCCCCgTTC AAggAgCTCTTgACgTTggA TgCTAACAggTgggAAAACC CCTTCCAgCAgATgTggATT AgATTAggCAAggCgAggAT BEC87-GSP1 ... TgATTTTAgCTgCATgTgCACCTgAgAA CgTCATggAAATgTCTTAATTggCTTgCTg gAAgAAAACAAATTgggAggAggAgAA gCgTgTTCCAAAgAACACAATTCAgTgCCTT BEC-32BamHI DX24BamHI ggATCCTgATCTgTggATTgggTTTCgTgg ggATCCgggTg...

Ngày tải lên : 12/08/2014, 03:21

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Molecular signatures of gastric cancer an integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles

... epidemiology and clinical features Gastric cancer etiology 21 The African and Asian enigma 50 Possible molecular pathogenetic attributes of gastric cancer 66 Translocations in epithelial tumors and their ... balanced translocation in IM95 10 Dissecting complex rearrangements: integrating spectral 235 karyotypes and whole genome copy number profiles 10.1 Global in...

Ngày tải lên : 14/09/2015, 08:38

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Some Key Points Of English Grammar

... it.' Prepositions after adjectives characteristic of independent of typical of We hope that the examples will help you find your way around in grammar books so that you can successfully organise ... the basic message of the sentence.) Goethe, who died in 1832, was a famous writer Our car, which is quite old, is still reliable I'd like you to meet our secretaries, some of whom ar...

Ngày tải lên : 05/10/2012, 09:58

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GENOTYPING OF CLOSTRIDIUM PERFRINGENS ISOLATED FROM CATTLE AND PIGS WITH DIARRHEA IN HANOI AND SURROUNDING AREAS, VIETNAM

... number 629 Genotyping of Clostridium perfringens isolated from cattle and pigs with diarrhea in Hanoi and surrounding areas, Vietnam 3.2 Genotyping of C perfringens the toxicity of C perfringens ... Genotyping of Clostridium perfringens isolated from cattle and pigs with diarrhea in Hanoi and surrounding areas, Vietn...

Ngày tải lên : 29/08/2013, 08:14

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Release of anti-cyanobacterial allelochemicals from aquatic and terrestrial plants applicable for artificial floating islands

... surveyed anti-cyanobacterial activities of the plant extracts These findings indicates the possible release of anti-cyanobacterial compounds from vegetation in artificial floating islands, and such ... Hishikaki, Japan) Confirmation of the release of anti-cyanobacterial allelochemicals In order to confirm the release of anti-cyanobacterial allelochemicals,...

Ngày tải lên : 05/09/2013, 09:38

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