DEVELOPING SOFTWARE TOOLS FOR STRUCTURE DETERMINATION OF LARGE PROTEINS BY NMR SPECTROSCOPY

... DEVELOPING SOFTWARE TOOLS FOR STRUCTURE DETERMINATION OF LARGE PROTEINS BY NMR SPECTROSCOPY ZHANG LEI B.SC (HONS.), NUS A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF SCIENCE GRADUATE ... cycle of refinement may go on several times before a high resolution structure can be determined Figure 1.5: Outline of the procedure for protein structure determinat...

Ngày tải lên: 04/10/2015, 15:45

... directly accessed on the screen But the translation is always done by the translator This data base is composed of dictionaries, "formats" and "procedures" of the analysis, transfer and synthesis phases ... phases (the conventional phases of a CAT system) For any given source lexical unit in this data base, VISULEX searches for all the associated information THAM cons...

Ngày tải lên: 17/03/2014, 19:21

... elements at their C termini, including the ‘BG loop’ and the ‘G’-strand (Fig 2) [24] Hortner et al [25] have modelled the structure of the SOCS3 SH2 domain and suggest that the BG loop and bG strand ... SH2 domain (dark grey) and an N-terminal domain of varying lengths (light grey) CIS also contains a small insertion of  60 residues between the SH...

Ngày tải lên: 16/03/2014, 14:20

... domain of each subunit contributes to the formation of the hydrophilic pore ACh binding protein has structural and functional homology to the extracellular ligand binding domain of the nAChR, and ... development of selective drugs is the identification and pharmacological characterization of the various receptor subtypes, and the determination of their prec...

Ngày tải lên: 19/02/2014, 12:20

... showed the accumulation of Ca/Sb precipitates in the vacuoles of the stigma cells as well as in the intracellular spaces between them The stigmatic surface is the main place for signal exchange ... precipitates The spectrum of the material reveals peaks for Ca and Sb The strong decrease of the Ca2+ pool in the pistil at the last stages of pis...

Ngày tải lên: 11/08/2014, 11:21

... determination is the spectral assignment procedure This involves sequence-specific resonance assignment of NMR signals and the assignment of NOESY spectra Resonance assignment forms the basis for characterizing ... obtain the assignments of the Cα and CO of the same residue Then, the CO frequency is used to obtain assignments for the HN and 15N of...

Ngày tải lên: 04/10/2015, 15:52

... Automatic system generation with BitBake / OpenEmbedded Free Software tools for embedded systems © Copyright 2004­2008, Free Electrons Creative Commons Attribution­ShareAlike 2.5 license Jan 24, 2008 http://free­electrons.com Free Software tools for embedded systems ... Best suited for tiny systems, or init ramdisks or initramfs Free Software tools for embedded systems © Copyright 2004­...

Ngày tải lên: 20/10/2013, 00:15

... 50 Software Tools for Speech Research and Development 50. 1 Introduction 50. 2 Historical Highlights 50. 3 The User’s Environment (OS-Based vs Workspace-Based) ... Laboratory, Inc 50. 1 50. 10 File Formats (Data Import/Export) 50. 11 Speech Databases 50. 12 Summary of Characteristics and Uses 50. 13 Sources for Finding Out What is Currently Available 50. 14 Futu...

Ngày tải lên: 27/01/2014, 03:20

... of glutathione and glutathione disulde in human plasma and tobacco leaves by capillary electrophoresis with laser-induced uorescence detection Talanta 65, 986990 Svardal AM, Mansoor MA & Ueland ... curve and the regression equation The average recovery test was made using the standard addition method, and the RSD was generally good when obtained from a series of six plasma s...

Ngày tải lên: 07/03/2014, 05:20

... Cavada et al PPL2, an endochitinase from Parkia platycephala Fig Crystal structure of PPL2 (A) and (B) show two views of the (ab)8 barrel fold of PPL2 The a- helices (red) and b-strands (yellow) are ... The Authors Journal compilation ª 2006 FEBS 3963 PPL2, an endochitinase from Parkia platycephala B S Cavada et al Fig Purification and molecular mass d...

Ngày tải lên: 16/03/2014, 13:20

... presented in this thesis In this thesis, results of our work on the design and development of different instrumentation systems for the rapid determination of Dry Rubber Content in natural rubber ... discussion of the results are included in chapter five of this thesis Finally, in chapter six the summary and general conclusions of the work includi...

Ngày tải lên: 23/03/2014, 21:21

... large excess of contaminating proteins (e.g antibodies in IP experiments) Conclusions The combination of affinity methods for the purification of protein complexes and the identification of their components ... provided by affinity- based methods The common theme of these is the use of an inherent interaction (affinity) of two biomolecules If one of the molecul...

Ngày tải lên: 31/03/2014, 07:20

... cell culture on the fidelity of replication of HCV We tested the impact of long-term in vitro culturing on CIMM-HCV sequences Samples of PCLB-T4a and PCLBT4b, which had been cultured for months and ... that HCV infects these cells as well, and are produced by them However, it is unknown whether the macrophages are modifying or selecting the HCV to make them more in...

Ngày tải lên: 20/06/2014, 02:20