Design and characterization of functional novel oligopeptides

... DESIGN AND CHARACTERIZATION OF FUNCTIONAL NOVEL OLIGOPEPTIDES ONG BOON TEE (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOE THE DEGREE OF MASTER OF SCIENCE DEPARTMENT OF CHEMISTRY NATIONAL ... direction we designed and investigated the self-assembly of a few novel peptides at different conditions Herein we report the design strategy, synthesis and characterization o...

Ngày tải lên: 04/10/2015, 10:25

... box) Recognition of proteins containing CP2- binding motifs and verification of the CP2- binding ability of REST and YY1 that contain the HXPR motif As stated above, none of the 12-mer peptide sequences ... 306–396) of the SPXX region on CP2 is involved in the binding of the ASR motif as well as HXPR (Fig 3) However, we not know whether these two motifs...

Ngày tải lên: 16/03/2014, 18:20

... nucleotide sequence of oyster CaLP cDNA obtained by RACE, a PCR reaction was performed using a pair of specific primers P3 (5¢-GGAAGAATACAGACACGGACAG-3¢) and P4 (5¢-ATAACAACAGTTTATACATCGCTTC-3¢) corresponding ... metabolism and calcium signaling pathways Experimental procedures RNA preparation and cDNA synthesis Adult specimens of P fucata were purchased from Guofa P...

Ngày tải lên: 16/03/2014, 23:20

... (Fig 3A) These results indicated that the b-aryl ether cleavage enzyme accumulated and was stable in the extracellular fraction The extracellular fraction of 2BW-1 generated abundant GG and 4MU ... radiolabeled water was not observed with guaiacol It was clear that the b-aryl ether cleavage enzyme catalyzed the addition of two molecules of H2O (at C...

Ngày tải lên: 17/03/2014, 03:20

... PDZ domain showing 30% identity with the PDZ domains existing in a wide variety of proteins The protein ends by a potential PDZ binding domain motif (SSWY) and contains at least two potential ... presence of activated RhoB (Fig 4D) Regulation of p76RBE mRNA in vitro in thyroid cells As p76RBE was initially isolated from a dog thyroid cDNA library...

Ngày tải lên: 23/03/2014, 21:20

... work was supported in part by an Ontario Graduate Scholarship, Natural Sciences and Engineering Research Council of Canada and the Canada Research Chairs program The authors acknowledge Mr Ka Lun ... the manuscript TC conceived the study, advised on the design and coordination of the experiments, and edited the manuscript All authors read and approved the fin...

Ngày tải lên: 19/06/2014, 08:20

... simulations on the divider can be performed The crystal oscillator is normally a commercially available part and data on its phase noise performance is often available from the manufacturer The ΣΔ ... measured and simulated phase noise for the 3.2-3.3 GHz band The square dots are the simulated data synthesizer phase noise performance The model can serve as a design guide...

Ngày tải lên: 22/06/2014, 22:20

... staining (g) Intense staining of a hyperplastic RA synovial lining cell layer This staining was typical of most areas of RA synovium where the lining was hyperplastic (h) An area of an RA synovial ... stained positively (arrow) (e) Intense staining of individual cells in the lining layer of a typical OA synovium (f) An area of an OA synovium demonstrates a lining lay...

Ngày tải lên: 09/08/2014, 10:20

... and Q (Figures 10 and 11, Tables and 5) The bands near 1339 [31,32] and 758 [33] cm-1 have been found to be indicators of the hydrophobicity of the Trp environment, and a decrease in these band ... indicates the loss of the a-helix during aggregation Meanwhile, the broadening of this band and the increase of the band intensity at 1665 cm-1 implies the increase of the r...

Ngày tải lên: 11/08/2014, 00:23

... specificity and sensitivity (see Additional data file for a detailed analysis and more results) Identifying yeast cell-cycle regulatory motifs To evaluate the performance of WordSpy on biological ... analysis, WordSpy can comprehensively identify real motifs from a large set of regulatory sequences with a high specificity Identifying Arabidopsis cell-cycle regulatory motifs Ce...

Ngày tải lên: 14/08/2014, 16:21

Ngày tải lên: 13/11/2014, 15:51

... DESIGN AND SYNTHESIS OF FUNCTIONAL GRAPHENE COMPOSITES AND THEIR APPLICATIONS JANARDHAN BALAPANURU M.Sc., University of Pune, India A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... bond of graphene and (b) formation of bond between organic functional groups and oxygenated-groups of GO (a) Addition of free radicals to sp2-carbon of grap...

Ngày tải lên: 10/09/2015, 09:13

... overall incidence was found in Iceland and Japan and highest in USA and France The overall prevalence was the lowest in Northern Ireland, UK and Finland, and the highest in Italy, Spain and Martinique ... IDENTIFICATION AND CHARACTERIZATION OF A NOVEL HEART- REACTIVE AUTOANTIBODY IN SYSTEMIC LUPUS ERYTHEMATOSUS: POSSIBLE SEROLOGICAL MARKER FO...

Ngày tải lên: 14/09/2015, 12:42

... demonstrated as a natural antiviral defense in plants Is RNAi also antiviral in animals? Flock house virus (FHV), which can infect both animals and plants, was demonstrated as both an initiator and a ... biogenesis and possible roles of miRNAs and siRNAs 1.3.8 Viral suppressor and miRNA-controlled developmental pathway interaction After discovering miRNAs in...

Ngày tải lên: 16/09/2015, 17:11

... impact on MOST- 1 function 11 9 MOST- 1 Protein 12 1 Aggregation and implication of MOST- 1 function 12 3 Interactors and their possible function with MOST- 1 126 MOST- 1 Expression and Cell Cycle 13 2 Current ... synchronization studies 94 v 4 .11 Yeast two hybrid screening 10 2 4 .12 Overexpression and RNA interference studies 11 0 CHAPTER 5: DISCUSSION Strate...

Ngày tải lên: 16/09/2015, 17:13