ROLE OF THE ERP29 IN MIGRATION, APOPTOSIS AND PROLIFERATION IN BONE MARROW STEM CELLS

... other cells by interacting with actin filaments in migrating cells Integrins can also act as signal transducer in the “inside-out signaling” model The activation of integrins is caused by talin ... capability and the ability of keeping a balanced number of cells during differentiation make BMSCs to be potential therapeutic strategy The novel role of ERp29 in regulating the migration, apoptosis and ... assay) and proliferation (cell proliferation assay) of BMSCs will be evaluated before and after the ERp29 Silencing iii To further study the role of ERp29 in the process of migration, the expression...

The Role of the Media in Promoting and Reducing Tobacco Use doc

... that include several aspects of tobacco advertising and promotion, the use of media by the tobacco industry for corporate Monograph 19 The Role of the Media sponsorship and advertising, the influence ... 2008 xv Preface The work presented in the National Cancer Institute’s Tobacco Control Monograph 19, The Role of the Media in Promoting and Reducing Tobacco Use, is the most current and comprehensive ... Cancer Institute The Role of the Media in Promoting and Reducing Tobacco Use Tobacco Control Monograph No 19 Bethesda, MD: U.S Department of Health and Human Services, National Institutes of Health,...

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Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

... further the role of the IC in the catalysis of ABC transporters, we created, in Abcb1a, six single-site mutants (E552D, N and A, and E1197D, N and A,) and three double-mutants (E552Q ⁄ E1197Q, E552Q ... advantage of the trypsin-sensitive region situated in the linker domain of Abcb1a Following trapping in the absence or presence of Vi and mild-trypsin treatment, the trypsin degradation products of the ... on the nucleotide-binding afﬁnity of the protein [24,39,43] In addition, this conﬁrms the notion that residues E552 and E1197 seem to participate in the catalytic steps after the initial binding...

Tài liệu Rethinking the Role of the State in Finance doc

... Rethinking the Role of the State in Finance Global Financial Development Report 2013 Rethinking the Role of the State in Finance Washington, D.C © 2012 International Bank ... wariness concerning the role of the state in finance that will vary according to confidence in the political system’s ability to promote the public good Determining the proper role of the state ... of key terms used throughout the report The financial system Financial development The state The roles of the state Country The financial system in a country is defined to include financial institutions...

Role of the library in Society ppt

... Benchmarking www.kb.se www.kb.se Training programme for library staff Financed by The Swedish International Development Agency (Sida) In cooperation with The National Library of Sweden, The Ministry of ... Module 1: Role of the library in Society www.kb.se Defining the public library A public library is an organization established, supported and funded by the community, either through local, ... 2000) www.kb.se The Public Library • The public library is the local centre of information, making all kinds of knowledge and information readily available to its users • (Public Library Manifesto,...

the role of the sun in climate change apr 1997

... The ROLE of the SUN in CLIMATE CHANGE THE SUN ON JULY 6, 1979 FROM W J LIVINGSTON The ROLE of the SUN in CLIMATE CHANGE Douglas V Hoyt Kenneth H Schatten ... all the sunspots were in the southern hemisphere Then in April 1705 a spot appeared in the sun' s northern hemisphere These solar changes generated widespread interest In the first decade of the ... cross-section of the sun The viewer is located at the bottom of the page and is looking in the direction of the arrows At the top of the figure, two schematics of sunspots are shown as seen by the viewer...

Báo cáo hóa học: " The role of the surfaces in the photon absorption in Ge nanoclusters embedded in silica" potx

... characterized Ge QDs (2 to 10 nm in size) embedded in silica by thermal annealing of a SiGeO film produced by magnetron sputtering The light absorption spectra of the investigated Page of Ge QDs have ... amount of clustered Ge, the probability of photon absorption is larger the smaller is the QD size By modeling the photon absorption mechanism, we evidenced that it is related to the surfaces of Ge ... that the light absorption in Ge QDs embedded in SiO2 is strongly influenced by the surface of Ge QDs In addition, such an evidence Figure Tauc constant, Ge content, and the surfaces of Ge QDs...

ROLE OF THE ADIPOCYTE IN DEVELOPMENT OF TYPE 2 DIABETES potx

... below), but also indicate that dynein is involved in the initial formation of the droplet (Andersson et al., 20 06) The 32 Role of the Adipocyte in Development of Type Diabetes details of this latter ... insulin-dependent consumption of glucose and thus of major importance in the development of insulin resistance 34 Role of the Adipocyte in Development of Type Diabetes Fig The migration of lipid droplets ... et al., 20 01) 2. 2 VLDL assembly in type diabetes A major factor in the development of the dyslipoproteinemia seen in type diabetes is the increased secretion of VLDL1 (Taskinen, 20 03) This secretion...

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Báo cáo y học: "The role of cyclooxygenase-2 in bone repair" doc

... bone fracture healing J Bone Miner Res 2002, 17:963-976 Einhorn TA Do inhibitors of cyclooxygenase-2 impair bone healing? J Bone Miner Res 2002, 17:977-978 Zhang X, Schwarz EM, Young DA, Puzas ... activity of a glucocorticoid-regulated inflammatory cyclooxygenase Proc Natl Acad Sci USA 1992, 89:4888-4892 Raskin JB: Gastrointestinal effects of nonsteroidal anti-inflammatory therapy Am J ... selectivity of this group of compounds might allow inflammation to be inhibited with minimal effects on certain homeostatic mechanisms, their role in bone metabolism and repair remains unclear Review of...

THE ROLE OF THE COURT IN PROTECTING HUMAN RIGHTS IN PRESENT VIETNAM

... role of the court in protecting human rights On the basis of the internal content of the term role , content and characteristics of protecting the human rights by the court, the role of court in ... enhance the role of the Court in protecting human rights in Vietnam 4.3.1 Raising awareness of the Party, State and people of the role of the Court in protecting human rights Awareness of the Party, ... awareness of the Party, the state and the people about the role of court in protecting human rights - The awareness of the Party and the state about the role of court in protecting human rights - The...

Báo cáo hóa học: "Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion" doc

... Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion Journal of Translational Medicine ... Y: Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation: report of a case ... difficult to determine, imaging of transplanted stem cells is crucial in order to investigate the attitude of the engrafted stem cells to the hosting myocardium [26] The number of treated patients...

Báo cáo y học: "The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells" pot

... analyze the impact of different chromatin modifiers on the replication timing profile of mouse ES cells We show that, while early replication in ES cells correlates with peaks of increased histone ... staining and cell cycle profiles of the mutant ES cell lines analysed Supplementary Figure contains replication timing profiles of all loci analysed in each of the mutant ES cell lines analysed ... Collectively, these data suggest that only a minority of loci (5/23; supplementary Figure in Additional data file 2) change their replication timing in response to severe reduction of DNA methylation...

Effects of combined mechanical and pulsed electromagnetic field stimulations on the osteogenesis of bone marrow stem cells

... (cancellous) bone Cortical bone forms the dense outer shell of most bones and it accounts for 80% of the total bone mass Cortical bone is mostly found in the shaft portion of long bones and the outer ... EFFECTS OF COMBINED MECHANICAL AND PULSED ELECTROMAGNETIC FIELD STIMULATIONS ON THE OSTEOGENESIS OF BONE MARROW STEM CELLS NG KIAN SIANG (B Eng (Hons), NUS) A THESIS SUBMIITED FOR THE DEGREE ... cancellous bone On the other hand, cancellous bone consists of a network of struts surrounding interconnected spaces It is the spongy interior bone tissue which makes up 20% of the total bone mass...

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Báo cáo sinh học: "Compound developmental eye disorders following inactivation of TGF signaling in neural-crest stem cells" doc

... targeting to inactivate TGF signaling in NC stem cells and, as a result, in ocular NC derivatives in order to assess the actions of TGF on these cells during eye development Results Neural-crest ... (d) Tgfbr2 (e) NCSC-specific recombination Tgfbr2 mutant pSmad2 (f) Tgfbr2 (g) pSmad2 Figure Inactivation of TGF signaling in ocular NC-derived cells (a,b) TGF ligand and receptor expression in ... At E18, expression of Brn3A, Pax6 and neurofilaments defines distinct layers of the developing retina in control eyes (Figure 5h) In Tgfbr2-mutant mice, however, patterning into cell layers was...

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