Role of the nucleus incertus in cognition

... Establishing the stress models 2.2 Investigation of the role of the NI in stressor-induced HP-mPFC LTP modulation Role of the NI in stress-induced modulation of mPFC-mediated working memory The current ... research implicates the potential role of an emerging structure, the nucleus incertus (NI) in stress and memory modulation (Ryan et al., 2011) Nucle...

Ngày tải lên: 30/09/2015, 10:11

Ngày tải lên: 25/10/2013, 05:20

... number of differences in the N-terminal domain (located on the matrix side) It is likely that the N-terminal domain is involved in protein protein interactions with other hydrophilic domains of neighboring ... chain was established with succinate and glycerol3-phosphate as substrates Complex II activity was determined after addition of succinate, followed by inhibition b...

Ngày tải lên: 19/02/2014, 16:20

... strengthening the struggle against the expansion of mega projects of pulp and paper companies in the sul-rio-grandense Pampa - 28 - Women raise their voices against tree plantations Final reflections ... because, in general, they are working in fishing activities There is much resistance of local residents - 26 - Women raise their voice...

Ngày tải lên: 08/03/2014, 10:20

... one amino acid in the C-terminus of the laccase, giving the Tr(L559G) and Sc(L559A) mutants, reduced the turnover of the mutant proteins For the substrate ABTS, the Michaelis constant of the Sc(L559A) ... Function of C-terminus in M albomyces laccase Our results clearly show the critical role of the last amino acids in the C-terminus of...

Ngày tải lên: 16/03/2014, 00:20

... for N2C2 and N2Cc In conclusion, the accessibility of the active site was better in the protein bearing the N2 domain than in the protein bearing the Nc domain Thus, the accessibility of the active ... both the N-terminal and C-terminal domains of hoPLRP2 contributed to the stability of the protein in the presence of the water–lipid interfac...

Ngày tải lên: 16/03/2014, 06:20

... homoserine kinase mevalonate kinase phosphomevalonate kinase (GHMP) kinase superfamily of enzymes that are known to have a left-handed b–a–b fold, which is found in other RNA ⁄ DNA binding proteins ... both ATP and mevalonate inhibit the binding of MVK to LHR mRNA, the present investigation examines whether the catalytic site of this multifunctional protein partic...

Ngày tải lên: 16/03/2014, 06:20

... we examined the readers’ rating of the polarity of reviews in their entirety, while in the second experiment we examined the readers’ rating of the same reviews based on reading single sentences ... single sentences extracted from the same 16 reviews: the last sentence and the second sentence of each review The last and the second sentence of each...

Ngày tải lên: 23/03/2014, 16:20

... contribution of the autophosphorylation process to heme sensing and catalysis The results obtained should aid the clarification of the general role of autophosphorylation in catalysis by eIF2a kinases ... Pichierri F, Martinkova M & Shimizu T (2008) Elucidation of the heme-binding site of heme-regulated eIF2a kinase (HRI) and the role of the regu...

Ngày tải lên: 28/03/2014, 23:20

... performance of large dam projects, including those funded by the World Bank Role of the United States In Achieving Reform The United States should take a lead in pushing the World Bank to incorporate ... Removing this ban would potentially open the floodgates for World Bank financing of large-scale unsustainable logging operations in some of...

Ngày tải lên: 29/03/2014, 08:20

... cleavage of the linker [22] Although these results provided valuable suggestions for the role of the P-gp linker region, the molecular details, such as the involvement of the linker region in substrate ... in purple in Fig 7) in the MsbA dimer In the inward-facing state, there appears to be less interaction between the linker region and each su...

Ngày tải lên: 29/03/2014, 23:20

... Lgt4 Results In order to investigate the function of the glycosyltransferase enzymes involved in the biosynthesis of LOS of M catarrhalis, and to gain some insights into the mechanism of serotype ... irradiating each of the anomeric signals in turn to obtain the H chemicals shifts of the corresponding remaining ring protons Again, assignment of the Kdo...

Ngày tải lên: 30/03/2014, 08:20

... reduction of fracture fragments including alignment of the intermediate fragment to the trochlear face In the operative report precise description of the fracture pattern including presence of an intermediate ... Reduction of the intermediate fragment was performed using a clamp between the distal and proximal fragment of the fracture into the inter...

Ngày tải lên: 20/06/2014, 04:20

... reduction of fracture fragments including alignment of the intermediate fragment to the trochlear face In the operative report precise description of the fracture pattern including presence of an intermediate ... Reduction of the intermediate fragment was performed using a clamp between the distal and proximal fragment of the fracture into the inter...

Ngày tải lên: 20/06/2014, 07:20

... effects of the del11 allele on many traits of economic importance in the South Devon and quantifies the multivariate impact of the del11 alleles on the traits recorded in a random sample of the breed ... breed are assessed in light of the results of the analyses Role of myostatin in South Devon cattle 223 MATERIALS AND METHODS 2.1 Animals a...

Ngày tải lên: 09/08/2014, 18:21