Electrophysiological study to explore the functional consequences of ng expression on neuroblastoma cells (n2a)
... according to their concentration gradient, thereby causing changes in their cytosolic concentration These changes trigger other cellular reactions that result in the message being transmitted along ... resolution of the selectivity and regulation of individual ion channels The outside-out version permits study of changes occurring in response to stimulations of ion channel...
Ngày tải lên: 30/09/2015, 06:42
... this study was to explore the efficacy of orthotic treatment for mechanically induced 1st MTP joint pain and to investigate whether any change in pain correlated with changes in foot and ankle kinematic ... produced foot orthoses for other indications [45,46] Contrary to the hypothesised mode of action [16], the exploratory analysis revealed that the reduct...
Ngày tải lên: 10/08/2014, 21:24
... observed was attributable to the HRSV F protein Host range of HRSV-mediated fusion To determine the host range of HRSV F mediated fusion using the quantitative fusion assay 293T effector cells ... interpretation The assay described herein is a means of quantifying the fusion activity of the HRSV F protein This assay has multiple applicatio...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc
... indication of anti-tumour activity [13,15,16] In a phase I study by McGinn et al to find the MTD of gemcitabine in association with RT to 50.4 Gy in 1.8 Gy daily fractions in patients with locally ... further study considering the (potential) occurrence of both acute and late toxicity As in our study, the acute toxicity consisted of dose- limiti...
Ngày tải lên: 09/08/2014, 09:22
báo cáo hóa học:" Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells" potx
... psoriasis [15,17] To investigate the immunomodulatory effects of Panax ginseng, genechip analysis was used to examine the gene expression profile of TNF-α-treated human monocytic U937 cells with or ... results may contribute to the understanding of the molecular mechanisms of the immunomodulatory effect of ginseng and ginsenosides on TNF-α-mediated...
Ngày tải lên: 18/06/2014, 15:20
Exploration of the functional significance of mig 2 in human cancer cell susceptibility to cytotoxic agents and cell growth control a pilot study
... all their signaling effects by recruiting and activating different intracellular signaling and adaptor proteins ECM binding initiates clustering of integrins in the plane of the membrane and ... Briefly, a pilot study was initiated to explore the functional significance of an uncharacterized gene mig- 2 in human cancer cells, focusing on cell suscep...
Ngày tải lên: 05/10/2015, 22:15
A study to indicate the importance of consumer based-brand equity on consumer perception of brand (a case study of fast food restaurants).pdf
... increase the competitive advantage of the fast food restaurant The basic attribute of a fast food restaurant are also important for a fast food restaurant to excel because the strength of a brand ... qualities, brand loyalty, brand awareness, brand association and other propriety assets According to him, Brand loyalty has to with the level of...
Ngày tải lên: 24/09/2012, 17:19
Analytical study to minimize the engine exhaust emissions and safe knock limit of CNG powered four-stroke SI engine
... related to the compression ratio, and engine knock occurs more easily if the compression ratio is increased In order to fully understand the knock phenomenon and to find possible way to avoid knock ... fuel and engine design The present work involves a theoretical approach to develop a computational model of combustion in SI engine in order to underst...
Ngày tải lên: 05/09/2013, 15:28
A computational study to investigate the effects of insulation and EGR in a diesel engine
... of insulation of an IDI diesel engine The indicated power increased at the adiabatic case 30% and 22.5% in part and full loads respectively Although in the EGR applying case, performance characteristics ... also worked as a Professor and Head of department in the Department of Mechanical Engineering, Vidya Vikas Institute of Technology, Andhra Pradesh,...
Ngày tải lên: 05/09/2013, 16:11
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... raise the possibility that GSK3 may help to coordinate increases in glucose uptake and glycogen synthesis allowing for more effective ÔchannellingÕ of glucose into glycogen in response to insulin ... Effects of insulin, Li and SB-415286 on signalling elements implicated in the regulation of GSK3 and GS To further understand the effects of Li and...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase pdf
... with the amino group and the N3 atom of the cytosine (Fig 1) This study uses site-directed mutagenesis to further explore the contribution of these amino acids interacting with the pyrimidine ring ... consisting of three domains, the CORE, the LID and the NMPbind [1] A characteristic of bacterial CMP kinases is an extension of the NMPbind domain by 40...
Ngày tải lên: 16/03/2014, 10:20
báo cáo hóa học: " An exploratory study to evaluate the utility of an adapted Mother Generated Index (MGI) in assessment of postpartum quality of life in India" potx
... subject was reviewed and it was decided to adapt the index to the Indian setting, possibly at the expense of limiting its comparability to other settings In an attempt to keep the index as simple ... number of areas identified to six, to keep the scoring points at 10, to allow 12 spending points and to allow the mother and child counselors to admini...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Preferences of diabetes patients and physicians: A feasibility study to identify the key indicators for appraisal of health care values" doc
... is based on the levels of assessment and appraisal as shown in Table The appraisal of health care services presumes that preferences can be measured and can be made available to the policy and ... respectively The general practitioners had an average of 171 diabetes patients in their practices and the diabetes specialists had an average of 331 diab...
Ngày tải lên: 20/06/2014, 15:20
báo cáo khoa học: "A Study to investigate the role of p27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma" pptx
... post-transcriptional level [20] The aim of this study was to investigate the role of p27 and cyclin E immunoexpression as a prognostic factor in early breast carcinoma Methods A database of all wide local excisions ... there were racial differences in breast carcinoma When disease stage and age at diagnosis were adjusted for, it was shown that...
Ngày tải lên: 09/08/2014, 01:24