Integrating biological insights with topological characteristics for improved complex prediction from protein interaction networks

... catalogued, distinct groups of proteins forming complexes can be isolated from them: proteins within a complex form many interactions with each other than with proteins not in the complex Quite naturally, ... protein interactions from an organism are typically assembled in the form of a network with the proteins as nodes and the interactions among them as edges, commonly calle...

Ngày tải lên: 16/09/2015, 12:17

... neighbors In the beginning, local coordinates are computed only for the cluster of nodes within the same radio range Later, those local coordinates are consolidated into an overall base for the ... not include the shrinking areas but only the dark-shaded growing areas All the other weights π k=3 actually include the shrinking areas in their product Note that all weights π k=3 except...

Ngày tải lên: 22/06/2014, 19:20

... repeated measures made at each practice Separate models were developed to assess the association between the combined practice capacity for change score and change in the practice rate of PSD from ... score, a supplemental analysis demonstrated a strong association with instrumental change capacity (3.2%, p = 0.002); a weaker association with motivation to ch...

Ngày tải lên: 11/08/2014, 05:21

... repeated measures made at each practice Separate models were developed to assess the association between the combined practice capacity for change score and change in the practice rate of PSD from ... score, a supplemental analysis demonstrated a strong association with instrumental change capacity (3.2%, p = 0.002); a weaker association with motivation to ch...

Ngày tải lên: 11/08/2014, 16:21

... likely noise Addressing this limitation is an important area for continued effort Data availability Data are available upon request Abbreviations BFS, breadth-first search; CC, co-conservation; ... million years ago (MYA) from O157, an estimated 100 MYA from Salmonella, 200 MYA from Pseudomonas, and 1,200 MYA from Bacillus Thus, we examined a combination of pathogenic and non-pathogenic o...

Ngày tải lên: 14/08/2014, 08:20

... hypothetical protein- protein interaction network Each sphere represents a protein and the connecting lines represent protein- protein interactions Within an interaction network, smaller local interaction ... and independently fusing these domains with candidate interacting proteins [21,22] Constructs encoding these fusion proteins are transformed into yeast cells; if the two...

Ngày tải lên: 14/08/2014, 14:21

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 01/10/2015, 17:27

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 03/10/2015, 21:56

... thesis A survey on computational methods for identifying conserved protein complexes between species: in this survey, computational methods for identifying conserved protein complexes are grouped ... present a definition for the problem of identifying conserved protein complexes between species from protein interaction data We then review t...

Ngày tải lên: 04/10/2015, 07:57

... developed for the automatic acquisition of novel lexical entries for machine translation 16 We are in the process of building an English dictionary, and intend to use the same approach for building ... [-a] predicate into a [+a] predicate, i.e., a non-atomic event becomes atomic if it is associated with a singular NP object The parameterized mappings that we have constructed...

Ngày tải lên: 17/03/2014, 08:20

... (iii) an evaluation of the resampling accuracy for the projective particle filter; (iv) a comparison of the performance of the projective particle filter and the standard particle filter using three ... (1) the improvement in sample distribution with the implementation of the projective transform, (2) the improvement in the position error of the vehicle by...

Ngày tải lên: 21/06/2014, 08:20

... by trypsin treatment (0.05% trypsin, 0.02% EDTA; Biochrom) at 75% confluence Flow cytometry analysis of cells Either isolated cells from OC were directly used for flow cytometric analysis or cells ... functionality of cell surface molecules on human mesenchymal stem cells J Biomed Sci 2003, 10:228-241 Reyes M, Verfaillie CM: Characterization of multipotent adult pro...

Ngày tải lên: 09/08/2014, 01:23

... article as: Leykum et al.: The importance of organizational characteristics for improving outcomes in patients with chronic disease: a systematic review of congestive heart failure Implementation ... effectiveness of combinations of characteristics Because one way that individuals can navigate uncertainty is through relationships, interconnections may...

Ngày tải lên: 10/08/2014, 10:23

... CNF Control for Continuous-Time Systems with Input Saturation In this chapter, I will present a design procedure of composite nonlinear feedback control for general multivariable systems with actuator ... procedure of composite nonlinear feedback (CNF) control for general multivariable systems with actuator saturation I will consider both the state...

Ngày tải lên: 15/09/2015, 22:15

... conclusion, MALDI-TOF MS combined with magnetic beads is one useful tool for integrating separation and analysis of complex mixtures of proteins With the panel of four selected biomarkers, we achieved ... a by serum protein profiling of patients with chronic liver diseases Hepatology 2005; 41:40-47 28 Cho WC, Yip TT, Ngan RK, Yip TT, Podust VN ProteinChip array...

Ngày tải lên: 25/10/2012, 11:18