Local immunopotentiation of the bladder in response to BCG i

Local immunopotentiation of the bladder in response to BCG immunotherapy

... clinical trial using a novel combination of interferon alpha and BCG, to explore the mechanisms of action of BCG immunotherapy We have developed a reliable protocol for measuring cytokines in the ... group of cell cycle inhibitory molecules (see Fig 1.1) p16 together with p15 inhibit phosphorylation of the retinoblastoma protein (Rb), thereby inhibiting the cell cyc...

Ngày tải lên : 16/09/2015, 08:31

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báo cáo khoa học: " Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection" ppsx

... compartmentalized expression of the isoflavonoid pathway leading to the synthesis of isoflavones in the roots and cotyledons and an inducible isoflavonoid-phytoalexins synthesis in the leaves of pathogen stressed ... anthocyanin pathway ESTs in tomato [8] CHS is the key enzyme diverting the substrate, naringenin chalcone to the flavonoid and isoflavonoid bran...

Ngày tải lên : 12/08/2014, 05:20

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Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt

... ratio of the bronchodilatory response in COPD The impact of this issue on the interpretation of study results is best illustrated by considering the variability of a single dose level within and ... of the comparators included in this analysis The most striking feature of the plot is that the response to indacaterol at the plateau exceeds the r...

Ngày tải lên : 12/08/2014, 13:22

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Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx

... Figure Cytokine response to chronic aspiration of gastric fluid Cytokine response to chronic aspiration of gastric fluid Cytokine levels were evaluated in the bronchoalveolar lavage (BAL) fluid ... model of chronic aspiration described herein, chronic aspiration can initiate an inflammatory response consisting of macrophages and T cells and characterized...

Ngày tải lên : 12/08/2014, 15:21

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The roles of shca proteins in response to oxidative stress 1

... separated to the nuclear and cytoplasmic fractions The levels of FOXO3a, TopBP1 (nucleus control), and p6 6shcA (cytoplasm control) were determined by western blot Note that four fold more total proteins ... using anti-phospho-tyrosine antibodies (C) Point mutation analysis to identify the tyrosine residues that was phosphorylated in the presence of H O p5 2shcA carrying...

Ngày tải lên : 14/09/2015, 14:17

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The roles of shca proteins in response to oxidative stress 2

... for in vitro kinase assay as described in Fig 4.5A -1 02- A p-Erk1 /2 Erk1 /2 H2O2(mM) 0.1 0 .2 0.4 0.5 pMSCVp52ShcWT 0.1 0 .2 0.4 0.5 pMSCVp52ShcS29A B p 52 p46 pMSCVp52S29A pMSCVp52WT ShcA- /- ShcA ... concentrations of H2O2 ERK activation was analyzed with Western blot (B) Expression of p5 2ShcA or p5 2ShcA S29A in retroviral infected MEFs -104- A P-Erk1 /2 Erk1 /2 H2...

Ngày tải lên : 14/09/2015, 14:18

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Báo cáo khoa học: BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells pdf

... support the hypothesis that BRCA1 enhances TRAIL s ability to mediate apoptosis in breast cancer cell lines Discussion There is increasing interest in the association between hypoxia and BRCA1 ... induce apoptosis in breast cancer cells Therefore, we assessed the requirement for functional BRCA1 in TRAIL- stimulated apoptosis HCC1937 cells have...

Ngày tải lên : 30/03/2014, 03:20

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Báo cáo lâm nghiệp: "Chemical composition of the periderm in relation to in situ water absorption rates of oak, beech and spruce fine roots" doc

... beech and spruce trees measured in situ and relate them to the contents of suberin and lignin in the root periderm This approach contrasts with earlier laboratory studies on the relationship of ... tip in all species At 500 mm distance from the tip, periderm thickness had increased to 50 µm in beech and spruce, and to 70 µm in oak In beech...

Ngày tải lên : 08/08/2014, 01:21

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Báo cáo y học: "volution of an adenocarcinoma in response to selection by targeted kinase inhibitors" potx

... (predominantly over-expressed in skin relative to lung) These included many molecular mechanisms of cancer and cancerrelated signaling pathways, such as mammalian target of rapamycin (mTOR) signaling, ... Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors Genome Biology 2010 11:R82 Submit your next manuscript to BioMed Central a...

Ngày tải lên : 09/08/2014, 20:22

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báo cáo khoa học: "Evaluation of the microbial growth response to inorganic nanoparticles" ppt

... contribute to the agglomeration of the nanoparticles The surface charge on the nanoparticles in solution allows the nanoparticles to attract to one another because of the influence of ions from the ... minutes to record the growth of the microbes from inoculation through late exponential phase using a spectrophotometer set at 600 nm The growth rate of...

Ngày tải lên : 11/08/2014, 00:22

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báo cáo khoa học: "Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana" pdf

... article as: Schuler et al.: Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana BMC Plant Biology ... incorporated into the GSEA tool of GeneTrail as individually defined categories Contrary to the GeneTrail- predefined categories the genes of MapM...

Ngày tải lên : 11/08/2014, 11:20

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Báo cáo y học: " Glucocorticosteroid-sensitive inflammatory eosinophilic pseudotumor of the bladder in an adolescent: a case report" pdf

... form of allergic cystitis, that is, eosinophilic cystitis [1] Manifestations of eosinophilic cystitis are not specific and can mimic those of other inflammatory and malignant bladder disorders, and ... this case of an inflammatory pseudotumor of the bladder is one of only a few cases reported in the literature that have been treated with complete conserva...

Ngày tải lên : 11/08/2014, 17:21

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báo cáo khoa học: " Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought tolerance" pps

... Cite this article as: Jain and Chattopadhyay: Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought tolerance BMC Plant Biology ... internal recycling of CO(2) by pods of chickpea (Cicer arietinum L.) subjected to water deficits J Exp Bot 2001, 52(354):123-131 22 Ahmad F,...

Ngày tải lên : 12/08/2014, 03:21

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Báo cáo khoa học: "RAGE: Exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes" pps

... failure to clear the organism [6,7] In the initial phase of infection, Listeria binds to splenic macrophages and is internalized; Listeria produces products that activate nuclear factor-kappa B and ... Pamer [5], in the first few days of Listeria infection, the innate response is critical for early bacterial clearance and host survival The adaptive response...

Ngày tải lên : 13/08/2014, 10:20

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REGULATION OF CHOP TRANSLATION IN RESPONSE TO eIF2 PHOSPHORYLATION AND ITS ROLE IN CELL FATE

... N-terminal domain of HRI and in an insert region in the protein kinase domain of HRI (63) Heme, in the presence of iron, binds to α and β globin chains in ratio of 1:2:2, respectively In response to iron ... Palam REGULATION OF CHOP TRANSLATION IN RESPONE TO eIF2 PHOSPHORYLATION AND ITS ROLE IN CELL FATE In response to different en...

Ngày tải lên : 24/08/2014, 12:32

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