Computational study of therapeutic targets and ADME associated proteins and application in drug design
Computational study of therapeutic targets and ADME associated proteins and application in drug design
... process of drug discovery - VI - Computational study of therapeutic targets and ADME- associated proteins and application in drug design List of Tables LIST OF TABLES Table 1-1: A brief history of ... pharmacogenetic prediction of drug responses 159 - VII - Computational study of therapeutic targets and ADME- associated proteins and...
Ngày tải lên: 15/09/2015, 22:19
Computational study of shape, orientation and dimensional effects on the performance of nanowire fets
... COMPUTATIONAL STUDY OF SHAPE, ORIENTATION AND DIMENSIONAL EFFECTS ON THE PERFORMANCE OF NANOWIRE FETS KOONG CHEE SHIN (M.ENG, NUS) A THESIS SUBMITTED FOR THE DEGREE OF MASTER ENGINEERING ... will concentrate on the effects of nanowire cross-sectional shapes, orientations and sizes on the performance of NW based on their electronic bandstru...
Ngày tải lên: 03/10/2015, 21:56
A cross cultural study of giving compliments and responses in english and vietnamese
... “Communication is, rather, the successful interpretation by an addressee of a speaker’s intent in performing a linguistics act” (Georgia M Green, Natural Language Understanding, p.1) And a linguistics ... data that reveal the cultural orientation of language learners (In many languages, compliment responses require the language user to walk a delicate line between appearin...
Ngày tải lên: 14/12/2013, 00:41
a study of injection locking and pulling in oscillator
... energy at quency In fact, if (33) (34) 3A linear oscillator can be defined as one in which the loop gain is exactly unity for all signal levels RAZAVI: STUDY OF INJECTION LOCKING AND PULLING IN OSCILLATORS ... between ! and the lower end of the lock range) ! (the 0! 0! RAZAVI: STUDY OF INJECTION LOCKING AND PULLING IN OSCILLATORS Fig 1419 Phase variation...
Ngày tải lên: 08/07/2014, 17:03
Báo cáo khoa học: "Immunohistochemical study of caveolin-1 and -2 in the rat retina" pps
... ,D( reyal mrofixelp retuo ni deniatsonummi ylesuffid saw 2-niloevaC )worra ,C( noitacol dna ygolohprom ni sllec relluM lacitnedi ,sllec lailg fo ssecorp eht ni dnuof saw gniniatsonummi-2-niloevaC ... dna ,02 -neewT %1.0 gniniatnoc SBT ni semit eerht dehsaw erew stolb ehT 2-niloevac ro ,1-niloevac rehtie tsniaga ydobitna esuom htiw h rof detabucni neht erew senarbmeM h rof )lCaN Mm 051 dna ,4....
Ngày tải lên: 07/08/2014, 18:21
Báo cáo y học: "A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity" doc
... preparation, statistical analyses and drafted the manuscript A- KL participated in the design of the study and the statistical analyses HK and LA performed the logistic regression analysis LP and LK were ... 71% and 72%, respectively, are female; the mean age was 51 ± 13 years in cases and 54 ± 12 in controls Information about RF and anti-CCP antibody status was availab...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo lâm nghiệp: "Reconstruction of crown length of Norway spruce (Picea abies (L.) Karst.) and Silver fir (Abies alba Mill.) – technique, establishment of sample methods and application in forest growth analysis Peter SPATHELF" ppt
... Development of crown ratio (cr) of thinned and unthinned Norway spruce and Silver fir up to 10 years since thinning With the exception of thinned Silver fir all trees are declining in crown ratio, ... Note: Silver fir whorls are in the upper part (stands 1–3 and 5), Norway spruce whorls in the lower part (stands and 6–9 ) of the table *l: Loca...
Ngày tải lên: 08/08/2014, 01:21
Biointormatics of targeted therapeutics and applications in drug discovery
... Bioinformatics of Targeted Therapeutics and Applications in Drug Discovery x Bioinformatics of Targeted Therapeutics and Applications in Drug Discovery List of Tables Chapter Table Statistics of ... multi-target drugs and drug combinations, which are more efficacious and vii Bioinformatics of Targeted Therapeutics and Applications in Drug...
Ngày tải lên: 12/09/2015, 09:10
pharmacokinetics and metabolism in drug design
... Methods and Principles in Medicinal Chemistry focuses on the impact of pharmacokinetics and metabolism in Drug Design Pharmacokinetics is the study of the kinetics of absorption, distribution, metabolism, ... Typesetting TypoDesign Hecker GmbH, Leimen Printing Strauss Offsetdruck, Mörlenbach Binding Osswald & Co., Neustadt (Weinstraße) ISBN 3-527-30197-6 Pharmacokinetics...
Ngày tải lên: 11/04/2014, 10:03
Báo cáo y học: "Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia" ppt
... confirm the diagnosis of VAP What is clear is that avoiding delay in sampling and initiating therapy quickly are more important than the type of quantitative technique used Treatment strategy and ... Rello The investigational new drug tigecycline, the first of a new synthetic class of antibiotics called the glycylcyclines, has an extended broad spectrum of activity t...
Ngày tải lên: 12/08/2014, 20:20
A COMPUTATIONAL STUDY OF FREE RADICALS IN CHEMISTRY AND BIOLOGY
... cyclase and activates smooth muscle relaxation [5, 6] Ignarro made two key observations – that NO• has an effect of relaxing an artery [7] and this same gas inhibits platelet aggregation and activates ... Abstract Free radicals are involved in many aspects of our daily lives, but due to their transient nature and high reactivity, many free radicals and free radical p...
Ngày tải lên: 11/09/2015, 21:28
Computational study of adsorption and diffusion in metal organic frameworks
... linkers in various MOFs (IRMOF-1, IRMOF-3, IRMOF-1-4NH2, IRMOF-6, IRMOF-8, IRMOF-12, IRMOF-14, IRMOF-18 and IRMOF-993) and found that the larger linkers bind more H2 molecules and addition of ... predicted in catenated and non-catenated MOFs To study the adsorption and diffusion of a model drug (ibuprofen) in mesoporous MIL-101 and UMCM-1 The energetics and dyn...
Ngày tải lên: 14/09/2015, 08:49
Study of the associated proteins of STAT3 and characterization of their functions roles of GRIM 19 and PIN1 in the regulation of STAT3 activity
... STUDY OF THE ASSOCIATED PROTEINS OF STAT3 AND CHARACTERIZATION OF THEIR FUNCTIONS: ROLES OF GRIM- 19 AND PIN1 IN THE REGULATION OF STAT3 ACTIVITY LUFEI CHENGCHEN B Sc (Hons), NUS A THESIS ... fold of human Pin1 37 Figure 3.1 Interaction of Stat3 and GRIM- 19 71 Figure 3.2 Association of endogenous Stat3 and GRIM- 19 75 Figure...
Ngày tải lên: 15/09/2015, 17:10