Role of substance p in sepsis

... workflow of multiplex immunoassay Plasma pro-inflammatory cytokine profile in wild-type and PPTA-/- septic mice Plasma anti-inflammatory cytokine profile in wild-type and PPTA-/- septic mice ... pro-inflammatory mediators in polymicrobial sepsis The combined data provided further support for the role of SP in polymicrobial sepsis In addition to the use of neurokinin rece...

Ngày tải lên: 14/09/2015, 14:06

... Neurokinin-1 receptor PMN Polymorphonuclear PPT-A Preprotachykinin-A PGE2 Prostaglandin E2 RT-PCR Reverse transcription-polymerase chain reaction SP Substance P TNF-α Tumor necrosis factor- α TRPV1 ... understanding the role of mediators that contribute to the pathophysiology of burn- induced ALI However, the role of SP in inducing inflammation in the lungs after...

Ngày tải lên: 14/09/2015, 08:26

... signaling is independent of Toll-interleukin receptor domain-containing adaptor protein Drug Metab Dispos 36, 95–101 10 Ghose R, Guo T & Haque N (2009) Regulation of gene expression of hepatic drug ... abnormalities in microsomal drug- metabolizing function during the late phase of sepsis [6] However, the underlying mechanisms involved in hepatic dysfunction during sepsis...

Ngày tải lên: 14/02/2014, 18:20

... control at t ¼ for each peptide The percentage of degradation was calculated by comparing the area of the peaks of the intact peptide at t ¼ and t ¼ 60 Binding assays Binding assays were carried ... [33], the peptides containing a b-amino acid substitution in position have increased stability compared to the corresponding a- amino -acid- containing peptides...

Ngày tải lên: 08/03/2014, 08:20

... 0.71 Principal-component analysis for cytokines and neuropeptides in synovial fluid from 23 patients with long-standing RA, and for the ESR BN/GRP, bombesin /gastrin-releasing peptide; CGRP, calcitonin-gene-related ... concentrations of three cytokines (TNFα, IL-6, and MCP-1) and several neuropeptides (BN/GRP, SP, NPY, VIP, and CGRP) in the synovial fluid from...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 13:22

... of PC-12 cells strongly induces MMP-10 gene expression We have previously identified the expression of the neurotrophin NGF and the pain-associated neuropeptide substance P in the human IVD and ... to increased nociception in painful IVD degeneration Page of (page number not for citation purposes) The aim of the current study was to examine the gene...

Ngày tải lên: 09/08/2014, 14:22

... asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro Journal of Inflammation 2011 8:18 Page of Submit your next manuscript to BioMed ... that in turn induce increased calcium concentration in ASMC, airway smooth muscle contraction, and airway hyper-responsiveness For example, IL-8 has b...

Ngày tải lên: 11/08/2014, 03:20

... asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro Journal of Inflammation 2011 8:18 Page of Submit your next manuscript to BioMed ... that in turn induce increased calcium concentration in ASMC, airway smooth muscle contraction, and airway hyper-responsiveness For example, IL-8 has b...

Ngày tải lên: 11/08/2014, 06:23

... has been identified as a key proinflammatory mediator in experimental acute pancreatitis (AP) SP is a product of the preprotachykinin -A (PPTA) gene, and it binds mainly to neurokinin- 1 receptor ... either an aromatic or an aliphatic amino acid (Severini et al., 2002) Tachykinins are produced by three genes in mammals, namely preprotachykinin A (PPTA), preprotachykini...

Ngày tải lên: 09/09/2015, 17:54

... ethanol- regulated genes were involved using KEGG (Kyoto Encyclopedia of Genes and Genomes) [36] and GenMAPP (Gene Microarray Pathway Profiler) [37] analysis As shown in Table 2, only ITGB4 was found to be involved ... considering the reported high expression of the ankyrin-repeat oncoprotein (gankyrin) in human hepatocellular carcinoma Gankyrin binds to the cell-...

Ngày tải lên: 31/10/2012, 15:28

... in raising the profile of women in management or leadership roles Early leadership theories In the 18th and 19th centuries, philosophers suggested a theory of leadership which was termed the ... although the leadership literature has played a significant role in raising the profile of women in management, further advances are required in...

Ngày tải lên: 08/10/2013, 15:56

... globalization II Review of Institution Building in the Financial Sector A Main driving forces of institution building A review of the developments of China s financial sector over the past 20 years reveals ... unique role in institution building in the financial sector They help to mitigate financial repression in China, to establish sound...

Ngày tải lên: 18/10/2013, 07:15

... Atlanta, GA 30333 SUGGESTED CITATION Centers for Disease Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by ... Committee and the Advisory Committee for Elimination of Tuberculosis published a joint statement on the use of BCG va...

Ngày tải lên: 15/02/2014, 13:20