Role of central nervous system ceramides and free radicals in a mouse model of orofacial pain
Role of central nervous system ceramides and free radicals in a mouse model of orofacial pain
... complicated because of the region’s density of anatomical structures, rich innervations and high vascularity Orofacial pain is defined by the American Academy of Orofacial Pain (AAOP) as pain conditions ... as brushing and touch, are painful (allodynia), and normally mild pain stimuli like pinprick are much more painful than usual (hyperalgesia) Hyperalgesia in the area of injury is also known as ... sensibility including touch and thermal sensation without pain, as well as to pain Hyperesthesia includes both allodynia and hyperalgesia Hyperpathia is defined as a painful syndrome characterized by an...
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Báo cáo y học: "Invasive pulmonary and central nervous system aspergillosis following slops aspiration in a trauma patient" pot
... coccidioidomycosis with caspofungin and fluconazole BMC Infect Dis 2006, 6:26 doi:10.1186/cc9228 Cite this article as: Zhang M, et al.: Invasive pulmonary and central nervous system aspergillosis following ... Kontoyiannis DP, Marr KA, Morrison VA, Segal BH, Steinbach WJ, Stevens DA, van Burik JA, Wingard JR, Patterson TF; Infectious Diseases Society of America: Treatment of aspergillosis: clinical practice ... pulmonary contusion was shown on day Black arrows, multiple lesions of fungus infection in both the lung and the brain White arrows, progression of encephalomalacia in the left frontal lobe Lin...
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Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf
... [7], although kinetic studies [8] indicate that its alanineglyoxylate aminotransferase activity is not favored over aminobutyrate-pyruvate, b-alanine-pyruvate and dimethylarginine-pyruvate aminotransferase ... (p97) cofactor (p47) Aminoacylase Phosphoglycerate mutase Indolethylamine N-methyltransferase Peroxiredoxin Apolipoprotein A- I Abhydrolase domain containing 14b D-Amino Protein name ApoA4 ActB ... version 5.0 software (GeneBio, Geneva, Switzerland), including spot detection, quantification, normalization, data analysis and statistics Comparative analysis of protein spots was performed by matching...
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Gene expression changes in the brainstem and prefrontal cortex in a mouse model of orofacial pain
... microarray-based approaches to examine gene expression and miRNA changes in the brainstem and prefrontal cortex in a mouse facial carrageenan injection model of orofacial pain At the brainstem level, increased ... Inflammatory pain Tissue injury initiates an inflammatory response that induces pain This type of pain is known as inflammatory pain Inflammatory pain is due mainly to the action of prostaglandins ... demonstrated the involvement of both brainstem and prefrontal cortex in pain, in a mouse model of orofacial pain The differentially expressed genes in different region of the brain i.e brainstem and...
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Effects of central nervous system free fatty acids, prostaglandins and lysophospholipids on allodynia in a mouse model of orofacial pain
... infection and neoplasms Neuralgic pain is generally expressed in the facial area as idiopathic trigeminal neuralgia The ill-defined category of atypical oral and facial pain includes a variety of pain ... hyperalgesia, and in the area of normal tissue surrounding the injury site, as secondary hyperalgesia (c) Phase (Neuropathic Pain) These are abnormal pain states and are defined as pain initiated or caused ... have also indicated central involvement of excitatory amino acids in trigeminal nociception (Parada et al., 1997) Methods of Assessing Pain in Animals Pain research and therapy during the past...
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Báo cáo y học: "Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender" pdf
... independent of gender, age and energy intake The design of our study (Table 1) provided the opportunity to establish whether each region of the CNS exhibits a unique pattern of gene expression Gene expression ... analysis of the effects of aging, CR and gender on gene expression in tissues throughout the body Here we report the results of the CNS component of AGEMAP in which the expression levels of 16,896 ... 27% of the genes that were significantly affected by age changed between young and middle age, and then returned to the young level in old age On the other hand, we found that it was extremely...
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Báo cáo khoa học: "Central nervous system Toll-like receptor expression in response to Theiler''''s murine encephalomyelitis virus-induced demyelination disease in resistant and susceptible mouse strains" ppsx
... Theiler's 3murine encephalomyelitis virus elements in the central nervous system of SJL/J and C57BL/6 mice after infection with Expression of Toll-like receptors for viral Expression of Toll-like receptors ... multiple TLRs in the mouse brain and in TMEV-infected microglia[3,4] This could support the direct or indirect (by the induction of cytokines and chemokines) involvement of TLRs in the initiation ... Theiler's Toll-likeencephalomyelitis virus elements in the central nervous system of SJL/J and C57BL/6 mice after infection Expression Expression of Toll-like receptors for bacterial elements in the...
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Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka N, Itoh K, Harada M, Todo S: Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil ... cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage ... vaccination with mGC8 cells and GM-CSF T cells generated from TVDLN at day nine after vaccination were polyclonally activated and expanded as described in the Methods section and tested for tumorspecific...
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báo cáo hóa học: " CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson’s disease" pot
... were obtained from a rat brain atlas by Paxinos and Watson The injection was made at a rate of μl/ using a 10 μl Hamilton syringe with a 26-gauge needle At the end of each injection, the syringe ... Contralateral rotation measurements following administration of apomorphine in each experimental group are shown in bar graph at days and 21 days post-6-OHDA injection Data are presented as mean ... rTNF -a and 20 pg/ml for rIL-6) Three animals per group were analyzed and each sample was analyzed in duplicate Statistical analysis Statistical analysis of the data was performed using GraphPad...
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Báo cáo y học: "Spectrocolorimetric assessment of cartilage plugs after autologous osteochondral grafting: correlations between color indices and histological findings in a rabbit model" ppt
... regenerated, hyaline cartilage or fibrocartilage? Non-invasive ultrasonic evaluation of tissueengineered cartilage Rheumatology 2004, 43:1106-1108 Laasanen MS, Töyräs J, Vasara A, Saarakkala S, Hyttinen ... were averaged for each cartilage measurement Previously, we determined the standard L*, a* and b* values and the standard spectral reflectance ratio of intact articular cartilage in Japanese ... qualitative and quantitative T2 mapping was useful for differentiating hyaline cartilage from reparative fibrocartilage after cartilage repair using 1.5T MRI Using optical coherence tomography,...
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Báo cáo y học: "Prospective evaluation of serum biomarker levels and cartilage repair by autologous chondrocyte transplantation and subchondral drilling in a canine model" pps
... normal repaired cartilage tissue; D2, D4, and D5 show nearly normal results; and D3 showed abnormal repair, with 50% filling of repaired cartilage and approximately half of the repaired cartilage ... participated in operative anesthesia and preoperative and postoperative animal care JS and NP participated in pathological and radiological interpretation SL participated in statistical analysis ... from the autologous chondrocyte transstaining plantation group (hematoxylin and eosin) demonstrates a cellular arrangement, (b) and glycosaminoglycan-containing extracellular matrix, which has been...
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Báo cáo y học: "Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus" doc
... frequently employ autoantigen microarrays as a screening tool to identify autoantibody reactivities using a multiplex platform and rely heavily on statistical algorithms to determine significant differences ... TLR inhibitors are already being tested in SLE in early-phase human clinical trials Our studies provide a crucial link between the IFN -I system and TLR signaling in vivo and suggest that IFN -I is ... the study idea and participated in its design, data analysis, and the writing of the manuscript All authors read and approved the final manuscript Available online http://arthritis-research.com/content/11/4/R112...
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Báo cáo y học: "Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia–reperfusion" pot
... Critical Care February 2005 Vol No Van Putte et al high mortality rate for the patient Some causes of warm ischemia–reperfusion injury are cardiopulmonary bypass during cardiac surgery and pulmonary ... 30 to hours of reperfusion in a model of acute lung injury, which was defined by quantifying apoptosis and alveolar oedema R2 Materials and methods Animals Male inbred Wistar rats (mean weight ... known as ARDS Clinical ARDS is characterized by acute hypoxemic respiratory failure due to non-cardiogenic pulmonary oedema caused by increased permeability of the alveolar capillary barrier,...
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Báo cáo khoa học: "Effects of dopexamine on the intestinal microvascular blood flow and leucocyte activation in a sepsis model in rats" pptx
... microcirculation) and reduced leucocyte activation (a marker of inflammation) in experimental sepsis Key messages • Dopexamine improved intestinal microvascular blood flow in a sepsis model in rats • Dopexamine ... the aim being to maintain adequate oxygen delivery to all organs and to the gut in particular In addition to noradrenaline (norepinephrine), adrenaline (epinephrine), dopamine and dobutamine, dopexamine ... elucidate the effects of dopexamine in clinical sepsis, additional studies in patients are required Conclusion The administration of dopexamine improved IMBF and FCD (markers of intestinal microcirculation)...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ