Microfluidic study of plasticity in pancreatic beta cell heterogeneity

... paralleling its insulin release profile (See section 3.5.2 Glucose-induced quinacrine secretion in -TC-6.) As such, staining the cells with quinacrine would allow us to probe the intracellular insulin ... in developing a microfluidic competition assay as an alternative method of studying equilibrium binding events A method for determining the various binding constants, as well as for...

Ngày tải lên: 14/09/2015, 08:42

... investigated the effects of prolonged exposure to sulfonylurea drugs on beta cell metabolism using a combination of different NMR techniques, and utilizing the well-characterized clonal glucose-responsive ... ours, in that they focused on the effects of acute sulfonylurea exposure, whereas we examined the effects of prolonged exposure on ATP levels u...

Ngày tải lên: 30/03/2014, 10:20

... eliminate the glycerol-phosphate shuttle), when the malate-aspartate shuttle was blocked by inhibiting aspartate aminotransferase by aminooxyacetate, glucose- induced increases in cellular ATP content ... fatty acid concentration During starvation homeostatic mechanisms attempt to maintain a minimal acceptable blood glucose concentration, in part to maintain neurons that cannot u...

Ngày tải lên: 13/08/2014, 16:20

... COD and Alkalinity A composite wastewater sample was subjected to treatability study by means of coagulation-flocculation with alum and chemical oxidation with bleaching powder [Ca(OCl)2] separately ... discharge standard for inland water body Materials and methods 2.1 Manufacturing process of the textile dyeing unit The textile dyeing unit under the present study...

Ngày tải lên: 05/09/2013, 17:03

... The Comparative Study of Insults in Vietnamese and American English aimed at providing Vietnamese users of English and American users of Vietnamese with some knowledge about social factors influencing ... being female 3.3 DATA ANALYSIS METHODS First, all the Vietnamese data and the American data were tabulated separately Second, the trends in each group...

Ngày tải lên: 26/11/2013, 13:16

... understatements in editorials in English and Vietnamese newspapers 4 1.2.2 Objectives • Identifying understatements in editorials in English and Vietnamese newspapers • Analyzing the syntactic, pragmatic and ... features of understatement in editorials in English and Vietnamese newspapers? What are the differences and similarities of unde...

Ngày tải lên: 26/11/2013, 13:19

... understand and individuals and groups using in sports language through collocations of words and it will We have found that learning to analyze and interpret the collocation of words in the language ... whole of the English language, - To point out of the collocational errors in the language of sports between English and Vietnamese as...

Ngày tải lên: 26/11/2013, 13:19

... using metaphor in teaching, learning, translating, writing and reading of English and Vietnamese newspapers The findings of study on similarities and differences Chapter LITERATURE REVIEW AND ... between metaphors They are structural metaphors, orientational metaphors and metaphor and metonymy Lakoff and Johnson in Metaphor We Live By ontological metaphors (1980) explain met...

Ngày tải lên: 26/11/2013, 13:25

... realized in In reality, the contrastive study on the syntactic and pragmatic English and Vietnamese We have described and analysed the features of CEs in English and Vietnamese will help learners have ... in English and Vietnamese CHAPTER CONCLUSIONS AND IMPLICATIONS 5.1 A SUMMARY OF THE STUDY After selecting and classifying the data into categories t...

Ngày tải lên: 26/11/2013, 13:26

... editorial dramadoc infomercial infotainment magalogue televangelist animatronics camcorder rockumentary Dramatized+ documentary Television+ commercial information + entertainment magazine + catalogue ... relative to their grapheme and phonetic lengths in both ways of analysis He used a corpus of blends to check This corpus is already one of largest available.containing at least 98...

Ngày tải lên: 14/12/2013, 00:41

... difficulties in learning the listening skill in the Asemlink of international languages center it is better to base on the study 3.2.3 Study of teaching and learning the English listening skill in the Asemlink ... experiences, the author would like to a research titled A Study of Difficulties in Learning English Listening...

Ngày tải lên: 14/12/2013, 00:41

... from the central to the southern areas of Laos In this part of the report, we seek to understand the context of land concessions in Laos, including the development of the meaning of “land”, the ... sector22 (in Hat Yao), before the expansion of rubber into the other regions of the country In this sense, the history of the beginning of rub...

Ngày tải lên: 21/02/2014, 04:20

... conformational ¯exibility We not consider the rheomorphic state of a Caseins, synucleins and tau as rheomorphic proteins The ROA data clearly show the caseins, synucleins and tau to have similar ... caseins, synucleins and tau (Eur J Biochem 269) 155 CONCLUSIONS This study has shown that the casein milk proteins, the brain proteins synuclein and...

Ngày tải lên: 21/02/2014, 15:20

Ngày tải lên: 08/03/2014, 14:20

... et al (2005) A microRNA polycistron as a potential human oncogene Nature 435, 828–833 39 Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y & Takahashi ... this approach discriminates normal and neoplastic tissues in various cancer types, including CLL, breast cancer, glioblastoma, thyroid papillary carcinoma, hepatocellular carcinom...

Ngày tải lên: 16/03/2014, 01:20