Context dependent DNA substitution models

... Codon substitution models Context dependent substitution models 10 1.4.1 1.4.2 1.5 Context dependent model at the nucleotide level 11 Codon context substitution ... general context dependent substitution model 27 substitution of b, we look for the substitution matrix Qa,c Totally, we define 16 context dependent Q matrices The model of 16 context dependent...

Ngày tải lên: 14/09/2015, 08:41

... a word translation model and a bigram language model The bi-gram language model was generated by using CMU LM toolkit (Clarkson et al., 1997) Instead of using a fertility model, we allowed a ... dependency problem, we utilize bilingual verb-noun collocations that are automatically acquired from the chunk-aligned bilingual corpora 4.1 step Filter out reliable bilingual verb...

Ngày tải lên: 20/02/2014, 15:20

... mutants of the yeast protein confirms this We have explored the context-dependent effects of proline on ubiquitin stability by introducing a number of substitutions at positions P37 and P38 The equilibrium ... region (residues 21–35) N terminal to the X37 and X38 mutation sites, and the sequence of the short helix (residues 38–40) and fourth strand of...

Ngày tải lên: 07/03/2014, 16:20

... requires protein translocation to the nucleus Although functional analyses of individual domains have not been addressed, the global context of the domain analyses allows us to draw a more general ... 0.75 are shown Black geometrical shapes are additional domains, as indicated ANOGA, Anopheles gambiae; ASHGOS, Ashbya gossypii; BRARE, Brachydanio rerio; CANDGLA, Candi...

Ngày tải lên: 07/03/2014, 21:20

... different credit risk models leading to the same multivariate distribution of S or Y Since this distribution is the main object of interest in the analysis of portfolio credit risk, we call two models ... “Copulas and Credit Models, ” Giesecke, K (2001): “Structural modelling of defaults with incomplete information,” preprint, Humboldt-Universit¨t Berlin, forthcomin...

Ngày tải lên: 15/03/2014, 04:20

... edges of π and alignments Each node of the graph is labeled with its span and complement span (the latter in italic in the figure) The span of a node n is defined by the indices of the first and last ... possible ways of attaching to constituents of π: besides the highest attachment (rule (f)), can move along the ancestors of France, since it is to the right of the transla...

Ngày tải lên: 17/03/2014, 04:20

... techniques to collect entities and descriptions from a corpus and analyzed their lexical and semantic properties We have processed 178 MB of newswire and analyzed the use of descriptions related to ... PROFILE (Radev and McKeown, 1997) It turns out that there is a large variety in the size of the profile (number of distinct descriptions) for different entities Table s...

Ngày tải lên: 17/03/2014, 07:20

... intensity of the GlnB band was quantied as the sum of the concentrations of GlnB and GlnK and was denoted by PII* Note that PII* includes the modied forms of GlnB and GlnK as well, i.e GlnBUMP and ... bars indicate the SEM The dotted line is a result of two linear regression ts of the data points The extra abscissa on top of the gure indicates...

Ngày tải lên: 23/03/2014, 04:21

... arguments to the left Using these rules, we can parse the following phrase: flights to boston N λx.f light(x) (N \N )/N P λy.λf.λx.f (x) ∧ to( x, y) NP boston (N \N ) λf.λx.f (x) ∧ to( x, boston) > ... other feature weights were initially set to zero 11 Conclusion In this paper, we addressed the problem of learning context-dependent mappings from sentences to logical form W...

Ngày tải lên: 23/03/2014, 16:21

... each context The question of how to achieve a good trade-off thus becomes the main consideration for various context dependent modelling 1.3 Context- Dependent Acoustic Modelling schemes For the ... neighbouring contexts Table 1.1 shows several types of context dependent models for the phrase “go to”: Table 1.1: Context modelling with different context lengths...

Ngày tải lên: 09/09/2015, 11:07

... new models, compared with the experimental values (w and z ) for resting and primed aIIbb3 [10] As seen, the fully bent and partially extended models of the resting integrin ... rotation of the bTD module at the main chain of D606 to dock it against the calf-2 domain with its C-terminus in proximity of the N-terminus of the b3 open TM helix Overall evaluation of the...

Ngày tải lên: 18/02/2014, 04:20

... PGM4 targets) Effects of DNA cis-platination on sequencespecific DNA binding of p73 proteins We tested the in uence of DNA modification with cisplatin on the binding of two p73 isoforms, p73d and p73b, ... DNA binding to DNA treatment with cisplatin and the ability of the particular p53 target site to accommodate the cisplatin IACs The higher...

Ngày tải lên: 19/02/2014, 05:20

... supports the view that the DNAPKcs -mediated aggregates stay in a catalytically competent state A further concern is whether the protein kinase activity of DNA- PKcs is really associated with the EJ ... types of DNA in a Mg2+-dependent manner This preference is conditional since supercoiled DNA was aggregative in the absence of Mg2+ These results suggest that...

Ngày tải lên: 19/02/2014, 06:20

... the DNA binding activity of dHAND could be affected by Akt phosphorylation The influence of phosphorylation by Akt on the DNA binding activity was examined by gel shift analysis We included the ... that phosphorylation of these sites might affect the DNA binding and/or dimerization activities of dHAND We first analyzed the effect of phospho...

Ngày tải lên: 07/03/2014, 16:20

... statistical machine translation In Proc of ACL, pages 160–167 K Papineni, S Roukos, T Ward, and W.-J Zhu 2002 BLEU: a method for automatic evaluation of machine translation In Proc of ACL, pages ... Chiang, K Knight, and W Wang 2009 11,001 new features for statistical machine translation In Proc of NAACL, pages 218–226 M Riedmiller and H Braun 1993 A direct adaptive method...

Ngày tải lên: 07/03/2014, 22:20