Characterization of murine soluble CD137 and its biological activities

... Detection of soluble CD137 and CD137L complexes 65 Figure 19 Determination of the binding of soluble CD137 to recombinant CD137L 67 Figure 20 Determination of the binding of soluble CD137 to ... membrane-bound CD137 Levels of soluble CD137 correlate with activation induced cell death and depletion of soluble CD137 results in increase of IL-10 and IL...

Ngày tải lên: 12/09/2015, 09:55

... We interpret this observation as the retainment of newly synthesized proteins in the cytosol due to the inability to import matrix proteins by the fraction of growing and dividing glycosomes The ... lower (not shown) In order to determine the in uence of the reduction of the expression of TbPEX14 on the import of glycosomal matrix proteins,...

Ngày tải lên: 23/03/2014, 17:21

... these questions using a strategy of single amino acid site-directed mutagenesis Delineation of ExoS residues of the cofactor interaction domain within ExoS Various single mutant ExoS proteins ... study study study study study 639 Delineation of ExoS residues L Yasmin et al Fig Interaction of GST-ExoS variants with endogenous 14-3-3 proteins HeLa cells were harveste...

Ngày tải lên: 19/02/2014, 08:20

... Photobiont (21.67) Table Comparative n- alkane and fatty acid compositions of X parietina, the photobiont Trebouxia sp., and the mycobiont (% of total n- alkanes) collected in the places indicated ... the presence of alkanes, and found that the main ones were C27, C29 and C31 The alkanediene C17H32 and normal alkanes in the C9–C17 range, with the...

Ngày tải lên: 23/03/2014, 17:21

... were eluted in two phases with 300 mL of linear gradient of 0–0.6 M NaCl and 50 mL of linear gradient of 0.6–1 M NaCl at a flow rate of 0.8 mLÆmin)1 Fractions of mL were collected and those displaying ... results of studies leading to the conclusion that at least two distinct soluble enzymes of P denitrificans exhibit an activity of Fe(III) reductase These enzymes...

Ngày tải lên: 30/03/2014, 13:20

... CHARACTERIZATION OF THE SECRETION OF MESENCHYMAL STEM CELLS AND ITS RELEVANCE TO CARDIOPROTECTION LAI RUENN CHAI (B.Eng (Hons.)), NTU A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... identified Thesis The specific aims of this PhD project were to identify the active cardioprotective factor of the MSCs secretion and to elucidate t...

Ngày tải lên: 10/09/2015, 08:42

... acidic proteins (Hathaway and Traugh, 1982) Two distinct casein kinases have been found in many different cell types They have been designated casein kinase (CK1) and casein kinase (CK2) according ... Ca2+/calmodulin-dependent protein kinase II cAMP cyclic adenosine monophosphate Cdk cyclin-dependent kinase Cdk5 cyclin-dependent kinase cDNA complementary deoxyribonucleic a...

Ngày tải lên: 16/09/2015, 17:10

... downstream of Busan area of Nakdong river basin Estrogenic activity and concentration of estrogenic substances in the Nakdong River basin Relative estrogenic activity of the main and branch stream of Nakdong ... substances and activity is distributed over the whole middle and downstream excluding the upstream of Andong Relative estrogenic activ...

Ngày tải lên: 05/09/2013, 08:40

... Making an investigation of some semantic and pragmatic features of the adjective Warm in English and its equivalents in Vietnamese - Analyzing meanings of the adjective Warm in particular contexts, ... discover, analyze and contrast Some linguists have studied of adjectives as well as semantic and pragmatic characteristics of the adjective Wa...

Ngày tải lên: 26/11/2013, 13:21

... Gevaert et al COFRADIC and protein modifications analysis of purine-binding proteins in a total lysate of human Jurkat T-cells [40] primary separation mAU 1400 COFRADIC analysis of protein processing ... [34,36] and N-glycosylation [39] – and describe the use of COFRADIC for studying interactions between small molecules and proteins The latter is a particular applicatio...

Ngày tải lên: 18/02/2014, 16:20

... a biphasic loss of activity (Fig and Table 3) The phenotype of these substitutions is therefore different from that of N139A, T146A and W141A The F residues at positions 100 and 128 are highly ... incubation for 40 The specific inhibitory activity of PAI-1 at the various timepoints, i.e the fraction of the total amount of PAI-1 forming a stable complex with...

Ngày tải lên: 20/02/2014, 11:20

... include Gilboa and Schmeidler (1989), Epstein and Wang (1994), Anderson, Hansen, and Sargent (2000), Chen and Epstein (2002), Hansen and Sargent (2001), Epstein and Miao (2003), Routledge and Zin (2002), ... Liu and Pan (2003), Liu, Longstaff, and Pan (2003) and Das and Uppal (2001) Dufresne and Hugonnier (2001) study the impact of event risk on pricing and hedging...

Ngày tải lên: 07/03/2014, 10:20

... objective of understanding how the glycolytic ux in E histolytica is controlled, we cloned the genes, and overexpressed, puried and determined the kinetic parameters of the 10 glycolytic enzymes ... reconstruction of the nal stages of amoebal glycolysis Analysis of the kinetic properties of the recombinant glycolytic enzymes indicated that EhPPDK and EhPG...

Ngày tải lên: 07/03/2014, 17:20

... 16a-hydroxyprogesterone Both expressed enzymes had no lyase activity towards PROG or 17-OHPROG Understanding of the complexity of hydroxylase and lyase activity of CYP17 by way of primary sequence ... the metabolism of PREG by the two enzyme preparations Despite the large degree of homology between the human and baboon CYP17 the expressed baboon CYP17 was una...

Ngày tải lên: 08/03/2014, 09:20

... haemagglutinin at the C-terminus and encoding the cathepsin D propeptide fused to mature cathepsin E, we have demonstrated that the propeptide of cathepsin E, likewise those of other aspartic proteinases, ... maturation of cathepsin E, we constructed a mutant lacking the propeptide (Leu23-Phe58) and expressed it in HEK -293T cells The transfected cells were pul...

Ngày tải lên: 16/03/2014, 14:20