Biointormatics of targeted therapeutics and applications in drug discovery

Biointormatics of targeted therapeutics and applications in drug discovery

Biointormatics of targeted therapeutics and applications in drug discovery

... Bioinformatics of Targeted Therapeutics and Applications in Drug Discovery x Bioinformatics of Targeted Therapeutics and Applications in Drug Discovery List of Tables Chapter Table Statistics of ... multi-target drugs and drug combinations, which are more efficacious and vii Bioinformatics of Targeted Therapeutics and Applications in Drug...

Ngày tải lên: 12/09/2015, 09:10

232 496 0
Báo cáo hóa học: " Research Article Remarks on Separation of Convex Sets, Fixed-Point Theorem, and Applications in Theory of Linear Operators" pot

Báo cáo hóa học: " Research Article Remarks on Separation of Convex Sets, Fixed-Point Theorem, and Applications in Theory of Linear Operators" pot

... functional f which separates K0 and K1 In a linear topological space, any two disjoint convex sets, one of which has an interior point, can be separated by a nonzero continuous linear functional, ... convex norm, we may prove (under certain general conditions) certain generalizations of the results on separation of convex sets Theorem 2.6 Let K0 and K1 be disjoint...

Ngày tải lên: 22/06/2014, 19:20

14 314 0
7Microbial Enzymes in the Biocontrol of Plant Pathogens and aEnzymes in the Environment: Activity, Ecology and Applications - Chapter 7PestsLeonid Chernin and Ilan ChetThe ppt

7Microbial Enzymes in the Biocontrol of Plant Pathogens and aEnzymes in the Environment: Activity, Ecology and Applications - Chapter 7PestsLeonid Chernin and Ilan ChetThe ppt

... attachment, and de novo synthesis of a set of cell-wall-degrading enzymes that aid the parasite in penetrating the host and completing its destruction Lectins, the sugar-binding proteins or glycoproteins ... inhibited in all chitin-containing fungi The degree of inhibition was proportional to the level of chitin in the cell wall of the target fungus Combini...

Ngày tải lên: 11/08/2014, 15:20

56 675 1
Báo cáo y học: "Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications" ppsx

Báo cáo y học: "Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications" ppsx

... development and application of non invasive in vivo methodologies to the study of biological structure, function and xenobiotic response in STII medaka The development of this in vivo investigatory "system" ... study of piscine biliary transport Collectively these findings demonstrate the ability to study, with high resolution, normalcy and disease/toxicity i...

Ngày tải lên: 13/08/2014, 13:20

26 447 0
In silico methodologies for selection and prioritization of compounds in drug discovery

In silico methodologies for selection and prioritization of compounds in drug discovery

... filter, score and rank structures of compounds using in silico methods Virtual screening may be used to select and prioritize compounds for screening in assays, 19 selecting which compounds to ... supervised learning and unsupervised learning Supervised learning involves the deduction of a function from training data The training data typically consist of vectors of...

Ngày tải lên: 08/09/2015, 22:12

185 380 0
Computational study of therapeutic targets and ADME associated proteins and application in drug design

Computational study of therapeutic targets and ADME associated proteins and application in drug design

... process of drug discovery - VI - Computational study of therapeutic targets and ADME- associated proteins and application in drug design List of Tables LIST OF TABLES Table 1-1: A brief history of ... pharmacogenetic prediction of drug responses 159 - VII - Computational study of therapeutic targets and ADME- associated proteins and...

Ngày tải lên: 15/09/2015, 22:19

187 1,1K 0
Development of novel positively charged single isomer cyclodextrins and applications in enatiomeric separation and chiral synthesis 1

Development of novel positively charged single isomer cyclodextrins and applications in enatiomeric separation and chiral synthesis 1

... Chapter Synthesis of positively charged single- isomer cyclodextrins 33 Approached for cyclodextrins 33 2 Synthesis of single- isomer positively charged cyclodextrins 37 2 Synthesis ... ability of β-CDNH2 11 0 Effect of pH and CD concentration on EOF 11 1 Effect of pH on migration times 11 2 3 Effect of pH on enantioseparation of acid analytes ……...

Ngày tải lên: 16/09/2015, 08:30

11 181 0
Development of novel positively charged single isomer cyclodextrins and applications in enatiomeric separation and chiral synthesis

Development of novel positively charged single isomer cyclodextrins and applications in enatiomeric separation and chiral synthesis

... Structures of 21 positively charged single- isomer CDs 37 2 Synthesis of positively charged single- isomer cyclodextrins All mono-substituted positively charged CDs are prepared according to the ... above, the key aim of this project focuses on the development of a novel family of positively charged single- isomer CDs and their application in the...

Ngày tải lên: 16/09/2015, 08:30

187 441 0
Three applications of economic theory and methodology in information systems research

Three applications of economic theory and methodology in information systems research

... in the field of IS can be solved using the theory and methodology of economics In this thesis, three IS research problems: competition and compatibility between open source and proprietary software, ... deployment, and management of information technology resources and services (the information systems function), and (2) development and evolution of inf...

Ngày tải lên: 16/09/2015, 08:30

131 1,3K 0
In vivo aspects of potential stereospecific drug interactions of oral warfarin and rutin in rats

In vivo aspects of potential stereospecific drug interactions of oral warfarin and rutin in rats

... activity of the drug But metabolite estimation helps in understanding the source of variation and mechanism of interaction of drugs with warfarin A better understanding of the warfarin drug interactions ... Mean S- warfarin curve fitting for (a) control and (b) rutin treated rats using WinNonlin 71 4.3 Mean R- warfarin curve fitting for (a) control and (b)...

Ngày tải lên: 09/10/2015, 11:24

134 407 0
Representation of nonnegative Morse polynomial functions and applications in Polynomial Optimization

Representation of nonnegative Morse polynomial functions and applications in Polynomial Optimization

... KG , each lying in the interior of KG Then f ∈ TG Proof The proof follows from Theorem and Theorem Applications in polynomial Optimization 4.1 Unconstrained polynomial Optimization In this section ... vectors in Zn of the form λw, λ > Denote by F(Γ ) the family of primitive vectors supporting some face of Γ of dimension n − Representation of Morse polynomi...

Ngày tải lên: 14/10/2015, 08:30

15 317 0
Some aspects of American culture and society in the twentieth and twenty-first centuries through a number of selected short literary works

Some aspects of American culture and society in the twentieth and twenty-first centuries through a number of selected short literary works

... society of the mainstream American in the twentieth and twenty-first centuries such as individualism, American informality, racial discrimination, modern American women, generation gap and American ... economy as the United States of America has become the leading power of the world, and especially witnessed dramatic changes in American society a...

Ngày tải lên: 07/11/2012, 15:01

49 785 1
Investigation on K2Ti4O9 Whisker Absorbent and Applications in Heavy Metal Ions Removal

Investigation on K2Ti4O9 Whisker Absorbent and Applications in Heavy Metal Ions Removal

... increases, which results in more metallic ions absorbed and less ions remain in water in equilibrium, showing as the removal of metallic more ions In the mean time, as the ion content in water decreases, ... or honeycomb, of PTW by mixing and calcining with a suitable binder material Research in this area is being done in Shandong University ACKNOWLEDGMENT This resea...

Ngày tải lên: 05/09/2013, 09:38

6 437 0
A contrastive analysis of metaphorical lexis and collocation in english and vietnamese economics discourse

A contrastive analysis of metaphorical lexis and collocation in english and vietnamese economics discourse

... Some analyses of metaphorical lexis and collocation in English and Vietnamese economics discourse The study involved analysing economics texts in English and Vietnamese for their use of metaphor ... conceptualised as objects that move up and down, through lexis such as rising and falling, soaring and plummeting, edging up and slipping back 10 Lakoff...

Ngày tải lên: 07/09/2013, 12:58

33 1,1K 3
A cross cultural study of giving compliments and responses in english and vietnamese

A cross cultural study of giving compliments and responses in english and vietnamese

... “Communication is, rather, the successful interpretation by an addressee of a speaker’s intent in performing a linguistics act” (Georgia M Green, Natural Language Understanding, p.1) And a linguistics ... data that reveal the cultural orientation of language learners (In many languages, compliment responses require the language user to walk a delicate line between appearin...

Ngày tải lên: 14/12/2013, 00:41

15 5K 72
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