Mutational analysis of the TATA binding protein (TBP) in sac

Mutational analysis of the TATA binding protein (TBP) in saccharomyces cerevisiae

... ubiquitin attached to Protein X and the Cterminus to Protein Y and the reporter RUra3p 47 Figure 2.8 Interaction between Protein X and Protein Y Interaction of the two proteins brings about the ... able to interact with TFIIF more rapidly, resulting in strong activation of transcription (Choi et al., 2003) 2.5.1.3 TFIID /TATA- Binding Protein The TATA- binding...

Ngày tải lên : 12/09/2015, 08:20

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Báo cáo khoa học: Conformational and functional analysis of the lipid binding protein Ag-NPA-1 from the parasitic nematode Ascaridia galli potx

... like the Trp residue of the 183 Conformation, ligand binding and distribution of nematode protein Ag-NPA-1 R Jordanova et al Fig Immunohistological localization of Ag-NPA-1 in adult A galli and ... ligand binding and distribution of nematode protein Ag-NPA-1 Fig Immunogold electron microscopic localization of Ag-NPA-1 in a male A galli worm (A) Sect...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA pot

... Supercoil binding by topoisomerase I Fig Human topoisomerase I fragments used in the DNA -binding studies (A) The four domains of full-length human topoisomerase I (topo I) are shown above the various ... supercoiled DNA is unknown but, if node recognition is important, then it is likely that the binding involves an interaction with two regions of DNA...

Ngày tải lên : 29/03/2014, 22:21

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Báo cáo khoa học: Functional analysis of the aglycone-binding site of the maize b-glucosidase Zm-p60.1 pot

... and catalytic properties of the mutants, and simulations of the substrate–enzyme interactions of the wild-type and one of the mutants The results provide indications of the native enzymes’ catalytic ... construction of the mutant b-glucosidases Findings that cytokinin-O-glucosides are natural substrates for both of the two b-glucosidases, Zm-p60.1 and Bgl4:1, b...

Ngày tải lên : 16/03/2014, 04:20

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Báo cáo khoa học: Role of CCP2 of the C4b-binding protein b-chain in protein S binding evaluated by mutagenesis and monoclonal antibodies docx

... amounts of ﬂuid phase protein S on the binding of the MoAbs to immobilized recombinant b-chain was tested The binding of both MoAb 15 and MoAb 44 to the b-chain was Ó FEBS 2003 The role of CCP2 of ... protein S and MoAb 44 Discussion The binding site for protein S on C4BP is predominantly contained in CCP1 of the b-chain [9] A key b...

Ngày tải lên : 17/03/2014, 09:20

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Báo cáo khoa học: Mutational analysis of the C-domain in nonribosomal peptide synthesis pot

... in the study of peptide synthetases was the determination of the A-domain structure of GrsAPhe-A [8] Aspects of speci®city and binding were superimposed on other A-domains and with the help of ... bound in the binding pocket of another enzyme molecule within the active homomultimer This could explain the distance in sequence homology with NRPSs C-domains disp...

Ngày tải lên : 17/03/2014, 11:20

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Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt

... 5357 an anabolic stimulus, may largely induce increased translation across the board of mRNAs that are already actively being translated How could increased phosphorylation of eIF4E actually inhibit ... i.e has a cap and a poly (A) -tail The open reading frame of the mRNA is shown as a thick line Initiation factors are abbreviated The arrow indicates the phosphory...

Ngày tải lên : 23/03/2014, 21:20

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Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt

... this article as: Ehlén et al.: Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer Journal of Translational ... http://www.translational-medicine.com/content/8/1/78 Page of 12 Figure Expression of RBM3 in the cisplatin- sensitive A2 780 ovarian cancer c...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo sinh học: "Mutational analysis of the potential catalytic residues of the VV G1L metalloproteinase" pptx

... Figure (A) Alignment of the VV G1L putative catalytic domain with the catalytic domain found throughout MMPs (A) Alignment of the VV G1L putative catalytic domain with the catalytic domain found ... wild type G1L In no other case did rescue reach above 25% of wild type The role of both the full-length and cleaved products of VV G1L continue to be in...

Ngày tải lên : 19/06/2014, 08:20

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báo cáo hóa học:"Mutational analysis of the potential catalytic residues of the VV G1L metalloproteinase" docx

... Figure (A) Alignment of the VV G1L putative catalytic domain with the catalytic domain found throughout MMPs (A) Alignment of the VV G1L putative catalytic domain with the catalytic domain found ... wild type G1L In no other case did rescue reach above 25% of wild type The role of both the full-length and cleaved products of VV G1L continue to be in...

Ngày tải lên : 20/06/2014, 04:20

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Báo cáo y học: " Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins" ppt

... to analyse any differences between the PDZ- binding activities of the human and avian NS1 proteins A PDZ array assay had previously been reported, using a large number of isolated PDZ domains, and ... Human (H) NS1, together with the non -PDZ- binding mutant of Avian NS1 (Aa), plus the avian human-like (Ah) and the human avian-like (Ha) mutants Lower panel GS...

Ngày tải lên : 11/08/2014, 21:21

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Báo cáo khoa học: Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution pdf

... Fluorescence studies of RepA R E M Diederix et al Interestingly, in the latter case, the protein binds as a monomer [26] Free in solution, the protein is essentially dimeric, ... DNA-binding domains, and rearrangement of the relative orientation of the two domains [7,9] The conformational change upon iteron binding may expose a recognition site for prote...

Ngày tải lên : 07/03/2014, 04:20

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Báo cáo khoa học: A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells doc

... gene signaling pathway analysis has identiﬁed gene signals that are remarkably activated in AT-MSC-Hepa, and these signals are also up-regulated in whole liver Therefore, the microarray analysis ... protocol, and then treated with deoxyribonuclease (DNase I, ampliﬁcation grade; TaKaRa, Kyoto, Japan) Microarray analysis and data mining (Aligent array) A one-color microarray...

Ngày tải lên : 30/03/2014, 04:20

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Báo cáo khoa học: Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa ⁄ fa rats pptx

... contributes to the hepatic defect in the Zucker fa ⁄ fa rat 1990 Results High activities of glucokinase and phosphorylase in hepatocytes from fa ⁄ fa rats Hepatocytes from fa ⁄ fa rats had a higher total ... overexpression in hepatocytes [26– 28] However, the contribution of these targeting proteins to the increased activity o...

Ngày tải lên : 30/03/2014, 11:20

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Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus inﬂuenzae strain 1003 potx

... Schweda, E.K.H (2001) A new structural type for Haemophilus inﬂuenzae lipopolysaccharide Structural analysis of the lipopolysaccharide from nontypeable Haemophilus inﬂuenzae strain 486 Eur J Biochem ... Hex4 glycoforms were indicated Ó FEBS 2002 Structural analysis of LPS from NTHi strain 1003 (Eur J Biochem 269) 811 Fig Negative ion ESI-MS spectrum o...

Ngày tải lên : 31/03/2014, 21:21

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