Substance p chemokine interaction in mouse pancreatic acinar cells, and its implications in acute pancreatitis

... RANTES and CXC chemokines, IL-8, GRO-α, CINC and MIP-2 are important in acute pancreatitis 1.5.1 Chemokines in Acute Pancreatitis A study of chemokine gene expression in rat pancreatic acinar cells ... is involved in substance P (SP)-induced MCP-1, MIP-1α and MIP-2 secretion 116 4.7 Substance P (SP)/NK1R interaction is involved in PKCδ and MEKK1 activ...

Ngày tải lên: 11/09/2015, 16:06

... microscopy, the cell injury exhibits (i) the presence of acinar- cell ghosts; (ii) vacuolization and swelling of acinar cells or (iii) the destruction of the histoarchitecture of the whole or parts of the ... xv SUMMARY The mechanisms of apoptosis in pancreatic acinar cells and the mechanisms by which induction of acinar cell apoptosis protec...

Ngày tải lên: 11/09/2015, 14:20

... role in pancreatic b-cells The objective of the present study was to investigate the expression and antioxidant effects of PHB in pancreatic b-cells exposed to ethanol Effects of prohibitin in b-cells ... endocytosis and vesicle recycling [53] In summary, we found that PHB is expressed in pancreatic b-cells and increases with oxidative stress...

Ngày tải lên: 29/03/2014, 08:20

... verbalisation in Chinese was observed in Tai (1997) In other words, verbs are more freely deverbalised than nouns denominalised This fluidity between verbal and nominal status of verbs can in theory ... nouns, and the implications this phenomenon might have for POS tagging References Chinese Knowledge Information Processing Group (CKIP) 1993 iirt,=,m,3 }K (EN) Technical...

Ngày tải lên: 08/03/2014, 21:20

... zymogen factor X, activated factor X (factor Xa) and the active site inhibited form DEGR -factor Xa as well as the the factor X peptides were studied with surface plasmon resonance The Ca2+ concentration ... filters Membrane binding experiments on factor X, factor Xa, DEGR -factor Xa and the Gla-containing fragments of factor X were performed with memb...

Ngày tải lên: 08/03/2014, 23:20

... from human T cells in vitro To study the role of C5a on human CD4 + T cells, we used ELISA and intracellular staining to detect cytokine expression PBMCs from AMD patients and controls were treated ... Intracytoplasmic staining of IL-22 and IL-17 from both controls and AMD patients after days of culture with or without C5a and C5aR antagonist Liu...

Ngày tải lên: 18/06/2014, 22:20

... specializations in the brain, indicating that Agrin has a role, at least in part, in maintaining synaptic structure in this tissue [23] In addition, Agrin is expressed at high levels in the brain microvasculature, ... rafts are reviewed in [26]) and of the TCR [25] Interestingly, Agrin from activated T cells induced clustering of acetylcholine receptors when added t...

Ngày tải lên: 12/08/2014, 12:20

... release of VEGF, and the expression and distribution of VEGF and its receptors in the lung during the early onset of ALI induced by intestinal ischemia-reperfusion (IIR), a well-established model of ... is that the increased VEGF is simply the reflection of increased protein leakage in the lung In clinical studies, increased VEGF in plasma [16], and...

Ngày tải lên: 13/08/2014, 03:20

... messages • Increased TREM-1 expression on blood monocytes is an indicator of inflammation but not of infection in patients with AP • Low HLA-DR expression and high IL-6 concentration could predict ... et al Conclusions Increased TREM-1 expression was associated with the presence of inflammation but not infection in AP In patients with AP, low HLA-DR...

Ngày tải lên: 13/08/2014, 16:20

... limitations, the study in Critical Care by Peng and coworkers [1] supports the idea that acute (necrotic/infected) pancreatitis can result in CIRCI following relative adrenal insufficiency, that the ACTH ... interests The author declares that they have no competing interests References Peng Y- S, Wu C-S, Chen Y- C, Lien J-M, Tian Y- C, Fang J-T, Yang C, Chu Y- Y, Hung C-F, Yang C-...

Ngày tải lên: 13/08/2014, 18:22

... survival with recombinant human activated protein C treatment in experimental acute pancreatitis Arch Surg 2006, 141:67 0-6 76 Chen P, Zhang Y, Qiao M, Yuan Y: Activated protein C, an anticoagulant ... protein C) in severe acute pancreatitis Crit Care 2005, 9:32 1-3 22 Bradley EL: A clinically based classification system for acute pancreatitis Summary of the...

Ngày tải lên: 13/08/2014, 21:21

... culture feeding 3.2.3 Human embryonic stem cells and induced pluripotent stem cells Human embryonic stem cell line HES-3 (46, XX) was from ES Cell International (Singapore, http://www.escellinternational.com) ... forebrain, midbrain, hindbrain and the spinal cord This figure was reproduced from Epstein et al., 1999 2.4 SHH and neural development During the initial ph...

Ngày tải lên: 11/09/2015, 10:14

... A-Ng cells … … … … … … 70 x INTRODUCTION Expression and localization of Neurogranin (Ng) 1.1 Neurogranin cloning, homologs and gene structure Neurogranin is a brain specific, postsynaptic protein ... construction and Ng is inserted between HindIII and BamHI - 39 - PCR using primers containing RE sites HindIII adaptor BamHI adaptor Ng cDNA Digestion with HindIII and Di...

Ngày tải lên: 05/10/2015, 22:32

... A-Ng cells … … … … … … 70 x INTRODUCTION Expression and localization of Neurogranin (Ng) 1.1 Neurogranin cloning, homologs and gene structure Neurogranin is a brain specific, postsynaptic protein ... construction and Ng is inserted between HindIII and BamHI - 39 - PCR using primers containing RE sites HindIII adaptor BamHI adaptor Ng cDNA Digestion with HindIII and Di...

Ngày tải lên: 06/10/2015, 20:35