Mitochondrial integrity and antioxidative enzyme efficiency in fischer rats effects of ageing and epigallocatechin 3 gallate intervention 1 3

... also examined the changes of gene expressions of CAT, SOD1, SOD2 and GPx in both young (PDL20 -30 ) and old (PDL >45 ) HDF after 24 hours of treatment with EGCG, since these enzymes are mostly influenced ... expressions both in the young and the old HDF In the young HDF, the gene expressions of CAT, SOD1, SOD2 and GPx increased in response to 25 μM 87 EGCG by 94. 1, 6...

Ngày tải lên: 11/09/2015, 16:05

... listed in Table S cerevisiae C elegans D melanogaster M musculus lag1 daf -2 sod1 prop -1 lac1 age -1/ daf- 23 cat1 p66shc ras2 akt -1/ akt -2 ras1 phb1 daf -16 daf -18 phb2 daf - 12 mth cdc7 ctl -1 mclk1 bud1 ... significant 3. 2 Part two: Effects of epigallocatechin- 3- gallate on mitochondrial integrity and antioxidative enzyme activity in aging process of h...

Ngày tải lên: 11/09/2015, 16:05

... cellular aging studies [16 0, 16 1] The LC50 value of EGCG and its anti- and pro-oxidant effects are examined initially Then in the short term study, HDF is exposed to H2O2 induced oxidative stress and ... 6.25, 12 .5, 25, 50 and 10 0 μM were added into the MEM For the first 30 min, 10 0 μM of EGCG cleared about 32 % free radicals of DPPH but its radical scavenging act...

Ngày tải lên: 11/09/2015, 16:05

... 61 3. 3 .10 Antioxidative enzyme activities .62 3. 3 .11 Antioxidative enzyme gene expressions 62 3. 3 .12 Microarray and data analysis 63 3 .3. 13 Statistics 64 Main results ... activity in Fischer 34 4 rats; Mechanisms of Ageing and Development, 12 8 (3) :286-92 II Meng Q, Velalar CN and Ruan R, (2008); Effects of epigallocatechin- 3- gallate on mitoc...

Ngày tải lên: 11/09/2015, 16:05

... process of HDF reaching the end point, samples were collected, and intracellular ROS accumulation, mitochondrial integrity, antioxidative enzyme activities and gene expressions were examined and ... Effects of EGCG in long term treatment In the long term treatment, the middle-aged HDF (PDL 35) was continuously cultured in MEM with 12 .5 μM of EGCG until they reach...

Ngày tải lên: 11/09/2015, 16:05

... ILMN _6 63 7 5a ILMN_55276e ILMN_5 432 7e ILMN _61 732 e ILMN _65 726e ILMN_49450a ILMN_52 1 36 e ILMN_57 63 0 a ILMN _6 539 0c ILMN_ 537 85e ILMN _64 064 e ILMN_5 268 6c ILMN _6 737 3c ILMN_58243e ILMN _6 63 8 2e ILMN_51 069 e ILMN_59474e ... 2.007 1. 962 1.9 46 1.944 1.9 16 1. 864 1.815 1.784 1 .69 8 1 .68 9 1 .67 5 1 .66 6 1 .66 2 1 .64 5 1. 63 7 1. 63 0 1.577 1. 567 1.558 1.554 1.54...

Ngày tải lên: 11/09/2015, 16:05

... cerebellum of a nitrazepam user at autopsy, and measured nitrazepam and 7-aminonitrazepam both immediately and 10 days (at 4° C) after autopsy as shown in > Table 3.1 Postmortem redistribution of drugs ... in an autopsy case of a digoxin-user Jones and Pounder [25] reported analytical results of imipramine and its metabolite desipramine in blood and various or...

Ngày tải lên: 22/01/2014, 00:20

... functions for right-facing and left-facing instructional conditions The results of a two-way analysis of variance on the positions of the centers of the objects indicate a main effect of facing direction ... pleasing if the subject were positioned decidedly off center and facing out of the frame, violating these conventions to convey feelings of isolation, loneliness,...

Ngày tải lên: 07/03/2014, 17:20

... reaction of 7,8-diols and the enhanced nonbilayer phase propensity in membranes containing PtdEtn Effect of lipids on the stereoselectivity of epoxidation The stereoselectivity of the epoxidation ... redistribution of the substrate between the aqueous and the membrane phase and is brought about by a change in the nonbilayer phase prop...

Ngày tải lên: 08/03/2014, 10:20

... Overview of principles and implementations to deal with spatial issues in monitoring environmental effects of genetically modified organisms Winfried Schröder†1 and Gunther Schmidt*†1 Chair of ... complete monitoring schemes covering approximately 4,000 species and 145 different habitat types and addresses of 239 monitoring coordinators and in...

Ngày tải lên: 20/06/2014, 20:20

... Overview of principles and implementations to deal with spatial issues in monitoring environmental effects of genetically modified organisms Winfried Schröder†1 and Gunther Schmidt*†1 Chair of ... complete monitoring schemes covering approximately 4,000 species and 145 different habitat types and addresses of 239 monitoring coordinators and in...

Ngày tải lên: 21/06/2014, 17:20

... T-cell responses were observed at baseline, in the absence of HIV-1-specific CD4+ T-cell responses, in one patient only Generally, daily administration of rhGH, in the presence of HAART, induced ... lipodystrophy result in a good outcome [45], as well as having beneficial effects on the immune system such as inducing thymocyte differentiation, improving function of l...

Ngày tải lên: 11/08/2014, 10:23

... effects of acetylshikonin on the growth of tumor Inhibitory 3) Inhibitory effects of acetylshikonin on the growth of tumor cells (n = 3) Inhibitory rate on LLC Cyclophosphamide and acetylshikonin ... Figure determined by cell acetylshikonin on (n growth of A549 Inhibitory effects ofgrowth curve assaythe = 3) Inhibitory effects of acetylshikonin on the growth...

Ngày tải lên: 13/08/2014, 15:21

... government and the role of borrower equity in affecting the risk of delinquency and of default; the presence of a significant relationship between delinquency incidence and subsequent default decisions; ... risk models should incorporate the risk of delinquency Among the factors affecting the risk of default and delinquency, the extent of t...

Ngày tải lên: 04/10/2015, 10:26

... determine whether there is correlation of breeding, molting and diet of birds belonging to different feeding guilds, with rainfall and food resources Information on diet changes during breeding and ... the food abundance (i.e arthropods, fruits and flowers), and the frequency of occurrence of breeding and molting in resident understory tropical rainforest bird...

Ngày tải lên: 28/11/2015, 13:44