Patterns of hippocampal neuronal loss and axon reorganisation of the dentate gyrus in the mouse pilocarpine model of temporal lobe epilepsy

... epileptogenesis in temporal lobe epilepsy The aims of the present study in the mouse pilocarpine model of TLE included: 1) systemic investigation of the patterns of neuronal loss at different septotemporal ... Khanna, and Feng Ru Tang, (2009) Patterns of Hippocampal Neuronal Loss and Axon Reorganization of the Dentate Gyrus in the Mouse Pilocarpine Model of Temporal Lobe Epilepsy J Neurosci Res 87(5): ... intracellular calcium-binding proteins, containing EF-hand calcium binding motifs, and related to calmodulin and troponin-C The biological roles of Calbindin D28k include calcium regulation and calcium-dependent...

báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf

... Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues Nadia M Luheshi1, Krisztina J Kovács2, Gloria ... sub-cellular distribution of IL-1α in injured areas is not uniform suggesting that it is regulated Conclusions The early expression of IL-1α in areas of focal neuronal injury suggests that it is the ... inflammation is known as a major contributor to disease and injury [14], and IL-1α has become recognised as a major mediator of sterile tissue injury [15, 16] Thus the data presented here extend our, and...

MECHANICAL EQUIVALENT OF HEAT - Instruction Manual and Experiment Guide for the PASCO scientific Model TD-8551A potx

... is called the Mechanical Equivalent of Heat The PASCO scientific Model TD-8551A Mechanical Equivalent of Heat apparatus allows accurate determination of the Mechanical Equivalent of Heat (to within ... temperature of the cylinder; and Ti is the initial temperature of the cylinder, just before cranking Calculating J, the Mechanical Equivalent of Heat J is just the ratio of the work performed to the heat ... manual for more information on the life of Benjamin Thompson—Count Rumford, of Bavaria 01 2-0 4331E Mechanical Equivalent of Heat Operation Step by step instructions for using the Mechanical Equivalent...

báo cáo hóa học: " Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson''''s disease" pptx

... important role in the secondary activation of microglia, in the progression of the inflammatory response, and in the progressive loss of the dopaminergic neurons in MPTPinduced PD Therefore, COX-2 ... oxidative and inflammatory insults The positive feed back loop may continue until the additional neuronal death (~50% of the remaining of the initial death) combined with the initial loss exceed the ... benefit in this model We hypothesized that COX-2 inhibition or deficiency mediates effects involved in the neuroprotection of the SNpc dopaminergic neurons in MPTP- induced mouse parkinsonism...

Three essays on real estate, environmental, and urban economics using the hedonic price model technique

... graduated with a M.Sc in Economics in August 2004 iv DISSERTATION ABSTRACT THREE ESSAYS ON REAL ESTATE, ENVIRONMENTAL, AND URBAN ECONOMICS USING THE HEDONIC PRICE MODEL TECHNIQUE Andres Jauregui Doctor ... Stephen L McFarland Acting Dean Graduate School THREE ESSAYS ON REAL ESTATE, ENVIRONMENTAL, AND URBAN ECONOMICS USING THE HEDONIC PRICE MODEL TECHNIQUE Andres Jauregui Permission is granted to ... Arbor, MI 48106-1346 THREE ESSAYS ON REAL ESTATE, ENVIRONMENTAL, AND URBAN ECONOMICS USING THE HEDONIC PRICE MODEL TECHNIQUE Except where a reference is made to the work of others, the work described...

Báo cáo khoa học: "Erythropoietin improves skeletal muscle microcirculation and tissue bioenergetics in a mouse sepsis model" ppsx

... received general anaesthesia with ketamine/xylazine 80:10 mg/kg via intraperitoneal injection Sepsis was induced by cecal ligation and perforation (CLP) An incision was made along the linea alba The ... tissues in the cardiovascular system, including cardiomyocytes, vascular smooth muscle, and endothelial cells, and has been shown to mediate anti-apoptotic, anti-inflammatory, and endothelial cell ... important intellectual content and approved the final version of the manuscript PY, WH, and JR carried out the animal experiments and acquisition of data RK and AX contributed equally in drafting...

Báo cáo y học: "Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer''''s disease" pot

... pathophysiology linked to ion channel activity Seizure activity characteristic of epilepsy is the result of a dysregulation of inhibitory and excitatory neuronal signaling largely controlled by ion ... spinal motor neuron protein in spinal muscular atrophy [2], cardiac troponin T, insulin receptor, myotubularin-related 1, and other proteins in myotonic dystrophies [3-5], and the tau protein in ... alternative splicing and two common and important neurological conditions, with the aim of identifying alternative splicing patterns of potential relevance to human disease Mesial temporal lobe epilepsy...

Anti inflammatory effects of inhibitors of the NF kb pathway in the mouse asthma model

... 1.2.1 Introduction of the NF- κB pathway 30 1.2.2 Role of the NF- κB pathway in allergic inflammation 39 1.3 Inhibitors of NF- κB signaling cascades 40 1.3.1 The GSK-3β inhibitor 41 1.3.1.1 The GSK-3 ... andrographolide may exert its antiinflammatory effects by inhibiting the phosphorylation of IKKβ and suppressing the DNA-binding activity of p65 Taken together, these present findings implicate that appropriate ... examine the potential anti- inflammatory effects of a GSK-3β inhibitor, namely TDZD-8, and a herbal medicinal, namely andrographolide in a mouse asthma model and elucidate their mechanisms in the...

Báo cáo sinh học: "∆RR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis" docx

... contributes to the neuroprotective activity of the CM from ∆RR-infected EOC2 and E0C20 cells To examine the effect of IL-10 on the neuroprotective capacity of the CM from ∆RR-infected EOC2 and EOC20 ... Page of 14 (page number not for citation purposes) Genetic Vaccines and Therapy 2008, 6:1 http://www.gvt-journal.com/content/6/1/1 ∆RR vaccination protects from KA-induced seizures and neuronal loss ... loss Figure ∆RR vaccination protects from KA-induced seizures and neuronal loss (A) Sprague Dawley rats were given intranasal doses of ∆RR or ∆PK (5 × 106 pfu) or PBS, and given of KA (15 mg/kg)...

Tài liệu tiếng anh Điện tử công suất mạch MERS Loss and rating consideration of a wind energy conversion system with reactive compensation by magnetic energy recovery switch

... Relative supply rating 8.4 pu 10.4 pu Rating and loss considerations for large scale system The losses and ratings of a large scale electrical conversion system with MERS solution and with a 2-level ... followed by description of experiments on a 50 kW PM generator and theoretical large scale system loss and rating investigations Magnetic Energy Recovery Switch (MERS) Configuration and operation ... generator voltage and the maximum output power can be increased A configuration using a variable series compensation device called a magnetic energy recovery switch (MERS) and a diode bridge has...

Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx

... long-term increase in the lung cancer mortality could help explain the turning point observed in the cancer mortality rate and YLL in 2006 [32] In men, colorectal cancer is the only common cancer ... increase in mortality rates from cancer, with more individuals surviving at risk of cancer We also observed a decrease in the number of deaths caused by gastro-intestinal diseases, injuries and poisoning, ... cancers in men and from cardiovascular diseases in women Keywords Cancer, Cardiovascular diseases, Mortality, Trends, Portugal Background In 2004, cardiovascular diseases (CVD) were the leading...

Tài liệu Báo cáo khoa học: Molecular characterization, phylogenetic relationships, and developmental expression patterns of prion genes in zebraﬁsh (Danio rerio) doc

... of mammalian origin by the ﬁsh intestine Comparison of zebraﬁsh prp1, prp2, and prp3 developmental expression patterns The developmental expression patterns of prp1 and prp2 coding for long zebraﬁsh ... distributed within the CNS 509 Expression of prion genes in the developing zebraﬁsh and in speciﬁc areas outside the CNS of the developing zebraﬁsh The prp1 and prp2-expressing sites in the developing ﬁsh ... Analysis of the N-terminal repeat domain of zebraﬁsh PrP1 and PrP2 The N-terminal domain of zebraﬁsh PrP1 contained nine repeats (residues 53–332) including four highly conserved 37 amino acid-long...

Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deﬁciency and hypervitaminosis pot

... procedures A single band of about 53 kDa was detected in liver and lung indicating that the amount of p53 protein was signiﬁcantly increased in the liver and lung from vitamin A- deﬁcient rats that in controls ... provides a mechanism that cult parturition in the rat as a result of vitamin A deﬁciency Am J Anat 57, 303–349 may explain in part the regulation of control of proliferative Ó FEBS 2003 Vitamin A status ... analysis of c-jun, p53 and p21WAF1/CIF1 in liver and lung of control, chronic vitamin A- deﬁciency and hypervitaminosis rats Based on the results found in the differential display study and taking...

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Từ khóa: the show will also end automatically when you have reached the end of all your slides you will see a black screen and can click with the mouse or press page down or enter to return to powerpoint inserting deleting and clearing cells with the mouse patterns of international trade in developed and developing countries the growth and patterns of international trade patterns of uk trade with china and india concepts lies and patterns of nature files contexts and patterns of processing clinicians apos patterns of work and communication regional patterns of endemism and species richness the case of squamates in china a sense of loss and anxiety in vivo functions in neuronal cell migration and axon guidance § 742 3 loss and revocation of regflex designation how to compensate non pecuniary loss and the problem of the lower threshold patterns of continuity and change people and patterns of collaboration Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoại Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấp Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Biện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọ Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Trả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùng Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIX Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2 Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật chuong 1 tong quan quan tri rui ro Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘI HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP