Investigations on the cellular and neuroprotective functions of nogo AReticulon 4a

... by Nogo- A expression The same effects are also observed by Nogo- B expression On the other hand, while Nogo- C and RTN3 confer some degree of protection against serum deprivation, staurosporine and ... in the inhibition of neurite outgrowth 1.2 Molecular characterization of Nogo- A 1.2.1 Nogo: part of the Reticulon family Identification and characterization of...

Ngày tải lên: 11/09/2015, 10:06

... in the cytoplasm of the epithelial (Figure 8), mononuclear and reticular cells When using the probe on the sections of the uninfected animals or the BHV-5 specific probe on the sections of the ... species The observations are useful for the early diagnosis of classical swine fever, with special regard to the detection and identification of...

Ngày tải lên: 12/08/2014, 18:22

... was dispersed inside the pore of support material (a) 3.3 Catalytic activities of Pt/SBA-15 in the oxidation of D-glucose The results of the oxidation of D-glucose carried out on Pt/SBA-15 catalyst ... Conclusions Figure HPLC-RID image of the products of D-glucose oxidation on PS-1 catalyst On the other hand, the reaction on Pt/SBA15 cat...

Ngày tải lên: 05/03/2014, 11:21

... mutants of the yeast protein confirms this We have explored the context-dependent effects of proline on ubiquitin stability by introducing a number of substitutions at positions P37 and P38 The equilibrium ... region (residues 21–35) N terminal to the X37 and X38 mutation sites, and the sequence of the short helix (residues 38–40) and fourth strand of...

Ngày tải lên: 07/03/2014, 16:20

... stoichiometries of participation of water, cations and anions in specific and non-specific binding of lac repressor to DNA Possible thermodynamic origins of the ‘‘glutamate effect’’ on protein–DNA ... function optimally Effects of mutations The point mutations are not in the immediate vicinity of the active site situated at the bottom of the positively charge...

Ngày tải lên: 16/03/2014, 06:20

... The chaotrope-induced unfolding was almost fully reversible in both forms of the protein Removal of the perturbation makes the protein regain its native form The unfolding reactions of both forms ... as the major and the minor forms of the holoACP structure, on the basis of their percentage contributions (65% and 35%, respectively) to the...

Ngày tải lên: 16/03/2014, 10:20

... rather than on the position of the mutation in the polypeptide chain, as demonstrated by the biophysical assays Our studies have provided additional contributions to the understanding of the effects ... charge of Tm The two other mutations (A63V and K70T) are located at the N-terminal region, far from the troponin binding region and occur at the g positio...

Ngày tải lên: 16/03/2014, 18:20

... by changing the distribution of interface states and the electron occupation on them In some cases, even the concentration of the adsorbed gas ions can be measured from the change of potential ... rather than the temperature dependence of adsorptionrdesorption kinetics of NO x gas region width, and e is the permittivity of the semiconductor From the cha...

Ngày tải lên: 20/03/2014, 13:04

... direction of magnetic moment of A ions and magnetic moment of B1 and B2 ions Comparing MSt and MSe from Tab 2, we could determine the canting angle between magnetic moments of B1 and B2 ions in ... superparamagnetic properties of Ni -Zn ferrite for nano-bio fusion applications ware reported [13] In this paper we study magnetic and electric properties includi...

Ngày tải lên: 22/03/2014, 11:20

... a GGN4 analogue with both the C-terminal 14 residue truncation and the substitution of the aspartic acid at position 16 by tryptophan, showed antimicrobial activity comparable to that of native ... the GGN4 analogues, including the native GGN4, showed a strong negative band near 200 nm and a weak and broad band around 222 nm, indicating a predominantly rando...

Ngày tải lên: 31/03/2014, 09:20

... (Bui et aI., 2004) There were studies that only compare the effect of drying methods alone (Chan et aI., 2009); and also study on the optimization of extraction conditions on herbs (Chirinos ... 20 20 21 22 23 2.6 Effect of Extraction Methods on Antioxidant Activity of Herbs 2.6.1 Effect of Extraction Solvents 2.6.2 Effect of Extraction Time 2.6.3 Effect of...

Ngày tải lên: 05/05/2014, 08:39

... moneyness of options between the pre and post periods for disclosure (recognition) As Murphy’s [1999] findings suggest, some firms grant options based on the number and others grant options based on the ... disclosure- only financial reporting regime versus a recognition regime The purpose is to understand how recognition versus disclosure in financial...

Ngày tải lên: 03/06/2014, 01:05

... et al.: The differential mediating effects of pain and depression on the physical and mental dimension of quality of life in Hong Kong Chinese adults Health and Quality of Life Outcomes 2010 8:1 ... mediation is established if the association between depression and QoL is reduced to zero The Sobel test [24] determined whether pain...

Ngày tải lên: 18/06/2014, 19:20