A systems biology approach to elucidating the frequency decoding mechanism governing differential mammalian gonadotropin subunit gene expression

... GnRH and through its intracellular mechanisms, allow the frequency of GnRH to dictate the predominance in the expression of any subunit gene A number of both theoretical and experimental approaches ... consequences of calcium release into the cytoplasm and the activation of PKCs is the firing of the three major MAPK cascades, culminating in the activation of extrace...

Ngày tải lên: 11/09/2015, 09:11

... this article as: Henkel et al.: A systems biology approach to analyse leaf carbohydrate metabolism in Arabidopsis thaliana EURASIP Journal on Bioinformatics and Systems Biology 2011 2011:2 Abbreviations ... presented a kinetic modelling approach to simulate and analyse diurnal dynamics of carbohydrate metabolism in A thaliana Based on simulated fluxes...

Ngày tải lên: 21/06/2014, 03:20

... identification and simulation A mathematical model was developed, representing central carbohydrate metabolism in leaves of A thaliana The model was based on the following system of ordinary differential ... in A thaliana A D B E C F Fig Maximum activities of enzymes in central carbohydrate metabolism during cold exposure (A C) Vmax values of three invertase...

Ngày tải lên: 14/02/2014, 22:20

... Text Mining Text mining is an “area within data mining that focuses on data from textual sources” (Feldman, 2003; Ye, 2003) Text mining is a large subfield of data mining It is an area that has developed ... research data are compared to the leadership skills needed that industry communicates in trade journals This comparison is determined using a subjective and approximate reasoning...

Ngày tải lên: 01/06/2014, 13:57

... Acta Veterinaria Scandinavica 2009, 51:36 Background Files with information on animal disease have a variety of applications at both the herd and national level, including monitoring the incidence ... the aim was to reveal perceptions and reasoning behind generation of data and to describe the interaction and relations between the recording of metritis scores and...

Ngày tải lên: 25/10/2012, 10:45

... server translates the information returned by the Sentinels into CycL and adds it to the KB This approach is potentially vulnerable to an attack on the Sentinels themselves, or to spoofing of their ... 95/98/NT/2000/XP, Linux RedHat and Solaris The Attack Planner enables the user to state plan goals, launch the planner and view the attack plans generated For exampl...

Ngày tải lên: 05/03/2014, 23:20

... to validate the mechanism of induction of GAL genes by galactose In each of the models, cytoplasmic Gal3 p is activated by galactose Further, Gal4 p dimerizes and interacts with the DNA to form the ... expression of GAL genes in response to galactose The GAL genetic switch The GAL regulatory network is composed of three regulatory proteins:...

Ngày tải lên: 07/03/2014, 16:20

... in registers for being filled to gaps found in the rest of the input sentence These registers are too powerful since they enable ATN to recognize the full class of context-sensitive grammars In ... goes out to seek Laay in the cane field and he finds that it is about to walk away.’ The sentence in (17) are split into two SVCs: the series of V1 to V3 and the...

Ngày tải lên: 08/03/2014, 21:20

... DNA evidence thus reunites more evidence against the matching suspect Bayesian network for a database search setting: suspect and one other individual in the database The Bayesian network earlier ... may focus directly on the following sections: Bayesian network for the island problem, ’ Bayesian network for a database search setting: suspect and one o...

Ngày tải lên: 23/03/2014, 12:20

... instead of a simple pronoun, as in (6) The situation- type of the text at the end o f the utterance of the second clause includcs the speaker with die property of having told the guy at the door to ... deriving the final situation- type of the text (6) ! told the guy at the door to watch ouL but the idiot wouldn'! listen The utterance corresponding...

Ngày tải lên: 24/03/2014, 01:21

... Illustration of the path a classifier must trace in order to identify the location of the gap from Figure At the top level, it must choose to recurse into the SQ node, and at the second level, into the ... downward from there, eventually predicting the location of the gap At each node we encounter, the classifier chooses either to recurse into one of the ch...

Ngày tải lên: 24/03/2014, 03:20

... indicate that the accuracy of our approach is not sensitive to small changes to these values 705 points that are closer to the hyperplane are more uncertain than those that are farther away We ... capture the largest variance in the data Therefore, each of them can be thought of as revealing an important dimension of the data Our Approach While spectral clustering addresse...

Ngày tải lên: 30/03/2014, 23:20

... using the human reference translations and the output of the MT system at a given point in time Using the same set of features, we expect the accuracy of the classifiers to go down over time as the ... sampling the initial datasets Thanks also to John Platt for helpful discussion on parameter setting for the SVM tools, and to the members of the MSR NLP grou...

Ngày tải lên: 31/03/2014, 04:20

... SR, AS and HH contributed equally to the content of the article and gave their final approval All authors read and approved the final manuscript Competing interests The authors declare that they ... kg−1) A total amount of about 700 kg artificial sediment was prepared for the experiments in the annular flume and half of the sediment was spiked with the abovedes...

Ngày tải lên: 20/06/2014, 21:20