On interaction motif inference from biomolecular interactions riding the growth of the high throughput sequential and structural data

... ON INTERACTION MOTIF INFERENCE FROM BIOMOLECULAR INTERACTIONS: RIDING THE GROWTH OF THE HIGH THROUGHPUT SEQUENTIAL AND STRUCTURAL DATA HUGO WILLY B Comp (Hons.), NUS A THESIS SUBMITTED FOR THE ... mentioned, domain-domain interaction is not the whole picture of protein-protein interaction There is another class of interaction where one of th...

Ngày tải lên: 10/09/2015, 15:52

... arrays [22] (C) Secondary structure elements of the Fyn SH3-domain The five b strands, numbered consecutively, are separated by the interaction loops (bold) making primary contacts with the ligand ... dependent on an initial interaction between the first prolinerich region of PAG and the SH3-domain of the kinase Fyn Our earlier investigations have highlighted the...

Ngày tải lên: 24/03/2014, 00:21

... to form the UII system: the UII receptor and the peptides UII and urotensin- related peptide (URP) In humans, both peptides are biologically synthesized from their own respective 124 and 119 amino ... approach for the investigation of the neurophysiological role of the UII system While our understanding of the molecular constituents of the UII system in mam...

Ngày tải lên: 19/02/2014, 07:20

... of stable motif pairs derived from our starting motif pairs and those derived from 10 sets of equal size of random starting motif pairs 85 4.11 The percentage of stable and significant motif pairs ... methods for discovering binding motif pairs from different types of protein interaction data These are the discovery of binding motif pairs in the...

Ngày tải lên: 15/09/2015, 17:09

... neither motifs can 22 Protein A Motif Discovery Algorithms Figure The One-to-Many (OTM) approach to finding motif from interaction data Dotted arrow denotes interaction between two sequences Motifs ... directly for motifs Specifically, not many motif discovery algorithms (in fact, only one algorithm to the best of our knowledge) have been designed to mine motifs directly fr...

Ngày tải lên: 30/09/2015, 14:24

... section number given after each one ask for, 29 butt in,14 fill out, 14 have on, 25 make out, 29 open up, 26 carry out, 28 head into, 17 stand up, 28 drop in, 29 hurry up, 25 trade in, 24 drop ... cut down, 23 drop in, 29 get away, 23 get back at, 17 luck out, 29 make out, 29 come apart, 29 flip out, 29 get off, 18 make up, 23 crack down, 23 go about, 17 look out, 29 run a...

Ngày tải lên: 01/11/2013, 12:20

... of Reading Activities in Language Classes Like other language skills, Reading skill also involves a variety of reading activities In a study of teaching reading, Forseth et al (1996) have analyzed ... activities in language teaching In addition, the author briefly introduces reading skill with definition of reading, the importance, the principles for te...

Ngày tải lên: 18/12/2013, 10:03

... al.: Effect modification of air pollution on Urinary 8-Hydroxy-2’-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions Environmental ... 8-hydroxydeoxyguanosine and indoor air pollution among non-smoking office employees Environ Res 2007, 103:331-337 20 Chuang KJ, Chang CC, Su TC,...

Ngày tải lên: 17/02/2014, 22:20

... ensure the generation of the ketone The ability of ScPDC and ZmPDC to decarboxylate indolepyruvate was examined under the same conditions In the case of ZmPDC maximum enzyme concentration was 2.3 ... independent of the concentration of the auxiliary enzyme, confirming that the coupled assay monitors the true rate of EcIPDC catalysis Figs and and Table illustr...

Ngày tải lên: 08/03/2014, 02:20

... ii Abstract The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client Mobility: Findings from Contra Costa, California This ... looks at the relationships among land use; the mobility of disabled and elderly recipients of public home healthcare; the...

Ngày tải lên: 14/03/2014, 17:20

... CAGGAAACAGCTATGAC CGGAATTCTGAAGGTGGCCCGCC AGGTGACAG CGCGGATCCAATCTTGATGGGGC AGCCGGAGAGG AGGAYTCTCTGGATAGTGG CTCACCACAGACGATWTCC CGGTAAGCCCATAACGCCCA CAGGCCAGGATTTGCAGCC CATAAACAYGAGCCAGTTGCC GAGTGGATGCACAGTCGTTG ... GAGTGGATGCACAGTCGTTG GAAACGGAGGTAGTGACACAT GCCTGCTCGAATTCGGGATG CTCCTTCTTGCACAAAAAGTG CTGCTCGAATTCGGGATG GTCYGGGTAATTCCTATATA GTGATCGAATTTGGGAAGATGATCCA CCCTTGCATTTAAACCTCAGGTACAC...

Ngày tải lên: 17/03/2014, 03:20

... signal The intensity of this signal strongly varied from preparation to preparation A decrease in specific activity was always accompanied by an increase in signal intensity, suggesting that the ... characterization of the Fe-only nitrogenase isolated from R capsulatus, which included a detailed comparison with the Mo- containing nitrogenase from the same or...

Ngày tải lên: 18/03/2014, 01:20

... differentials in health remain The Data 3.1 The Avon Longitudinal Study of Parents and Children (ALSPAC) We use a very rich UK data set on a cohort of children born in one region of the UK in the early ... can use this data as a check on the financial hardship based low- income measures Information is available on both financial hardship and family income...

Ngày tải lên: 22/03/2014, 09:20

... domain constituting the Ca2+ binding motif is found in a large number of Ca2+-binding proteins, and is also known as the EF hand [16] Proteins containing the EF hand are divided into two classes ... of LH1 from Tch tepidum have been purified and the amino acid sequences determined [12] In addition, the dimeric feature and the highly symmetric ring assembly of...

Ngày tải lên: 30/03/2014, 02:20

... most sumoylation E3 ligases contain RING domains Thus, this region may be a common site for E2–E3 interactions (c) In the SUMO-1–ubc9–RanBP2–RanGAP1 (Ran GTPaseactivating protein 1) complex, the ... and mechanism An intriguing question is how the individual components of the sumoylation machinery interact during the Interactions between sumoylation proteins various ste...

Ngày tải lên: 30/03/2014, 04:20