Molecular and computational approaches to understanding keloid scarring

... our understanding of the wound healing process 1.2 Approach and methodology We have decided to adopt both top down as well as reductionist approaches to understanding the mechanisms underlying keloid ... possible factor underlying the growth and formation of keloids is their resistance to apoptosis Keloid fibroblasts was found to be more resistant to Fas mediated apoptosis (Chodon et al 2000) and the ... approach to understanding keloid scarring through the use of microarray technology Results from the microarray experiments were then analyzed computationally to provide further insights into the molecular...

Báo cáo y học: " Computational and statistical approaches to analyzing variants identified by exome sequencing" pdf

... the exome that were inferred to be identical by descent PIGV (encoding phosphatidylinositol glycan class V), a gene that is involved in the synthesis of glycosylphosphatidylinositol, was identified ... Comprehensive approach to analyzing rare genetic variants PLoS One 2010, 5:e13584 93 Li Y, Byrnes AE, Li M: To identify associations with rare variants, just WHaIT: Weighted haplotype and imputation-based ... would be expected to have fewer total variants) and ancestry (individuals of African ancestry have more variants per exome than individuals of European ancestry [3], for example) By contrast, about...

Tài liệu Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors doc

... that more than one binding site exists for competitive ligands on nAChRs, and probably a-Conotoxin docking modes on neuronal nAChRs a-Conotoxin binding sites Of the 11 neuronally active a-conotoxins, ... Changeux, J.P (2000) Nicotinic receptors at the amino acid level Annu Rev Pharmacol Toxicol 40, 431–458 Karlin, A (2002) Emerging structure of the nicotinic acetylcholine receptors Nat Rev Neurosci ... Tsetlin, V.I (1999) Aromatic substitutions in a-conotoxin ImI Synthesis of iodinated photoactivatable derivative Toxicon 37, 1683–1695 Rogers, J.P., Luginbuhl, P., Pemberton, K., Harty, P., Wemmer,...

Đề tài " Classical and modular approaches to exponential Diophantine equations I. Fibonacci and Lucas perfect powers " pdf

... Mathematics, 163 (2006), 969–1018 Classical and modular approaches to exponential Diophantine equations I Fibonacci and Lucas perfect powers By Yann Bugeaud, Maurice Mignotte, and Samir Siksek* Abstract ... combination of classical techniques with the modular approach to show that the only perfect powers in the Fibonacci sequence are 0, 1, and 144 and the only perfect powers in the Lucas sequence are and Introduction ... problem A sequel combining the classical and modular approaches for Diophantine equations of the form x2 + D = y p has just been completed [13] CLASSICAL AND MODULAR APPROACHES 971 We delay presenting...

Báo cáo khoa học: "Evaluating and Combining Approaches to Selectional Preference Acquisition" pptx

... of the factors grammatical relation (Re!), verb (Verb), and probability band (Band) The factors Re! and Band had three levels each, and the factor Verb had 10 levels This yielded a total of Re! ... deriving selectional preferences over words, senses, or even classes, whereas Ciaramita and Johnson (2000) use Bayesian Belief Networks to quantify selectional preferences Although there is no standard ... primarily focused on verbs and their direct objects, ignoring the selectional preferences pertaining to subjects and prepositional complements The induction of selectional preferences typically addresses...

Báo cáo khoa học: "Computational Approaches to Sentence Completion" docx

... 2009) Sentence Completion via Language Modeling Perhaps the most straightforward approach to solving the sentence completion task is to form the complete sentence with each option in turn, and to ... activations s(t) is maintained and updated at each sentence position t These activations encapsulate the sentence history up to the tth word in a realvalued vector which typically has several hundred dimensions ... xx·yy 4.1 Total Word Similarity Perhaps the simplest way of doing sentence completion with LSA is to compute the total similarity of a potential answer a with the rest of the words in the sentence...

a comparison of dividend cash flow and earnings approaches to equity valuation

... cash flows were less than that of GAAP earnings As free cash flows are returns to debt, preferred and common equity (whereas earnings are "available to common") it appears that GAAP earnings are ... An exception is Kaplan and Ruback (1995) This contrasts with Kaplan and Ruback (1995) and Abarbanell and Bernard (1995) where prices are compared to values calculated from forecasts of cash flows ... alternative techniques under those conditions is examined A COMPARISON OF DIVIDEND, CASH FLOW, AND EARNINGS APPROACHES TO EQUITY VALUATION The calculation of equity value is typically characterized...

báo cáo hóa học:" Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors: A review of 57 cases" pptx

... preoperative Karnofsky and modified Tokuhashi scores with the type of the surgical approach in 57 patients with spinal metastases treated surgically and to evaluate the value of these scores in aiding ... surgical treatment of Table 3: Comparison of surgical approaches and mean survival time among Karnofsky's groups Karnofsky score Surgical approach Mean survival (months) Combined Anterolateral ... metastases of thoracic and lumbar spine Spine 1997, 22:239-45 North RB, LaRocca VR, Schwartz J, North CA, Zahurak M, Davis RF, McAfee PC: Surgical management of spinal metastases: analysis of prognostic...

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