Molecular and computational approaches to understanding keloid scarring

... our understanding of the wound healing process 1.2 Approach and methodology We have decided to adopt both top down as well as reductionist approaches to understanding the mechanisms underlying keloid ... possible factor underlying the growth and formation of keloids is their resistance to apoptosis Keloid fibroblasts was found to be more resistant to Fas mediated apopt...

Ngày tải lên: 10/09/2015, 15:48

... the exome that were inferred to be identical by descent PIGV (encoding phosphatidylinositol glycan class V), a gene that is involved in the synthesis of glycosylphosphatidylinositol, was identified ... Comprehensive approach to analyzing rare genetic variants PLoS One 2010, 5:e13584 93 Li Y, Byrnes AE, Li M: To identify associations with rare variants, just WHaIT: Weighted h...

Ngày tải lên: 09/08/2014, 23:20

... that more than one binding site exists for competitive ligands on nAChRs, and probably a-Conotoxin docking modes on neuronal nAChRs a-Conotoxin binding sites Of the 11 neuronally active a-conotoxins, ... Changeux, J.P (2000) Nicotinic receptors at the amino acid level Annu Rev Pharmacol Toxicol 40, 431–458 Karlin, A (2002) Emerging structure of the nicotinic acetylcholine recep...

Ngày tải lên: 19/02/2014, 12:20

... Mathematics, 163 (2006), 969–1018 Classical and modular approaches to exponential Diophantine equations I Fibonacci and Lucas perfect powers By Yann Bugeaud, Maurice Mignotte, and Samir Siksek* Abstract ... combination of classical techniques with the modular approach to show that the only perfect powers in the Fibonacci sequence are 0, 1, and 144 an...

Ngày tải lên: 06/03/2014, 08:21

... of the factors grammatical relation (Re!), verb (Verb), and probability band (Band) The factors Re! and Band had three levels each, and the factor Verb had 10 levels This yielded a total of Re! ... deriving selectional preferences over words, senses, or even classes, whereas Ciaramita and Johnson (2000) use Bayesian Belief Networks to quantify selectional preferences Although th...

Ngày tải lên: 08/03/2014, 21:20

... 2009) Sentence Completion via Language Modeling Perhaps the most straightforward approach to solving the sentence completion task is to form the complete sentence with each option in turn, and to ... activations s(t) is maintained and updated at each sentence position t These activations encapsulate the sentence history up to the tth word in a realvalued vector which typical...

Ngày tải lên: 16/03/2014, 19:20

... cash flows were less than that of GAAP earnings As free cash flows are returns to debt, preferred and common equity (whereas earnings are "available to common") it appears that GAAP earnings are ... An exception is Kaplan and Ruback (1995) This contrasts with Kaplan and Ruback (1995) and Abarbanell and Bernard (1995) where prices are compared to values calculated...

Ngày tải lên: 23/04/2014, 16:06

... preoperative Karnofsky and modified Tokuhashi scores with the type of the surgical approach in 57 patients with spinal metastases treated surgically and to evaluate the value of these scores in aiding ... surgical treatment of Table 3: Comparison of surgical approaches and mean survival time among Karnofsky's groups Karnofsky score Surgical approach Mean su...

Ngày tải lên: 20/06/2014, 01:20