Near infrared autofluorescence imaging and spectroscopy for early detection of precancer and cancer in the colon

... fluorescence imaging and spectroscopy for detection of precancer and cancer in the colon 1.3 Challenges for Colonoscopy Screening To date, colonoscopy is the accepted gold standard for the screening and ... endoscopy for improving the non-invasive in vivo detection and diagnosis of colon cancer As introduced in the previous section, combining different technologies and integrating them into a multifunctional ... accuracy of 95.8% among the NIR AF and NIR DR imaging modalities, affirming the potential of the integrated NIR AF/DR imaging with polarization for improving the early detection and diagnosis of malignant...

Near infrared raman spectroscopy for early detection of cervical precancer

... NEAR- INFRARED RAMAN SPECTROSCOPY FOR EARLY DETECTION OF CERVICAL PRECANCER MO JIANHUA A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY OF ENGINEERING DIVISION OF BIOENGINEERING ... potential of NIR Raman spectroscopy in both fingerprint and high wavenumber (HW) regions for the ex vivo and in vivo detection of cervical precancer To further enhance the acquisition of Raman signal ... infrared spectroscopy) for the detection of cervical precancer and cancer Finally, we will present the motivations, objectives and organization of this thesis 1.2 Raman Spectroscopy 1.2.1 The Raman...

Báo cáo khoa học: "Near infrared analysis as a tool for rapid screening of some major wood characteristics in a eucalyptus breeding program" ppsx

... screening A value of above 3.0 is regarded as satisfactory for screening (for example in plant breeding) , values of and upward are suitable for quality control analysis, and values of above are ... composition of lignin, shrinkage or the extent of longitudinal growth stress This paper evaluates the potential of NIRS for the assessment of some major chemical, physical and mechanical wood characteristics ... structures in lignins by cleavage of arylglycerol-β-aryl ether bonds As a single method, thioacidolyse has a definite advantage in that it may be used to characterize unambiguously typical and prominent...

Serum Biomarkers for Early Detection of Gynecologic Cancers ppt

... Sensitivity early 83% early, M early, all 95% 89% early, S early, E 94% 98% Specificity early 94% early, M early, all 92% 97% early, S early, E 94% 98% 95% 99% The sensitivity and specificity of each serum ... with values for CA 125, ApoA-I, TF, and TTR for the early detection of ovarian cancer [83] This model provided a sensitivity of 89% and a specificity of 97% for the detection of early stage ovarian ... endometrial, and cervical cancers, it is critical to detect the disease at the earliest possible stage The discovery of useful serum biomarkers for the early detection of gynecologic cancers has thus...

Báo cáo y học: " Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation" ppsx

... be investigated Recombination between the human tropic PERV -A and the ecotropic PERV-C has been described in normal pigs and in melanoma-bearing animals, and recombinant PERV -A/ C was characterized ... tissues and organs to humans Xenotransplantation is a potential solution for the shortage of allogeneic human organs Designated pathogen-free breeding and maintenance of pigs can prevent the transmission ... three of the patients showed a clear antibody response against the p27Gag of PERV in a Western blot assay, and a small percentage of blood donors (5%) have also been found to react with the p27Gag...

Báo cáo sinh học: "Evidence for large domains of similarly expressed genes in the Drosophila genome" docx

... divided into domains important for controlling the expression of groups of adjacent genes First, there is evidence from budding yeast that some genes are found in pairs or triplets of adjacent genes ... 500 The ‘Expected’ column gives an approximate number the window size increases from two to eight genes, the net number of genes in groups (that is, the genes in groups in the ordered dataset minus ... about ten genes, so we used a window size of ten for the remainder of our analysis There are no qualitative differences in the nature of groups identified by larger window sizes Many of the ten-gene...

Báo cáo y học: "Early Detection of cytokine protein expression in mouse lung homogenates using suspension bead array" ppt

... significantly increased IL-6 and GM-CSF proteins and decreased IL-2 protein expression in lung tissue homogenates using suspension bead array These findings correlated with cytokine protein expression ... analysis of cytokine protein expression in plasma of lipopolysaccharidetreated mice Cytokine 2005, 32:194-198 Matalka KZ, Tutunji MF, Abu-Baker M, Abu Baker Y: Measurement of protein cytokines in ... Journal of Inflammation 2006, 3:15 inflammatory cytokines, interleukin-6 (IL-6) and macrophage inflammatory protein- 2 (MIP-2) protein levels in mouse lung tissue homogenates are increased following...

Báo cáo y học: " New horizons: NT-proBNP for risk stratification of patients with shock in the intensive care unit" pps

... output in patients with various types of shock in the ICU [1,14] In agreement with the findings reported by Jannuzzi and coworkers in the present issue of Critical Care [1], previous investigators ... low NT-proBNP concentrations may be useful indicators to avoid PAC in low risk patients in the ICU Several mechanisms account for increased natriuretic peptide levels in shock patients and for the ... regimens according to PAC information across the spectrum of critically ill patients Further clinical trials should lead to the establishment of treatment protocols for the use of PAC in this patient...

Báo cáo y học: " Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infectio." pot

... diversity in both the Nef- and RT-coding regions in the colon We explained this increased viral diversity by the higher levels of HIV- 1 replication that we and others have observed in the colon ... were involved in writing the paper KN and KC were involved in designing the methods for collecting, analyzing and interpreting data, and helped putting the data and parts of the manuscript together ... Probably in part due to the activated state of the GI tract in HIV- 1 infection, lymphoid cells obtained from the GI-tract are very susceptible to HIV infection compared to blood or other tissue lymphocytes...

Báo cáo y học: "Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study" ppt

... Arthritis Research & Therapy Vol No Saadat et al Table Table Proteoglycan content in cartilage of cyclically loaded rabbit metacarpophalangeal joints and their contra-lateral controls Collagen ... out the FTIR data acquisition and analysis, performed the statistical analyses, and drafted the manuscript HL carried out the PLM data acquisition and analysis and helped draft the manuscript SM ... outcome measures were mean integrated value of proteoglycan in the superficial zone of cartilage, mean integrated value of proteoglycan in the mid zone of cartilage, and mean integrated value of proteoglycan...

Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps

... hospital's database This database contains all physician's reports, patient baseline data, routine laboratory results, pharmacology data, costs per R446 patient and day of specific medications ... plasma measurements of IL-8 and G-CSF and tracheal aspirate levels of G-CSF, employing a new laboratory method that allows simultaneous determination of parameters from 50 µl blood or tracheal ... that routine surveillance by determination of cytokine levels in plasma and tracheal aspirates will allow safe discontinuation of antibiotic therapy within 24 hours if the proposed laboratory prediction...

Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications

... SURFACE FUNCTIONALIZATION OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR POTENTIAL CELL TARGETING, IMAGING, AND CANCER THERAPY APPLICATIONS HUANG CHAO (B.ENG., ... Objectives and Scopes The overall aim of this thesis is to develop various functional polymers as surface coatings of SPIONs for potential cell targeting, MRI, and cancer therapy applications ... nanomaterials, magnetic iron oxide nanoparticles are of intense current interest and have been successfully used for clinical applications, for example, molecular imaging Magnetic iron oxide nanoparticles...

Light sheet based fluorescence correlation and cross correlation spectroscopy for quantitative measurements of bio molecules in live cells

... LIGHT SHEET BASED FLUORESCENCE CORRELATION AND CROSS -CORRELATION SPECTROSCOPY FOR QUANTITATIVE MEASUREMENTS OF BIO- MOLECULES IN LIVE CELLS ANAND PRATAP SINGH (M.Sc Chemistry, BHU, INDIA) ... enzyme-kinetics and ligand-receptor stoichiometry [121, 122] and in vivo protein-protein interaction in live cells and even in live organisms [33, 123127] 2.5 Principles and Theoretical Aspects of ... microscopy) and camera based FCS and FCCS (uorescence cross -correlation spectroscopy) , which creates spatio-temporal diffusion and concentration maps of bio- molecules in vitro and in live cells Imaging...

Tài liệu PROTEOMIC APPLICATIONS FOR THE EARLY DETECTION OF CANCER doc

... the early detection of cancer before these goals come to fruition These issues underscore the need for higher throughput and high-sensitivity tests for the early detection of cancer High-throughput ... rich source of biomarkers for the early detection of cancer The blood proteome changes constantly as a consequence of the perfusion of the diseased organ adding, subtracting or modifying the circulating ... distribution with early detection Figure | The potential impact of proteomic pattern diagnostics for the early detection of ovarian cancer on 5-year survival statistics Today, most ovarian cancer cases...

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