Lung cancer in never smokers

... x Lung cancer: An introduction Lung cancer in never- smokers: Evidence for a distinct clinical entity from smoking –related lung cancer 10 Lung Cancer in Singapore 15 The Gene and Environment in ... CHAPTER LUNG CANCER IN SINGAPORE I) Incidence Introduction Lung cancer was the cancer with the highest incidence in men and the third highest incidence in wo...

Ngày tải lên: 09/09/2015, 18:51

... Flenaugh EL Lung Cancer Disparities in African Americans: Health versus Health Care Clinics in Chest Medicine 2006 27: 431-439 19 Too Many Cases, Too Many Deaths: Lung Cancer in African Americans ... happen In the back of your mind, you think maybe they’ll find a cure Statistics don’t show those miracles.” Too Many Cases, Too Many Deaths: Lung...

Ngày tải lên: 15/03/2014, 01:20

... Cite this article as: Surati et al.: Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database Journal of Clinical Bioinformatics 2011 ... staining of one core of a TMA to that of a control core on the same slide A score of indicates faint staining, indicates medium intensity staining, and indic...

Ngày tải lên: 10/08/2014, 09:22

... Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers Arthritis Research & Therapy 2011 13:R65 ... Salway F, Symmons D, Lunt M, Worthington J, Silman A: Polymorphisms in the mannose binding lectin (MBL) gene are not associated with radio...

Ngày tải lên: 12/08/2014, 15:23

... the question of how closely tumors induced by JSRV Env in mice resemble those induced by JSRV in sheep, in part to determine if the oncogenic activity of Env can entirely account for the disease ... tumors induced by administration of an AAV6 vector that expresses only the ENTV Env protein [12] Mab staining of tumors from sheep We next tested the M...

Ngày tải lên: 13/08/2014, 09:20

... non -cancer controls by Methylation densitylung disease Methylation density of DAPK promoter in non -cancer controls by underlying lung disease The methylation density of DAPK promoter in EBC samples ... of DAPK promoter by tumor histology in Methylation density of DAPK promoter by tumor histology in lung cancer cases The methylation density of DAPK promoter...

Ngày tải lên: 12/08/2014, 14:20

... Both RPA and XPA preferentially bind damaged DNA, and because RPA and XPA directly interact in the absence of DNA, the RPA-XPA complex has been implicated as a key component in the earliest stage ... implicates the damaged DNA binding protein heterodimer in damage recognition, because the complex binds damaged DNA with high affinity [43] and can dramatically increase...

Ngày tải lên: 31/10/2012, 14:59

... concentrations of elemental carbon reported in some urban areas may confer increased risk of lung cancer Thus, if the diesel exhaust/ lung cancer relation is causal, the public health burden of the carcinogenicity ... of the National Institute for Occupational Safety and Health and Mustafa Dosemeci, formerly of the National Cancer Institute, for their wo...

Ngày tải lên: 22/03/2014, 17:20

... further analysis Binding of endogenous Sp1 from lung cancer cell lines to the p73 P1 promoter In order to validate the ability of endogenous Sp1 to bind to the p73 P1 promoter within the cellular ... TAp73c in lung cancer via highly conserved Sp1- binding sites on the p73 P1 promoter In addition, TAp73c and Sp1 are co-overexpressed...

Ngày tải lên: 29/03/2014, 09:20

... GM1 and caveolin-1 distribution within membrane fractions In order to determine the effect of MbCD on the integrity of rafts and the localization of MRP1, GM1 and caveolin-1, GLC4 ⁄ ADR cells ... MRP1 in the absence (B) and in the presence (C) of treatment with MbCD S and R stand for GLC4 (sensitive) and GLC4 ⁄ ADR (resistant) cells 6–9 The amount of...

Ngày tải lên: 30/03/2014, 09:20

... participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing of the manuscript ... suppressor genes could be methylated in lung cell lines and tumors Next, we determined whether the methylation status of such genes could contribute for lung...

Ngày tải lên: 18/06/2014, 16:20

... [14]: = negative or faint staining in 10% of cancer cells; = moderate staining; = strong staining A score of was considered negative, a score of was considered ... Discussion EGFR is a member of the ErbB family of receptor tyrosine kinases, which also includes HER2/neu, HER3, and HER4 [15] Activating mutations in the tyrosine kinase domain, involving mainly exons ... Gazdar...

Ngày tải lên: 18/06/2014, 16:20

... al.: Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins Journal of Translational Medicine 2011 9:2 Submit your next ... to tumor induced by E6/E7 oncoproteins and human SCLC In particular, the Aryl Hydrocarbon receptor signaling is the predominant pathway dere...

Ngày tải lên: 18/06/2014, 16:20

... results Potential microRNA-based therapy is now being exploited in cancer, attempting to modulate their expression, reintroducing microRNAs lost in cancer, or inhibiting oncogenic microRNAs by using ... this article as: Donnem et al.: Prognostic Impact of MiR-155 in NonSmall Cell Lung Cancer Evaluated by in Situ Hybridization Journal of Translational Medicine 2...

Ngày tải lên: 18/06/2014, 16:20

... phosphorylating the retinoblastoma protein Overexpression of CDK4 has been described in many tumors, including lung cancer In this investigation, we analyzed the expression of CDK4 protein in lung cancer ... staining intensity and the percentage of positive staining areas of cells The staining intensity was scored as previously described(0-3) [8,9] and the percentage...

Ngày tải lên: 18/06/2014, 19:20