Host viral interactions host factors in coronavirus replication and coronaviral strategies of immune evasion

... cofactors that have roles in modulating coronavirus replication In the second part of the thesis, we focused on understanding the interplay between coronavirus infection and host cell innate immune ... regulatory domains such as the 5’- and 3’ UTR, and TRS of leader (TRS-L) and each ORF (TRS-B), and this is mediated by protein-RNA and protein-protein interaction...

Ngày tải lên: 09/09/2015, 10:07

... Apoptosis resistance is independent of the magnitude of viral replication Apoptosis resistance is independent of the magnitude of viral replication A) Jurkat and J1.1 cells were incubated in the ... independent of the magnitude of viral replication Apoptosis resistance of HIV persistenly-infected cell lines involves modulation of...

Ngày tải lên: 13/08/2014, 06:20

... two inhibitors of the IFN-induced protein kinase R (PKR), inhibit RNAi pathways in plants and in Drosophila cells [12] HIV- 1 Tat protein acts as an RNAi suppressor in the pathway mediated by shRNAs ... shRNAs but not siRNAs, suggesting a specificity of action [10] Adenovirus VA RNAI and VA RNAII are cleaved by Dicer and act as RNAi suppressors [13] Both Tat protein and...

Ngày tải lên: 13/08/2014, 09:21

... rate during the warm season for the first lactation and during the cold season for the second lactation Cow parity and calving season were eliminated from the final model since they did not influence ... service and/ or conception were not related to the occurrence of retained placenta [6,35,47] The effect of retained placenta was much greater on the...

Ngày tải lên: 07/08/2014, 18:21

... radiation-induced and bleomycin-induced lung injury, reduces alveolar damage by hydrochloric acid instillation, and decreases hyperoxia-induced mortality [24,25] Such beneficial effects are likely to ... development and disease follows Growth factors in development Growth factors are involved in virtually all aspects of lung development During the initial stages of lu...

Ngày tải lên: 12/08/2014, 18:20

Ngày tải lên: 15/02/2014, 17:20

... serine and glycine was reduced from 33% in the light to 25% in the dark (Fig 7A) Glutamine and asparagine were the major amino acids in the xylem sap in both the light (63% of the total amino acids) ... 3195 Amino acid metabolism and translocation M.-H Valadier et al Table Amino acid composition in leaves, and amino acid percentage ratio i...

Ngày tải lên: 18/02/2014, 18:20

... that the hypodermis of the body wall, which synthesizes components of the cuticle, may offer a useful target for studies into the mechanism of the development and molting process in the roundworms ... presence of increasing concentrations of inhibitors for 10 days, and the number of molting larvae was determined Molting was manifested by shedding of...

Ngày tải lên: 20/02/2014, 11:20

... in Role of helix and C-termini in bradykinin receptors receptor signaling because: (a) interruption of the amphipathic structure of B1wt helix in B1wt and B1KB2 through the presence of a serine ... TSIfiAAA N3 38* B1wt B1RB2 B1NB2 B1CB2 B1KB2 B1KB2 ⁄ SfiV B1KB2 ⁄ QGVfiKQ B1KB2 ⁄ VCfiCV B1YB2 B1V323S 10400 5020 52 98 383 2 625 127 511 1701 182 3 17 58 2142 1 786...

Ngày tải lên: 07/03/2014, 16:20

... : L-chain fhx/P25 A role of L-chain in the protection of a1 ,2-mannose residues of the N-linked oligosaccharide chains of fhx/P25 in the elementary unit The PSG cell extract of Nd-sD mutant was ... level of normal L-chain It implies that numbers of the normal elementary unit are assembled in proportion to the available numbers of...

Ngày tải lên: 16/03/2014, 16:20

... analyzed Finally, section contains a summary and conclusion 2 The impact of fodder trees on milk production and income among smallholder dairy farmers in East Africa and the role of research Conceptual ... 24 The impact of fodder trees on milk production and income among smallholder dairy farmers in East Africa...

Ngày tải lên: 24/03/2014, 04:20

... raised in somewhere northward from the north of North Viet Nam.   In Devonian,  the north of North Viet Nam was  the southern  margin  of a  continent,  where  alluvial  and continental  deposits took place.  In ... development  of Viet Nam and Southeast  Asian  in common.  In the tectonic  differentiation of the Bac Bo region in Mesozoic,   other unconformities probably...

Ngày tải lên: 28/03/2014, 15:20

... protein–protein interactions [6], as well as in the structural stability of proteins [23–25] Inspection of a preliminary structural model of cyt c6, based on the known structure of cytochrome c6 from ... oxygen of D72 Taking the functionally and structurally interesting mutant D72K as a material starting point, we aimed to study the contribution of the...

Ngày tải lên: 30/03/2014, 20:20

Ngày tải lên: 24/04/2014, 17:18

Ngày tải lên: 12/06/2014, 11:36