GENOME WIDE ASSOCIATION STUDIES OF CORONARY ARTERY DISEASE IN SINGAPOREAN CHINESE POPULATIONS

... Singapore Coronary Artery Genetics Study xv SCES: Singapore Chinese Eye Study SCES: Singapore Chinese Eye Study SCHS: Singapore Chinese Health Study SiMES: Singapore Malay Eye Study SINDI: Singapore ... that studies of coronary artery disease in Asia are conducted to address this increasing burden 1.3 Overview of the etiology of coronary artery disease The etio...

Ngày tải lên: 09/09/2015, 08:17

... monozygous twins, full siblings, and parent-offspring In each instance, the sample with the higher call-rate was retained in the analysis Analysis of association statistics After sample and SNP quality ... Working Group, Medical Faculty, University of Indonesia, Jakarta, Indonesia 8Samara Oblast Tuberculosis Dispensary, Samara City, Samara, Russian Federation 9Clinical TB and HIV...

Ngày tải lên: 06/03/2014, 04:20

... susceptibility to melanoma may also result in high-risk predisposition to other such forms of cutaneous malignancies [12] Risk variants of cutaneous malignancies Association with pigmentation phenotype and ... 1)) for CM and BCC risk Three cohorts (810 individuals with CM and 36,723 non-CM controls from Iceland; 1,033 CM cases and 2,650 controls from Sweden and...

Ngày tải lên: 11/08/2014, 12:20

... as: Sugino H, et al.: DNA microarray analysis of rheumatoid arthritis susceptibility genes identified by genome-wide association studies Arthritis Research & Therapy 2010, 12:401 ... financially supported partly by the grant from the Ministry of Health, Labor and Welfare of Japan Author details Graduate School of Frontier Bioscience, Osaka University, 1-3 Yam...

Ngày tải lên: 12/08/2014, 11:23

... consisting of Telugas and Tamils from southeastern India and a minority of Sikhs and Pathans from north India and accounts for 7.9% of the Singapore population The immigrant Chinese and Indians ... ethnic Chinese were not different from that in the ethnic Indians, in spite of a much lower CAD incidence in the ethnic Chinese (57) Because of Singapore's multira...

Ngày tải lên: 30/09/2015, 14:23

... results of these initial trials indicate that the ZES is safe and reduces the rates of clinical and angiographic restenosis in patients with symptomatic coronary artery disease (CAD; 4) Also the safety ... Abbreviations ACC: American College of Cardiology; AHA: American Heart Association; CABG: coronary artery binding graft; CK: creatine kinase; MACE: major adverse...

Ngày tải lên: 25/10/2012, 11:18

... KW, et al .: Color Doppler myocardial imaging: a new technique for the assessment of myocardial function J Am Soc Echocardiogr 1994, 7:4 41–458 Tissue Doppler imaging and coronary artery disease ... different there is deformation of the tissue in between In the case that the two locations are getting closer there is myocardial shortening, and when they move...

Ngày tải lên: 29/06/2014, 11:20

... the key pathways involved in lupus pathogenesis, with each pathway constructed of a number of interacting proteins making an individual contribution to disease susceptibility Page of (page number ... Arthritis Research & Therapy Vol 11 No Cunninghame Graham reproducibility between GWAS may reflect an overall lack of power for each individual study, since each published GWAS was of inter...

Ngày tải lên: 09/08/2014, 14:22

... consistency of results across studies and to identify regions that contain asthma and atopy susceptibility genes The aim of the current study was to complete the first meta-analysis of available ... analysis combines data from 10 years of asthma and atopy genetics and is extremely timely providing a definitive analysis of available linkage data to complement the high...

Ngày tải lên: 12/08/2014, 15:21

... Importance of cumulative exposure to elevated cholesterol and blood pressure in development of atherosclerotic coronary artery disease in systemic lupus erythematosus: a prospective proof -of- concept ... erythematosus, atherosclerosis, coronary artery disease, risk factors Introduction Systemic lupus erythematosus (SLE) is associated wit...

Ngày tải lên: 12/08/2014, 18:20

... feature selection methods confined to genome- wide association studies in Subsection Chapter1: Introduction 1.3.1 Model selection methods and some feature selection methods incorporated into model selection ... original SCAD method Chapter 3: Model selection criterion in generalized linear models 37 Chapter Model Selection Criteria in Generalized Linea...

Ngày tải lên: 11/09/2015, 16:05

... Summary viii List of Publications x List of Abbreviations xi List of Tables xiv List of Figures xv Introduction to Coronary Artery Disease 1.1 Definition of coronary artery disease ... Cumulative age distribution of mt5178C and mt5178A subjects 65 xv Chapter Introduction to Coronary Artery Disease 1.1 Definition of coronary artery disease Ischemic heart...

Ngày tải lên: 07/10/2015, 10:02

... et al Glucosinolate biosynthesis genes in Brassica rapa Fig Biosynthesis pathways of the three major groups of glucosinolates in B rapa The genes involved in each step are shown Numbers in parenthesis ... expression of Arabidopsis glucosinolate synthesis genes altered the glucosinolate profile in Chinese cabbage [50,51] Because most of the Arabidopsis gen...

Ngày tải lên: 29/03/2014, 23:20

... intake of fat and protein and a lower intake of carbohydrate) The association between the low-carbohydrate-diet score and the risk of coronary heart disease was examined Results During 20 years of ... fat and protein intake and the highest carbohydrate intake) to 30 (the highest protein and fat intake and the lowest carbohydrate intake) Therefore,...

Ngày tải lên: 27/06/2014, 00:20