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CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF TRACE AMOUNT OF SEX HORMONE RECEPTOR ACTIVE COMPOUNDS IN PROSTATE CANCER RELATED BIOLOGICAL SAMPLES

CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF TRACE AMOUNT OF SEX HORMONE RECEPTOR ACTIVE COMPOUNDS IN PROSTATE CANCER RELATED BIOLOGICAL SAMPLES

CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF TRACE AMOUNT OF SEX HORMONE RECEPTOR ACTIVE COMPOUNDS IN PROSTATE CANCER RELATED BIOLOGICAL SAMPLES

... Validation of A4 in g/L of PBS/BSA Table 5a Interday Validation of T in g/L of PBS/BSA Table 5b Intraday Validation of T in g/L of PBS/BSA Table 6a Interday Validation of DHT in g/L of PBS/BSA ... 4.3.2 Determination of Saturating Doses of Known AKR1C3 Inhibitor and Dimethoxycurcumin and its Potential as AKR1C3 Enzyme Inhibitor 126 4.3.3 Investigation of Dimethoxycurcumin using LC-MS/MS ... Mechanisms Behind Development of Castration Resistant Prostate Cancer Table Analysis of LC-MS/MS Pros and Cons in Clinical Diagnostics Table 4a Interday Validation of A4 in g/L of PBS/BSA Table 4b Intraday...
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Báo cáo khoa học: Characterization of a Cry1Ac-receptor alkaline phosphatase in susceptible and resistant Heliothis virescens larvae potx

Báo cáo khoa học: Characterization of a Cry1Ac-receptor alkaline phosphatase in susceptible and resistant Heliothis virescens larvae potx

... kept at °C and used within 10 days Quantification of alkaline phosphatase and aminopeptidase activities Specific alkaline phosphatase (ALP) and N-aminopeptidase (APN) enzymatic activities of BBMV ... sugar Canavalis ensiformis (ConA) a- Man a- Glc Galb1 fi 3GalNAc Galb1 fi 3,4GlcNAc a/ bGalNAc a/ bGal Galb1 fi 4GlcNAc Gala1 fi 3Gal GalNAca1 fi 3GalNAc GalNAca1 fi 3Gal Galb1 fi 3GalNAc Galb1 fi 3,4GlcNAc ... amounts in BBMV from YHD2 larvae would result in reduced alkaline phosphatase activity Alkaline phosphatase activity in blots of BBMV proteins from YDK and F1 larvae was similar, and higher than activity...
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báo cáo hóa học:

báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx

... expression of β-actin mRNA and AMACR mRNA in prostate cancer line LNCaP, but only very weak expression of AMACR mRNA was observed in normal adult liver and pancreas (Figure 1A) In contrast, the AMACR ... immunohistochemical staining In contrast, PSA was stained in both prostate cancer tissue and non-cancerous tissue (Figure 2C) These data indicated that AMACR had a mostly cancer- specific expression profile at ... kind gifts from Takeda Pharmaceutical Co (Osaka, Japan), Ono Pharmaceutical Co (Osaka, Japan) and Novartis Pharmaceutical (Basel, Switzerland), respectively Human recombinant IL-7 was purchased...
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Báo cáo y học:

Báo cáo y học: " Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice" ppt

... as: Imhof et al.: Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice Arthritis Research & Therapy 2011 13:R97 Submit your ... M, Miyata K: Inhibitory effects of a selective endothelin- A receptor antagonist YM598 on endothelin- 1-induced potentiation of nociception in formalin-induced and prostate cancerinduced pain models ... of inflammatory mediators [21,25-32] Given the availability of potent endothelin receptor antagonists, we investigated the effects of systemic administration of the mixed ETA and ET B endothelin...
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CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF LIGUSTICUM WALLICHII EXTRACT IN 3t3 l1 AND HEP g2 CELL LINES

CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF LIGUSTICUM WALLICHII EXTRACT IN 3t3 l1 AND HEP g2 CELL LINES

... EFFECTS OF PHTHALIDES ON 3T3- L1 CELL LINE Hypothesis Phthalides extracts from chuangxiong influence preadipocyte proliferation and differentiation in 3T3- L1 murine cell model Introduction According ... duplication and cell division The increase of sub-G1 phase from cell cycle analysis showed that IPE had a minor or insignificant influence on apoptosis induction in Hep- G2 cells In contrast, ... via interfering cell cycle development but the underlying mechanisms remain unknown In the current findings, the growth of Hep- G2 cells was inhibited after treated with IPE Furthermore, the inhibition...
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Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc

Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc

... recipients of IND drugs, medical monitoring and reporting of the use of such drugs, information about shipment and storage of drugs, disposition of unused IND drugs, and submission of annual and other ... changes in the Office of the Secretary of iii iv The Acquisition of Drugs and Biologics for CBW Defense Defense (OSD) to centralize the authority for interactions between DoD and FDA The interviews ... and Biologics for CBW Defense cals (drugs) , and the protection of personnel by immunization, mainly by vaccines The objective of the U.S Department of Defense (DoD) in the acquisition of drugs and...
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Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot

Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot

... two-dimensional NMR spectroscopy The data clearly indicated that the tx 5a glycan is in an a- D-Gal-(1fi3) -a- D-GalNAc configuration Taken together, these data demonstrate that two Conus glycopeptides ... glycosylated at position Taken together, these data identified the glycan as a- D-Gal-(1fi3 )a- D-GalNAc There are several NOEs between the glycan and the glycopeptide side-chain atoms of tx 5a, which ... b-D-Gal-(1fi3) -a- D-GalNAc containing glycopeptide, and native tx 5a were simultaneously incubated and reacted with the same vial of the enzyme b-galactosidase Native tx 5a, tx 5a hydrophilic, and tx5a...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt

Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt

... purpose of this guide is to provide emergency first responders with information that should aid them in the selection and utilization of chemical and/ or biological (CB) decontamination equipment The ... Justice Programs National Institute of Justice Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders NIJ Guide 103–00 Volume I Dr Alim A Fatah1 ... recognizing the needs of State and local emergency first responders, the Office of Law Enforcement Standards (OLES) at the National Institute of Standards and Technology (NIST), working with the National...
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Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf

Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf

... Decontamination Equipment for Emergency First Responders, includes details on the 72 decontamination equipment items that are referenced in Volume I The Guide for the Selection of Chemical and Biological Decontamination ... Volume II of the Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders Volume II includes three sections and five appendices Section is the introduction ... recognizing the needs of State and local emergency first responders, the Office of Law Enforcement Standards (OLES) at the National Institute of Standards and Technology (NIST), working with NIJ, the...
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Báo cáo y học:

Báo cáo y học: " Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat protein" docx

... 0.0 B -Tat C -Tat No Tat 20 200 B -Tat 20 200 C -Tat No Tat Conc of Tat ( ng/ml ) Figure Discordance between the Transactivation and cytokine induction functions of Tat Discordance between the Transactivation ... Interestingly, subtype-C Tat protein is naturally devoid of the RGD motif [1] and absence of this motif may adversely affect cell attachment of C -Tat and the subsequent internalization We are presently ... biological functions An enormously large number of biological functions has been ascribed to Tat [30] Most often only the transactivation property of Tat is used to test the quality of Tat We emphasize...
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Aggregation enhanced two photon excited photoluminescence of noble metal nanoparticles and their chemical and biological applications

Aggregation enhanced two photon excited photoluminescence of noble metal nanoparticles and their chemical and biological applications

... optical properties of noble metal nanoparticles and two- photon photoluminescence, the aggregation of noble 32 metal nanoparticles induced enhanced two- photon photoluminescence and their applications ... photoluminescence of noble metal nanoparticles Firstly, two- photon excited photoluminescence and two- photon induced singlet oxygen generation of Au nanospheres and two ratios of Au nanorods before and after aggregation ... microfabrication,129 two- photon excited imaging,130 two- photon excited photoluminescence, 131, 132 and two- photon related chemical and biological applications. 133, 134 These interesting and potentially useful applications...
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Application of conjugated polymers in chemical and biological detections

Application of conjugated polymers in chemical and biological detections

... APPLICATION OF CONJUGATED POLYMERS IN CHEMICAL AND BIOLOGICAL DETECTIONS REN XINSHENG (B SC., Shandong University, China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... vinylene) in conjugation of biotin-dimethyl viologen and avidin in water (56) In the absence of avidin, the small biotin group in B-MV would not hinder association of the viologen portion of B-MV ... with conjugated polymers, and thus the conjugated polymer would result in strong fluorescence quenching But in the presence of avidin, the avidin can bind with the biotin group in B-MV and thus...
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