... consequence of the displacement of bound proteins from the singlestranded overhang, chiefly hPOT1, as well as possible uncapping of telomerase from the ends There are likely to be multiple mechanisms involved, ... such as diethylamine, pyrrolidine or piperidine Structure-based drug discovery does have these few structures as starting points [42–47], although these also indicate that the flexibility of the ... A431 human epithelial carcinoma MDA-MB-231 human breast cancer MIA PaCa-2 human pancreatic cancer UXF1138L human uterine carcinoma M14, LP, LM melanoma RHPS4b CG5 breast carcinoma Quarfloxin Quarfloxin...