ROMP based polymer nanoparticles for the targeted delivery of antitumor agents
ROMP based polymer nanoparticles for the targeted delivery of antitumor agents
... Institute for BioNanotechnology in Medicine Advantages of Polymer Therapeutics “Using advanced polymer chemistry and precision engineering at the molecular level, together with an appreciation of the ... favors polymer formation due to the alleviation of ring strain • Highly functional group tolerant, works at mild temperature • Amenable to the synthesis of monodisperse block copolymers Institute for ... Components of drug delivery system should easily be removed from the organism Institute for BioNanotechnology in Medicine Polymeric Nanoparticles as Model Drug Delivery Vehicles Institute for BioNanotechnology...
- 53
- 501
- 0
báo cáo khoa học: " Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts" potx
... (pH 7.4) For siRNA delivery experiments, protoplasts were cultured in cell wall regeneration medium siRNA delivery to protoplasts and intact BY-2 cells Protoplasts (1 × 106mL-1) or intact BY-2 cells ... SL, Papahadjopoulos D: Liposome-mediated delivery of tobacco mosaic virus RNA into tobacco protoplasts: A sensitive assay for monitoring liposome-protoplast interactions Proc Natl Acad Sci USA ... doi:10.1186/1471-2229-10-291 Cite this article as: Silva et al.: Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts BMC Plant Biology 2010 10:291 ...
- 14
- 295
- 0
Sampling on energy norm based sparse grids for the optimal recovery of Sobolev type functions in Hγ
... meaning to point evaluations of functions it is essential that the spaces under consideration contain only continuous functions To be more precise, they contain equivalence classes of functions ... section we recall the definition of the function spaces under consideration here They α (Td ) are all of Sobolev- type In a first subsection we consider the periodic Sobolev spaces Hmix of dominating ... some of them concerning the used approximating operators on the other hand 19 5.1 The mixed-mixed case α (Td ) measuring the error in H γ (Td ) We consider sampling operators for functions in Hmix...
- 33
- 311
- 0
In vitro and in vivo evaluation of transferrin conjugated lipid shell and polymer core nanoparticles for targeted delivery of docetaxel
... IN VITRO AND IN VIVO EVALUATION OF TRANSFERRIN- CONJUGATED LIPID SHELL AND POLYMER CORE NANOPARTICLES FOR TARGETED DELIVERY OF DOCETAXEL PHYO WAI MIN (M.B.,B.S (YGN) U.M(1)) ... the synthesis and characterization of transferrin conjugated lipid shell and polymer core nanoparticles are discussed in Chapter In Chapter 5, in vitro cellular study of transferrin conjugated LPNPs ... Organization In this thesis, formulations of lipid shell and polymer core nanoparticles are developed for the clinical administration of docetaxel At the same time, the effect of different lipids used in...
- 129
- 286
- 0
báo cáo hóa học: " Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector" ppt
... the rate of Cu release (see Discussion) In vitro toxicity of CuCNPs in HeLa cells The in vitro toxicity of CuCNPs in HeLa cells (a cervical adenocarcinoma) was investigated via an assay based ... platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector Nanoscale Research Letters 2011 6:445 Submit your manuscript ... metal binding properties of our Cu-binding particles, as well as preliminary in vitro toxicity in cancer cells Page of 10 Results Synthesis and characterization of Cu-loaded polymeric nanoparticles...
- 10
- 495
- 0
Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs
... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CONTROLLED AND TARGETED DELIVERY OF PROTEIN DRUGS SMALL AND MOLECULE DRUGS BY LEE SIE HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF ... backbone of PLA and PLGA to form PLA-TPGS and PLGA-TPGS block copolymers These block copolymers are an example of amphiphiles Their uses as different carriers for delivery of protein and anticancer ... Peptide /protein drug delivery 15 2.2.1 Structural aspect of protein 15 2.2.2 Challenges in peptide /protein drug delivery 17 2.2.3 Approaches for delivery of peptide /protein drugs...
- 118
- 353
- 0
Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain
... Functions of the Blood Brain Barrier The main function of the blood brain barrier is to protect the brain The BBB serves as an impermeable wall to prevent the entry of agents from outside of the brain ... Anatomy of the Blood Brain Barrier 1.1.2 Functions of the Blood Brain Barrier 1.1.3 Clinical Significance of the Blood Brain Barrier 1.2 METHODS TO OVERCOME THE BLOOD BRAIN BARRIER 1.3 NANOPARTICLES ... polymers to deliver drugs across the blood brain barrier and the surface coating plays key roles in determining the extent of the particles to cross the BBB To further investigate the potential for the...
- 93
- 257
- 0
ag doped wo3-based powder sensor for the detection of no gas in air
... measured in a ¯owing stream of pure air or in 40 ppm NO in air (60:40 mixture from an air cylinder with another cylinder (BOC special gases) containing ca 100 ppm NO balanced with air) by the ac ... concentration of NO and NO2 gases because of the low concentration, one of the roles of the Ag is apparent to provide surface for the conversion of NO to NO2 according to the literature [18] It is worth noting ... However, there is limited work reported in the literature on addressing the precise sensing mechanism for the NOx gases detection over WO3-based sensors and there is no work to reveal the roles of the...
- 8
- 502
- 0
THE ATTRACTIONS OF RISK-BASED REGULATION: ACCOUNTING FOR THE EMERGENCE OF RISK IDEAS IN REGULATION docx
... The Attractions of Risk- based Regulation: accounting for the emergence of risk ideas in regulation Bridget M Hutter Contents Introduction The Emergence of Risk- based Regulation: ... purchaser Printed and bound by Printflow, March 2005 The Attractions of Risk- based Regulation: accounting for the emergence of risk ideas in regulation1 Bridget M Hutter Introduction Recent decades ... furthered the prominence of risk discourses and the promotion of riskbased thinking in government However, the emergence of ideas about risk in the regulatory arena is more one of drift than domination...
- 21
- 533
- 0
solgel based hydrothermal method for the synthesis of 3d flowerlike zno microstructures
... patterns of the ZnO sample synthesized at 120 ◦C for 17 h hydrothermal treatment Figure a b d e c f Fig SEM images of the time-dependent evolution in the formation of 3D flower-like ZnO synthesized ... of the formation process of the 3D flower-like ZnO Figure Fig (a) Bar graph illustration of the photocatalytic degradation of KGL using ZnO samples synthesized at 120 ◦C for different hydrothermal ... order to further study the effects of the hydrothermal treatment temperature on the ZnO product, samples were also synthesized at 90 ºC and 150 ºC for 17 h The morphologies of the ZnO samples...
- 26
- 551
- 0
báo cáo hóa học: " Glrt-Based Array Receivers for The Detection of a Known Signal with Unknown Parameters Corrupted by " docx
... that a TNAR is available in this latter case A Unknown parameters (µs, φs) and known total noise (R, C) Under the assumptions A1 and A2 , assuming known parameters R, C and s and unknown parameters ... performance In a same way, the O9 detector, which assumes that all the parameters of the sources are unknown, has the lowest performance Moreover, for a given set of unknown desired signal parameters, ... GLRT-BASED ARRAY RECEIVERS FOR THE DETECTION OF A KNOWN SIGNAL WITH UNKNOWN PARAMETERS CORRUPTED BY NONCIRCULAR INTERFERENCES Pascal Chevalier(1)(2)*, Abdelkader Oukaci(3), Jean-Pierre Delmas(3)...
- 45
- 467
- 0
Báo cáo hóa học: " Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4methoxyphenyl)-1H-indole-2-carboxylate" doc
... supervised the organic synthesis and compound characterization and participated in the draft of the manuscript LAVS was responsible for the antitumoral evaluation of the compound EP supervised the studies ... membranes of to KDa and 12 to 14 KDa These results may be important for future drug delivery applications using nanoliposomes for the encapsulation and transport of this promising antitumoral ... responsible for the interpretation of results, and drafted the manuscript ASA carried out the liposome preparation, the DLS and zeta potential measurements and dialysis experiments in liposomes M-JRPQ and...
- 6
- 323
- 0
Báo cáo hóa học: " Split SR-RLS for the Joint Initialization of the Per-Tone Equalizers and Per-Tone Echo Cancelers in DMT-Based Receivers" doc
... /κ = 25, λ = 0.997, and µ = Figure 5: Learning curves for the joint PTEQ and PTEC initialization using the original SR-RLS and split SR-RLS scheme The curves are simulated for upstream CSA loops ... Iteration/20(symbols) Figure 4: Learning curves for the joint PTEQ and PTEC initialization using the original SR-RLS and split SR-RLS scheme The curves are simulated for downstream CSA loops with TEQ ... research interests are in the area of digital signal processing for telecommunications Split SR-RLS for Joint PTEQ/PTEC Initialization in DMT Receivers Marc Moonen received the Electrical Engineering...
- 13
- 344
- 0
Báo cáo tin học: "Graph-based upper bounds for the probability of the union of events" ppt
... inequalities for the probability of a logical function of events, The American Mathematical Monthly, 72 (1965), 343 - 359 [6] D Hunter, An upper bound for the probability of the union, J Appl ... matrix H the order of the elements will follow the lexicographic order of the subscript sets The Boolean probability bounding problem can thus be restated as a linear program of the form M ax ... we can trivially set J⊆V the upper bound to Therefore the first row of the matrix Has well as the first column corresponding to the variable x∅ can be disregarded from our formulation In (1) we now...
- 11
- 364
- 0
báo cáo khoa học: "A homoharringtonine-based induction regimen for the treatment of elderly patients with acute myeloid leukemia: a single center experience from China" pptx
... results of HA are comparable with these and other reported results in elderly patients with AML [15-21] The response rates of HA are also comparable with the data of elderly patients treated with DA ... the SPSS 13.0 software Results Characteristics of the patients Characteristics of the patients at the time of diagnosis are listed in Table The median age of these patients was 70 (60–84) years ... Coso D, Bardou VJ, Stoppa AM, Braud AC, Bouabdallah R, Sainty D, Mozziconacci MJ, Lafage M, Damaj G, Blaise D, Gastaut JA, Maraninchi D: The benefit of induction chemotherapy in patients age > or...
- 5
- 349
- 0
Từ khóa: Báo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ