ROMP based polymer nanoparticles for the targeted delivery of antitumor agents

... Institute for BioNanotechnology in Medicine Advantages of Polymer Therapeutics “Using advanced polymer chemistry and precision engineering at the molecular level, together with an appreciation of the ... favors polymer formation due to the alleviation of ring strain • Highly functional group tolerant, works at mild temperature • Amenable to the synthesis of monodispers...

Ngày tải lên: 23/08/2015, 18:48

... (pH 7.4) For siRNA delivery experiments, protoplasts were cultured in cell wall regeneration medium siRNA delivery to protoplasts and intact BY-2 cells Protoplasts (1 × 106mL-1) or intact BY-2 cells ... SL, Papahadjopoulos D: Liposome-mediated delivery of tobacco mosaic virus RNA into tobacco protoplasts: A sensitive assay for monitoring liposome-protoplast interaction...

Ngày tải lên: 11/08/2014, 11:21

... meaning to point evaluations of functions it is essential that the spaces under consideration contain only continuous functions To be more precise, they contain equivalence classes of functions ... section we recall the definition of the function spaces under consideration here They α (Td ) are all of Sobolev- type In a first subsection we consider the periodic Sob...

Ngày tải lên: 14/10/2015, 15:25

... IN VITRO AND IN VIVO EVALUATION OF TRANSFERRIN- CONJUGATED LIPID SHELL AND POLYMER CORE NANOPARTICLES FOR TARGETED DELIVERY OF DOCETAXEL PHYO WAI MIN (M.B.,B.S (YGN) U.M(1)) ... the synthesis and characterization of transferrin conjugated lipid shell and polymer core nanoparticles are discussed in Chapter In Chapter 5, in vitro...

Ngày tải lên: 09/10/2015, 11:18

... the rate of Cu release (see Discussion) In vitro toxicity of CuCNPs in HeLa cells The in vitro toxicity of CuCNPs in HeLa cells (a cervical adenocarcinoma) was investigated via an assay based ... platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery...

Ngày tải lên: 21/06/2014, 02:20

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CONTROLLED AND TARGETED DELIVERY OF PROTEIN DRUGS SMALL AND MOLECULE DRUGS BY LEE SIE HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF ... backbone of PLA and PLGA to form PLA-TPGS and PLGA-TPGS block copolymers These block copolymers are an example of amphiphiles Their uses as different carri...

Ngày tải lên: 26/11/2015, 22:41

... Functions of the Blood Brain Barrier The main function of the blood brain barrier is to protect the brain The BBB serves as an impermeable wall to prevent the entry of agents from outside of the brain ... Anatomy of the Blood Brain Barrier 1.1.2 Functions of the Blood Brain Barrier 1.1.3 Clinical Significance of the Blood...

Ngày tải lên: 26/11/2015, 22:48

... measured in a ¯owing stream of pure air or in 40 ppm NO in air (60:40 mixture from an air cylinder with another cylinder (BOC special gases) containing ca 100 ppm NO balanced with air) by the ac ... concentration of NO and NO2 gases because of the low concentration, one of the roles of the Ag is apparent to provide surface for the conversion of N...

Ngày tải lên: 19/03/2014, 16:47

... The Attractions of Risk- based Regulation: accounting for the emergence of risk ideas in regulation Bridget M Hutter Contents Introduction The Emergence of Risk- based Regulation: ... purchaser Printed and bound by Printflow, March 2005 The Attractions of Risk- based Regulation: accounting for the emergence of risk ideas in...

Ngày tải lên: 23/03/2014, 00:20

... patterns of the ZnO sample synthesized at 120 ◦C for 17 h hydrothermal treatment Figure a b d e c f Fig SEM images of the time-dependent evolution in the formation of 3D flower-like ZnO synthesized ... of the formation process of the 3D flower-like ZnO Figure Fig (a) Bar graph illustration of the photocatalytic degradation of KGL using ZnO samples s...

Ngày tải lên: 06/05/2014, 13:26

... that a TNAR is available in this latter case A Unknown parameters (µs, φs) and known total noise (R, C) Under the assumptions A1 and A2 , assuming known parameters R, C and s and unknown parameters ... performance In a same way, the O9 detector, which assumes that all the parameters of the sources are unknown, has the lowest performance Moreover, for a...

Ngày tải lên: 21/06/2014, 00:20

... supervised the organic synthesis and compound characterization and participated in the draft of the manuscript LAVS was responsible for the antitumoral evaluation of the compound EP supervised the studies ... membranes of to KDa and 12 to 14 KDa These results may be important for future drug delivery applications using nanoliposomes for the encapsulation...

Ngày tải lên: 21/06/2014, 01:20

... /κ = 25, λ = 0.997, and µ = Figure 5: Learning curves for the joint PTEQ and PTEC initialization using the original SR-RLS and split SR-RLS scheme The curves are simulated for upstream CSA loops ... Iteration/20(symbols) Figure 4: Learning curves for the joint PTEQ and PTEC initialization using the original SR-RLS and split SR-RLS scheme The cur...

Ngày tải lên: 23/06/2014, 01:20

... inequalities for the probability of a logical function of events, The American Mathematical Monthly, 72 (1965), 343 - 359 [6] D Hunter, An upper bound for the probability of the union, J Appl ... matrix H the order of the elements will follow the lexicographic order of the subscript sets The Boolean probability bounding problem can thus be restated as...

Ngày tải lên: 07/08/2014, 15:23

... results of HA are comparable with these and other reported results in elderly patients with AML [15-21] The response rates of HA are also comparable with the data of elderly patients treated with DA ... the SPSS 13.0 software Results Characteristics of the patients Characteristics of the patients at the time of diagnosis are listed in Table The me...

Ngày tải lên: 10/08/2014, 22:20