... localization of GLUT8 in testis, (b) elucidate the role of APs in GLUT8 sorting, and (c) understand the role of the EXXXLL motif in GLUT8 sorting. The data provide evidence that endogenous GLUT8 co-localizes ... recombinant AP subunits [19,20].However, the findings have been contradictory withregard to localization of the endogenous GLUT8 in tes-tis, the nature of its sorting, and the interaction of its ... ⁄ lysosomal sorting signal [4]. GLUT8 is mainly expressed in testis and to a lesserextent in brain [11,12]. Contradictory data existregarding its localization in the tissues in which it is most...