... sensitivity analyses incorporating clinically sensible variations Analysis with no sensitivity analysis Int J Med Sci 2007, Expert opinion without explicit critical appraisal, or based on physiology, ... analyses SR (with homogeneity*) of Level economic studies Analysis based on clinically sensible costs or alternatives; systematic review(s) of the evidence; and including multi-way sensitivity ... control studies are surely more appropriate, remaining clearly defined in any of these study inclusion and exclusion criteria adopted [14,15] Nowadays, the majority of today's clinical practice...