... non-progressorLeon Caly1, Nitin K Saksena2, Sabine C Piller3,4 and David A Jans*1Address: 1Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia, 2Retroviral ... levels significantly reduced comparedto wildtype (Fig. 1B). Sequence analysis revealed that allclones with reduced nuclear accumulation (Vpr A6 -2 and Vpr A6 -3/5) contained a phenylalanine to leucine ... defense against viral attack. Nat Immunol 2004, 5:1109-1115.48. Wang B, Dyer WB, Zaunders JJ, Mikhail M, Sullivan JS, Williams L,Haddad DN, Harris G, Holt JA, Cooper DA, Miranda-Saksena M, Boa-dle...