... toxicants. Interspecies variability can be brokendown into a series of factors:• Differences in uptake–elimination kinetics• Differences in internal sequestering mechanisms• Differences in biotransformation ... in any form or by any means, electronicor mechanical, including photocopying, microfilming, and recording, or by any information storage orretrieval system, without prior permission in writing ... OutlookBy arranging the chapters within these sections, the different focuses of the chaptersare presented.We can help in managing the remaining risks only a bit further, by stating thatour discussions...