ROLE OF RAP1 IN ANGIOGENESIS AND TUMOR INVASION

... suggest that Rap1, although not as strong an oncogene as Ras, plays an important role in the tumorigenic process. 3.2. Rap1 and tumor invasion and metastasis The role of Rap1 in tumor metastasis, ... dissection of the precise roles of Rap1 in different cancer types. 3.3. Rap1 and brain tumors 3.3.1. Brain tumor overview Although brain tumors re...

Ngày tải lên: 24/08/2014, 13:33

... culled. No information is available on the costs of culling, diagnostic testing of samples, cleaning and disinfection, and other administrative costs (Obi, Oparinde, and Maina 2008). Regarding the ... their role in poultry rearing, women should also be encouraged to be actively involved in training programs and in dissemination of information regarding biosecurity te...

Ngày tải lên: 21/02/2014, 01:20

... Replacement of terminal cys- teine with histidine in the metallothionein a and b domain maintains its binding capacity. Eur J Biochem 259, 519–527. R. Bofill et al. C. elegans CeMT1 and CeMT2 metallothioneins FEBS ... P17512). The coordinat- ing and putative coordinating residues are highlighted (Cys in grey shadow, His and Tyr in bold) and the total content in each peptide...

Ngày tải lên: 07/03/2014, 02:20

... The interaction of EspL2 with Annexin A2 increases F-actin bundling activity and strengthens the membrane–cytoskel- eton linkage, resulting in the condensation of actin fibers and the induction of ... (T3SS) and modulates cellular func- tion [2]. Injected Tir is localized in the host-cell membrane and forms a receptor for intimin. Binding of intimin to the extracellular dom...

Ngày tải lên: 29/03/2014, 09:20

... Nevertheless, explaining aging in terms of one universal, driving force is not entirely unrealistic in view of the universality of the principles behind the living world on this planet. In spite of its bewildering ... way of interrupting the pathway of mutation accumulation increasing the chance of sexual reproduction to produce high-fitness off- spring. In this case, sen...

Ngày tải lên: 11/06/2014, 10:21

... expression of miR-181a, miR-181b, and miR-213 in OVCA cell lines results in resistance to doxorubicin and gemcitabine and increased expression of miR-99b and miR-14 leads to docetaxel and paclitaxel ... overexpression of miR-375 resulted in sup- pressed glucose-stimulated insulin secretion and its inhi- bition resulted in enhanced insulin secretion. Myotrophin, a pro...

Ngày tải lên: 20/06/2014, 07:20

... that code for proteins from the family of neurexins and neuroligins that play, in turn, a role in the development and functioning of synaptic and in particular glutamatergic and GABA-ergic networks ... El-Husseini, 2006; Buchsbaum, 2009). The first X-linked mutations in genes involved in the coding of neuroligin were revealed in patients with autism in two Sw...

Ngày tải lên: 28/06/2014, 05:20

... report increased levels of leptin during infectious and inflammatory processes. Leptin expression in adipose tissue and circulating leptin levels are increased after administration of inflammatory ... leptin, adiponectin and resistin, as well as cytokines and chemokines. Altered levels of different adipo- cytokines have been observed in a variety of inflammatory conditions...

Ngày tải lên: 09/08/2014, 08:22

... capital profitability is declining. The internalization of information within the same institution may thus enhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing. The ... placing money with investment financial institutions in the capital market, and hold the remaining share in non- interest bearing, short-term bank deposits (eq. 7). The share...

Ngày tải lên: 24/10/2012, 09:33