FUNCTIONAL INSIGHTS INTO ONCOGENIC PROTEIN TYROSINE PHOSPHATASES BY MASS SPECTROMETRY
Báo cáo khoa học: Protein tyrosine phosphatases: functional inferences from mouse models and human diseases pot
... represent
hyperactive mutants of protein tyrosine kinases found
in the genome and thus distort the delicate phospho-
tyrosine balance within cells. Protein tyrosine phospha-
tases (PTPs), by virtue of their ... (2008) Pro-
tein tyrosine phosphatases: regulatory mechanisms.
FEBS J 275, 831–847.
2 Pulido R & Hooft van Huijsduijnen R (2008) Protein
tyrosine phosphatases:...
Báo cáo Y học: Coordinated action of protein tyrosine phosphatases in insulin signal transduction potx
... remains to be determined.
Ó FEBS 2002 Protein tyrosine phosphatases in insulin signaling (Eur. J. Biochem. 269) 1055
MINIREVIEW
Coordinated action of protein tyrosine phosphatases
in insulin signal ... deactivation of insulin
receptor substrate-1 by protein- tyrosine phosphatase 1B. Possible
facilitation by the formation of a ternary complex with th e Grb2
adaptor protein....
Báo cáo khoa học: Protein tyrosine phosphatases: structure–function relationships ppt
... motif; LMW-PTP, low molecular weight protein tyrosine phosphatase; N-SH2, N-terminal SH2 domain; PTP, protein
tyrosine phosphatase; RPTP, receptor protein tyrosine phosphatase; YopH, Yersinia ... human protein tyrosine phosphatase 1B.
Science 263, 1397–1404.
7 Jia Z, Barford D, Flint AJ & Tonks NK (1995) Struc-
tural basis for phosphotyrosine peptide recognition by
prot...
Báo cáo khoa học: Structural and functional insights into Erwinia carotovora L-asparaginase ppt
... A
˚
2
) found
in protein protein complexes [26]. The shape comple-
mentarity S
c
[27] of the two tetramers is 0.517, which
corresponds to the lower limit of S
c
found in protein
protein interfaces. ... growth. The hydrophobic inter-
actions were not taken into consideration, although
they are very important in evaluating the stability of
protein protein complexes. However, the calcul...
Báo cáo y học: " Multi-stage Friend murine erythroleukemia: molecular insights into oncogenic cooperation" doc
... erythroleukemogenesis by inhibit-
BioMed Central
Page 1 of 11
(page number not for citation purposes)
Retrovirology
Open Access
Review
Multi-stage Friend murine erythroleukemia: molecular insights into
oncogenic ... induces
receptor dimerization followed by the activation of the
intrinsic tyrosine kinase and receptor transphosphoryla-
tion on specific tyrosine residues [111,112]...
Tài liệu Báo cáo khoa học: A functional polymorphism of apolipoprotein C1 detected by mass spectrometry docx
... polymorphism of apolipoprotein C1
FEBS Journal 273 (2006) 4707–4715 ª 2006 The Authors Journal compilation ª 2006 FEBS 4711
A functional polymorphism of apolipoprotein C1 detected
by mass spectrometry
Matthew ... of
ApoC1 as well as some protein properties that suggest
the functional significance of this residue change. They
Keywords
apolipoprotein C1; mass spectrometry;
polymo...
protein and peptide analysis by mass spectrometry
... Resonance Mass Spectrometry VCH, Wemheim, Germany
15 Busch, K. L., Glish, G. L., and McLuckey, S. A. (1988) Mass Spectrometry /Mass
Spectrometry Technzques and Applications of Tandem Mass Spectrometry ... Combined liquid chromatography mass spectrometry Part II
Techniques and mechanisms of thermospray Mass Spectrom Rev 9,63 l&669
9 Dawson, P H (1976) Quadrupole Ma...
Tài liệu Báo cáo khoa học: Si-face stereospecificity at C5 of coenzyme F420 for F420H2 oxidase from methanogenic Archaea as determined by mass spectrometry ppt
... stereospecificity at C5 of coenzyme F
420
for F
420
H
2
oxidase from methanogenic Archaea as determined by
mass spectrometry
Henning Seedorf
1
,Jo
¨
rg Kahnt
1
, Antonio J. Pierik
2
and Rudolf K. Thauer
1
1 ... spectra (white). For
better visibility in the structures deuterium is abbreviated by D
rather than by
2
H and hydrogen by H rather than
1
H. Mtd, Si-face-
specific F
420
-dep...
Báo cáo khoa học: A mutagenic analysis of the RNase mechanism of the bacterial Kid toxin by mass spectrometry pptx
... time-of-flight mass spectrometer (Micromass
LC-T; Waters, Manchester, UK) modified for high mass
operation and operating in positive ion mode [32]. To
monitor RNA cleavage by Kid protein a robotic ... methods). Protein syn-
thesis was inhibited by the wild-type Kid protein, the
KidT69G mutant and to a lesser extent by KidA55G
(Fig. 4). The double mutant KidA55G ⁄ T69G was also
ab...
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