Báo cáo y học: "Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions" ppsx
Báo cáo y học: "Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions" ppsx
... R80
Research
Developmental roles of 21 Drosophila transcription factors are
determined by quantitative differences in binding to an overlapping
set of thousands of genomic regions
Stewart MacArthur
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, Xiao-Yong ... being with the D-V
Broad, overlapping patterns of binding of transcription factors to the genome in blastoderm embryos...
Báo cáo Y học: Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system docx
... protease inhibitors, and then the
level of Tob protein was analyzed by Western blotting
with an antibody against Tob (Fig. 1A). Treatment of
HeLa cells with the proteasome inhibitors MG115 and
MG132 ... and the protein levels of BTG/Tob proteins and b-actin
were analyzed by Western blotting with antibodies against T7-tag and
actin, respectively. Nonspecific bands are indicated wi...
Báo cáo y học: "Ethnobotanical study of indigenous knowledge on medicinal plant use by traditional healers in Oshikoto region, Namibia" pdf
... treatment of head-
ache. Pergularia daemia is found to be useful as
anthelmintic, laxative, anti-pyretic, expectorant, and
used in infantile diarrhoea [35]. The anti-inflammatory,
anti-pyretic and analgesic ... community healthcare and drug
development in the present and future [4]. Since the
beginning of this Century, there has been a n increasing
interest in the study of medic...
Báo cáo khoa học: The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain pptx
... to the tandem GAF
domain of PDE10, and by cGMP when linked to the
tandem GAF domain of PDE2, )5or)11. The bio-
chemical properties of signalling by human tandem
GAF domains to cyaB1 AC were by ... signalling pathways in essentially all cells
[1]. Their intracellular levels are balanced by the
rates of biosynthesis via adenylyl cyclase (EC 4.6.1.1)
and guanylyl cyclas...
Báo cáo y học: "γ Paradoxical roles of IFN-γ in models of Th1-mediated autoimmunity" potx
... com-
plexities are perhaps best demonstrated in the analysis of
the role of IFN-γ in models of autoimmunity. Early attempts
to define the role of IFN-γ in autoimmunity by the adminis-
tration of IFN-γ ... be a compensatory
increase in Th2 cytokines, such as IL-4 and IL-10, no evi-
dence for enhanced expression of any of the Th2
Table 1
Role of IFN-
γγ
in variou...
Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx
... mammalian families of NF-κB and IκB polypeptides. Conserved domains and their primary functions are indicated. Ankyrins, ankyrin repeat
domain (functions by binding and inhibiting RHDs; Bcl-3 and ... outlined the advantages and
disadvantages of anti-inflammatory and anti-rheumatic NF-κB
inhibitors, and the effects (in animal models of RA and other
autoimmune diseases) of geneti...
Báo cáo y học: "Possible roles of Epstein-Barr virus in Castleman disease" potx
... obtained to examine the presence of EBV and its localization by hematoxylin-eosin
stain, immunohistochemistry, polymerase chain reaction and In- situ hybridization
Results: Hyaline-vascular type ... Keller defined Castleman disease both
clinically and histologically.[2] It has 2 clinical types, uni-
centric and multicentric and 3 histologic types, hyaline-
vascular type, plasma cell ty...
Báo cáo y học: "Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model" pptx
... CD4
+
T cells in the spleen were defined as Tfh by
expression of a combination of surface markers (CXCR5,
PD-1 and ICOS), transcription factors (Bcl-6) and by their
cytokine profile (IL -21) . In contrast, ... not fully
understood. Perforin, granzyme A, and granzyme B are
effector molecules of the granule exocytosis pathway that
are mainly produced by CD8
+
T cells and...
Báo cáo y học: "The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression" ppt
... having more binding sites available to bind to,
which in turn means a greater probability of binding and thus
repression. In contrast, the reduced repression of a single pair
of overlapping binding ... targeted by the same miRNAs separated by a given distanceFigure 3
Frequency of pairs of binding sites targeted by the same miRNAs
separated by a given dista...
Báo cáo y học: "A review of anatomical and mechanical factors affecting vertebral body integrit
... play an
important role in maintaining static equilibrium of the trunk by resisting the flexion moment imposed
by gravity and any mass carried anterior to the spine (see figure 2). The role of ... potential to make measurements of bone geometry and
bone quality [22, 26, 48, 49].
Clinically, the advantages offered by QCT and MRI may be offset by the greater expense, lon...
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