Báo cáo y học: "hese authors contributed equally to this work" potx

... Palaeontology and Geology, East Beijing Road, Nanjing, Jiangsu 210008, PR China. ¤ These authors contributed equally to this work. Correspondence: Junfeng Zhang. Email: jfzhang@nju.edu.cn. Chen-Yu ... microarray hybridization and array scanning were performed as previously described [21]. Briefly, 25 μg of total RNA was used to isolate the low molecular weight RNA using polyethy...

Ngày tải lên: 14/08/2014, 21:20

... including mature parasite-infected erythrocyte surface antigen (MESA - known to bind to the erythrocyte membrane cytoskeleton) http://genomebiology.com/2005/6/11/R93 Genome Biology 2005, Volume 6, Issue 11, ... the erythrocyte mem- brane and mediate cytoadhesion to human receptors exposed to circulating parasites. PfEMP1 proteins are encoded by var genes, and field isolates possess ap...

Ngày tải lên: 14/08/2014, 15:20

... Tschopp J: Inflammatory caspases: linking an intra- cellular innate immune system to autoinflammatory diseases. Cell 2004, 117:561-574. 33. Martinon F, Tschopp J: Inflammatory caspases and inflammas- omes: ... activates transcription factors such as nuclear factor-κB (NF-κB) and interferon regulatory factors (IRFs) that ultimately lead to tumor necrosis factor (TNF) and type I interferon...

Ngày tải lên: 14/08/2014, 20:22

... mediates Myc autorepression and its tran- scriptional control at many loci. In this study the authors used the Gal4 UAS system to express ectopic dmyc in embryos and performed microarray analysis to ... cuticle hydrolase activity transferase activity ion transporter activity carrier activity structural constituent of cytoeskeleton microtubule motor activity nucleoside binding hydrolas...

Ngày tải lên: 14/08/2014, 20:22

... patient safety measure. A potential benefit of implementing an MET is the capacity to systematically assess preventable adverse events, which are defined as poor outcomes caused by errors or system design ... Emergency Teams (METs), alternatively known as Rapid Response Teams, have recently been implemented in many hospitals worldwide [1]. The primary role of an MET is to improve the earl...

Ngày tải lên: 25/10/2012, 10:06

... mainly cytostati- cally compared with classical cytotoxic drugs require special timing of scans [68]. International guidelines for PET tests are therefore necessary to guarantee the quality and ... conditions, are likely to play a key role in future clinical cancer treatment. Table 2. Tumor types for which FDG-PET assays are used to assess tumor response to cancer drug therapy...

Ngày tải lên: 25/10/2012, 11:10

... Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of 13.3 kDa, belonging to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated ... of the steady-state serum trough concentrations of digoxin in Japanese patients. Forty patients treated with digoxin and 56 healthy elderly subjects were participated in this study. Th...

Ngày tải lên: 31/10/2012, 17:08

... analysis of the entire set of chimeras prepared in this study, which allowed us to assay directly the condensation activity of the isolated (His) 6 -FAE1 KCSs [20]. We used this assay to verify ... monounsaturated fatty acids were elongated by the FAE1 KCSs to a greater degree than were saturated fatty acids. This may reflect the available substrates in this yeast system and/or t...

Ngày tải lên: 21/02/2014, 15:20

... atively unfo lded proteins is i ndirectly con- ®rmed by their extremely h igh s ensitivity to protease degradation in vit ro [4,5,54±59]. Table 1. Hydrodynamic characteristics of the natively unfolded ... 24.6 Cytochrome c 11.7 4.05 Ribonuclease A 13.7 32.4 [41] Lysozyme 14.2 33.1 [41] Hemoglobin 15.5 33.5 Myoglobin 16.9 35.1 b-Lactoglobulin 18.5 37.8 [41] Chymotrypsinogen 25.7 45 [41] Carb...

Ngày tải lên: 08/03/2014, 16:20

... Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada; 2 Laboratory of Gynecologic Oncology, Department of Obstetric Gynecology and Reproductive Biology, Brigham ... Center, Boston, Massachusetts, USA; 3 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA; 4 Department of Immunology, University of Toronto, Toronto, Ontario, ....

Ngày tải lên: 08/03/2014, 23:20