Báo cáo y học: "iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations " pdf

... 2), reaction data (Table S2 in Additional data files 1 and 2), estimated thermodynamic data (Table S2 in Additional data files 1 and 2), model stoichiome- try in SBML format (Additional data file ... carboxylation reactions, phosphorylation reactions, CoA and ACP ligases, ABC transporters, and reac- tions utilizing ATP hydrolysis to drive an otherwise unfavora- ble action. We applied our n...

Ngày tải lên: 14/08/2014, 21:20

... tamponade has also been described [5]. Here we demonstrate a case of virtual suba- cute tamponade, modeled on the hemodynamic data reported by Reddy et al. [3] concerning a case of tampon- ade ... reveals key alterations during the cardiac cycle which may actively participate in the clinically observed features of tamponade. Under con- Circulatory Indices as a Function of Peri...

Ngày tải lên: 13/08/2014, 16:20

... which have lasted less than one month and 0.25 per day in longer partnerships. There is a constant per day probability of recovery of (1/ average duration of infection). A fraction of newly infected ... particularly among men, based on retrospective data collected by Natsal 2000. Recent data from the Health Protection Agency show that chlamydia diagnoses (and presumably treat-...

Ngày tải lên: 13/08/2014, 23:20

... largely unknown. SAMHD1 mutations are involved in Aicardi- Goutières syndrome (AGS), a genetic encephalopathy mimi cking congenital viral infection [13]. SAMHD1 was initially cloned from human DCs as an interferon ... and binding to RNA and non-SAM domain containing pro- teins. Given that SAMHD1 interferes with the accumula- tion of HIV-1 reverse transcripts, one can speculate that the SA...

Ngày tải lên: 13/08/2014, 01:21

... virus, another tumor had a monoclonally integrated viral concatemer, and two addi- tional tumors had an indeterminate integration pattern. For one tumor with a monoclonal integration pattern, ... Siguencia E: TTeemmppoorraarryy rreeggrreessssiioonn ooff MMeerrkkeell cceellll ccaarrcciinnoommaa mmeettaassttaasseess aafftteerr cceess ssaattiioonn ooff ccyycclloossppoorriinnee Transplantat...

Ngày tải lên: 14/08/2014, 08:21

... 21. Additional material Additional file 1 Genetic variation in sequenced genomes. Additional file 2 Clone library information. Additional file 3 Mate-pair variants and comparison with various data sets. Additional ... 42 M variants and comparison with vari- ous data sets. Additional file 7 Affymetrix 6.0 variants and comparison with various data sets. Additional file 8 Illumina 1 M variants...

Ngày tải lên: 09/08/2014, 20:22

... by limited ward and ICU bed availability introduce a higher percentage of critically ill patients awaiting ICU admission or transfer. Delays in ancillary testing and implementation of therapy ... may have a significant impact on clinical care [83]. NPPV is a viable option for emergency physicians managing patients with COPD, asthma, and pulmonary edema to avoid intubations, and im...

Ngày tải lên: 12/08/2014, 20:20

... smoking-cessation arms. Figure S5: Results of one-way sensitivity analyses on key parameter values showing change in base case incremental cost per QALY ratio. Table S1 - Model assumptions. List of abbreviations CI: ... McBride’ sstudywasalso Table 1 Data parameters used in model: description, base case estimate, range tested in one-way sensitivity analyses and sources Parameter desc...

Ngày tải lên: 13/08/2014, 11:22

... cross-reactivity with the antibody. Microarray analysis Total RNA was isolated from whole liver using the RNA STAT-60 Total RNA/mRNA Isolation Reagent according to the manufacturer's instructions ... of a 20 × lens with 0.5 NA, scanning stage, 3-color CCD camera and image anal- ysis software and database (Icoria Inc, Research Triangle Park, NC). Images were taken at 0.64 micron resol...

Ngày tải lên: 13/08/2014, 13:20

... an artifact of translation. Users should be particularly wary of genes used as hybridization controls. We re-analyzed our diabetic nephropathy sample data without probe transla- tion, using only ... nephropathy, Table 1 Sample data subjected to p value adjustment by Bonferroni correction or random-data simulation Actual diabetic nephropathy (downregulated) data Random-data simulation (10,...

Ngày tải lên: 14/08/2014, 14:22