Báo cáo y học: "A hidden reservoir of integrative elements i

Báo cáo y học: "A hidden reservoir of integrative elements is the major source of recently acquired foreign genes and ORFans in archaeal and bacterial genomes" pdf

... Biology 2009, 10:R65 Open Access 2009Cortezet al.Volume 10, Issue 6, Article R65 Research A hidden reservoir of integrative elements is the major source of recently acquired foreign genes and ORFans ... distribution, and reproduction in any medium, provided the original work is properly cited. Integrative elements and new genes& lt;p>A large-s...

Ngày tải lên : 14/08/2014, 21:20

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Báo cáo Y học: A single charged surface residue modiﬁes the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc

... Gly23 of birtoxin (Fig. 4). In ikitoxin the presence of Glu23 charge preceding the a-helix modifies the activity of this toxin in a unique way to result in reduced potency in mice. The C-termini ... each dose.Themicewereobservedfor24h,andeffectswereranked between 0 and 10, 0 being no effect and 10 being lethality. The inter- mediate ratings are based on the strength...

Ngày tải lên : 31/03/2014, 08:20

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Báo cáo y học: " A QTL on mouse chromosome 12 for the genetic variance in free-running circadian period between inbred strains of mice" potx

... 277). Expression analysis The expression analysis of whole brain had 29 probe-sets representing 14 of 15 known genes in the QTL, and 12 probe-sets representing 9 of the 12 predicted genes. In total, the chips ... for 85% of the genes in the AhR insert. The only gene in the QTL differentially expressed between B6 and D2 strains was Zfp277; it was also c...

Ngày tải lên : 10/08/2014, 09:20

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Báo cáo y học: " A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus" pptx

... selection of L74V is mainly associated with the use of didanosine. This study showed that the selection of L74V and L74I is controlled by two independent pathways and it is speculated that the resistance ... located in b3-b4 linkage group of finger sub-domain of RT are selected during treatment with several RT inhibitors, including didanosine, deoxycytidine, abacav...

Ngày tải lên : 11/08/2014, 21:21

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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx

... autoimmunity may be a secondary phenomenon induced following inflammation in the joints and may play a role in the persistence of the disease rather than in actual induction of arthritis [25,26]. In either ... collagen in the pathogenesis of RA, and long-term observations in large numbers of patients need to confirm the efficacy of CCII and determine the...

Ngày tải lên : 12/08/2014, 11:22

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Báo cáo y học: "A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy" pptx

... growth and apoptosis in the individual tissues indicate that the underlying mecha- nisms are not necessarily linked to each other. Despite the marked heterogeneity in the responsiveness of the different ... investiga- tion. CM and ARR carried out the LIFE/DEAD-assay and 2-pho- ton microscopy. PZ was involved in the design of the study, evaluation of the res...

Ngày tải lên : 12/08/2014, 15:20

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Báo cáo y học: "Diffusion-weighted magnetic resonance imaging for predicting the clinical outcome of comatose survivors after cardiac arrest: a cohort study" pptx

... jointly evaluated by two experienced neuroradiologists blinded to the patients’ clinical data. The brain injuries on DWI were categorised into four patterns on the basis of the injury region of ... outcome. ThedegreeofthechangesoftheDWIandtheADC signal intensity correlates with the severity of neuronal injury because modest changes reflect signs of ongoing lesions, and a s...

Ngày tải lên : 13/08/2014, 20:21

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Báo cáo y học: "A statistical method for predicting splice variants between two groups of samples using GeneChip® expression array data" pps

... con- sisted of ten tissue types. The robustness of their method depended on the number of the tissue types in the dataset. Thus, their method is not suitable for the comparison of two tissue types such ... [5]. For each probe, they calculated the difference in the fold change between each tissue type and the average of the remaining tissue types for the c...

Ngày tải lên : 13/08/2014, 23:20

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Báo cáo y học: " A 176 amino acid polypeptide derived from the mumps virus HN ectodomain shows immunological and biological properties similar to the HN protein" pdf

... of responding to MuV infection by inducing both the Th1 and Th2 immune specific responses and probably secretion of IgA in the mucosa. Discussion MuV HN protein is a highly relevant protein in ... proteins, an unglycosylated inner mem- brane or matrix protein (M) and three glycosylated envelope proteins, the fusion protein (F), the hemagglu- tinin-neuraminidase ( HN) p...

Ngày tải lên : 12/08/2014, 04:20

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Báo cáo y học: " A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames" ppt

... perturb the coding sequences of Rev and Env, one issue which we wished to investigate is whether the protein coding density of a region might constrain HIV-1 against developing muta- tions. The above ... for the ability of the more fit SIVtat2ex to emerge by correcting the stop codons which prevent the expression of the second coding exon of Tat. Our interpreta...

Ngày tải lên : 13/08/2014, 09:21

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