Báo cáo y học: " The WASP and WAVE family proteins Shusaku Kurisu and Tadaomi Takenawa" ppsx
Báo cáo y học: " The WASP and WAVE family proteins Shusaku Kurisu and Tadaomi Takenawa" ppsx
... biochemical activities of the WASP and WAVE family proteins, one of the main issues to be addressed is how WASPs and WAVEs and their associated proteins work together to shape various and complex actin ... of these proteins have SH3 domains that interact with WASP and WAVE proteins. Thus, membrane-deforming proteins recruit WASPs and WAVEs to the membrane...
Ngày tải lên: 14/08/2014, 21:20
Báo cáo y học: "The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unit"
... in the study cohort if their ICU stay was longer than one day in duration and they were documented to have exclusively 'normal' serum sodium level(s) as per the Cal- gary Laboratory ... data. These data were validated by nursing or respiratory therapy staff on at least an hourly basis by examining the degree to which they are representative and plausible. An HL-7 interface...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo Y học: The folding of dimeric cytoplasmic malate dehydrogenase Equilibrium and kinetic studies doc
... seen for the chemical cross-linking study (Fig. 9). The reactivation starts from zero activity at the first time point immediately after dilution of the denaturant. The rate and the yield of reactivation do ... the contribution of the other incorrectly folded dimers, which originate as a by- product of the major folding pathway, when monomers associate prematurely, before t...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx
... Pharmacy and Pharmacology, The University of Bath, UK Deacetoxycephalosporin C synthase (DAOCS) catalyses the oxidative ring expansion of penicillin N, the committed step in the biosynthesis ... analyses of the mutants suggested that no gross changes in structure had occurred compared to the wild- type enzyme. Enzyme assays Wild-type DAOCS and all mutants were assayed for thei...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf
... 11b-hydroxylase capacity of CYP11B2 mutants in relation to the wild-type enzyme, when incubated with 11-deoxycortisol. The 11b-hydroxylation of 11-deoxycortisol catalysed by the mutated proteins ... of CYP2 family members [35] and the B helix of the c rystal- lized P450s (Fig. 1). As the helices A, B, B¢,FandGofthe crystallized P450 proteins may contribute to the high su...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "The STRS (shortness of breath, tremulousness, racing heart, and sweating): A brief checklist for acute distress with panic-like autonomic indicators; development and factor structure" ppt
... has the potential to provide incremental validity over and above the PTSD criterion A2 items of the DSM-IV-TR. The easily interpret- able factor structure of the STRS confirms the adequacy of the ... 11.0. The types of dis- tressing incidents and their mean total scores on the orig- inal 14 items, and on the seven items on the STRS, and the ranks of mean total...
Ngày tải lên: 08/08/2014, 20:23
Báo cáo y học: "The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India" ppsx
... success, and obtained satisfactory employment, respectively. In the ability to live independently, 1 means never lived independently, 2 means occasionally lived independently, 3 means none of the ... health and nutrition was fulfilled by the family members and relatives of the patients. Discussion The present study has shown that the long-term outcome of schizophrenia in M...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "The Short Anxiety Screening Test in Greek: translation and validation" ppsx
... practical for use in everyday practice. According to the developers, the instrument can accurately and reliably identify symptoms of anxiety in older people even, and espe- cially, in the presence of ... procedures set by the Clinic of Social and Family Medicine at the University of Crete, written per- mission was obtained by the original developers and also the copyri...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus" potx
... which convert to high-affinity autoantibodies via somatic hypermutation. The aim of the present study was to determine whether the V H family repertoire and pattern of somatic hypermutation in germinal ... for 1 min and 72°C for 2 min, followed by one cycle at 72°C for 15 min. The Taq polymerase used was of high- fidelity quality (Expand Easy; Roche, Mannheim, Germany), which ha...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes" ppt
... fluid and serum samples. JLB and MJHN produced the recombinant IL-1F proteins. DM, GP, SB, PAG, MJHN and CG participated in the design of the study, data analysis, and drafting and reviewing of the ... purposes) receptor family, namely IL-18 receptor (IL-18R) and the IL-18R accessory protein [2]. Six new members of the IL-1 family were recently identified, primaril...
Ngày tải lên: 09/08/2014, 08:22