Báo cáo y học: " Translational disease interpretation with molecular networks" pps

... ppaatthhwwaayy aannaallyyssiiss PLoS ONE 2007, 22:: e425. 39. Taylor IW, Linding R, Warde-Farley D, Liu Y, Pesquita C, Faria D, Bull S, Pawson T, Morris Q, Wrana JL: DDyynnaammiicc mmoodduullaarriittyy ... importantly, they do not reveal the underlying molecular mechanisms accounting for the signatures. In such high-throughput experiments, the molecular mecha- nisms are typically anal...

Ngày tải lên: 14/08/2014, 21:20

... Biosystems, Foster City, California). Techni- cally satisfactory genotypes with sufficient heterozygosity for anal ysis were obtained for 197 S NPs [see Additional file 1]. In addition, a polymorphic ... J Psy chiatry 1967, 113:895–910. 3. Halberg F: Physiologic considerations underlying rhythmo- metry, with special reference to emotio nal illness. Sympo- sium on B iological Cycles and Ps...

Ngày tải lên: 10/08/2014, 09:20

... in mouse identifying potentially non-coding loci enriched with transcriptionally active histone modi- fi cations led to the discovery of several new lincRNAs. Using a guilt-by-association technique ... many challenges. Xiaoyu Chen (University of Washing- ton, Seattle, USA) described a dynamic Bayesian network model aimed at identifying transcription-factor-binding sites in yeast DNA fro...

Ngày tải lên: 09/08/2014, 20:22

... biological problems. In bioinformatics and systems biology the topics covered included the prediction of regulatory networks, microarray data analysis, and graph mining for structural biological ... to their biological function in a pathway or process, and in many cases modular structure and module components are highly conserved. Ying Xu (University of Georgia, Atlanta, USA) presented a ......

Ngày tải lên: 14/08/2014, 16:21

... discussed by Jayesh Pandey (Purdue University, West Lafayette, USA), who described a new method for measuring functional similarity using GO annotations and investigated how this similarity is correlated ... the method is (expectedly) reasonably accurate. Unfortunately, the performance of the approach drops off quickly when uncertainty about binding-site location is artificially intro- duced....

Ngày tải lên: 14/08/2014, 21:20

... study center: Tuulikki Sokka, Jyväskylä Central Hospital, Jyväskylä and Medcare Oy, Äänekoski, Fin- land, and Theodore Pincus, New York University Hospital for Joint Dis- eases, New York, NY, ... for physical inactivity, and 18% for obesity. Traditional risk factors except obesity and physical inactivity were significantly associated with CV morbidity. There was an association between any...

Ngày tải lên: 09/08/2014, 10:23

... and periodontal disease in PWS. A recent study that surveyed the orodental character- istics of 15 patients with PWS with early multidisciplin- ary follow-up at the university hospital reported ... asso- ciated with a variety of musculoskeletal abnormalities including scoliosis, short hands and feet, facial dysmor- phy, narrow hands with straight ulnar border, delayed bone age and j...

Ngày tải lên: 10/08/2014, 23:22

... citation purposes) points) was noticed, accompanying by lip swelling as well (Figure 3). Enteroclysis and colonoscopy plus ileoscopy showed active disease confined to the terminal ileum and the ... generally used to describe swelling of the orofacial area, mainly the lips, sec- ondary to an underlying granulomatous inflammatory process. It is a heterogeneous clinical condition that presents...

Ngày tải lên: 11/08/2014, 11:20

... cysts in patients with polycystic kidney disease are generally asymptomatic, but in a few patients, hepatomegal y from numerous large cysts may cause symptoms [1,4]. Treatment is usually only ... http://jmedicalcasereports.com/jmedicalcasereports/article/view/7442 Introduction Polycystic liver disease (PLD) is a common manifestation of polycystic kidney disease and is associated wi...

Ngày tải lên: 11/08/2014, 14:20

... dual-energ y X-ray a bsorptiometry (DXA) was assessed. The bone scans were performed by local radiologists and the results were reviewed by Synarc, Inc. (Portland, OR). The efficacy and safety analyses ... the efficacy and safety of MF-DPI 800 μg once daily in the evening and MF-DPI 400 μgtwicedailywithplacebo and with each other in subjects with COPD managed without ICS. Methods Study...

Ngày tải lên: 12/08/2014, 14:20