Báo cáo y học: "Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure" ppt

... changes in expression of the genes in the pathway are higher than that of the rest of the genes in the system). In the situation of low values of the CF factor, the Schematic of networks used to generate ... the goal is to compare the genes in the pathway of interest to the other genes in the system in terms of their associations with the...

Ngày tải lên: 14/08/2014, 21:20

... level of uncertainty about optimal therapy exists. The large number of different combinations chosen by physicians in the study by Mortensen et al. [10] is a clear indication that the therapeutic uncertainty ... second possibility, put forward by Mortensen et al. [10], is that their findings favouring macrolides are due to the immunomodulatory properties of this class of antib...

Ngày tải lên: 12/08/2014, 23:21

... have been previously reported [9,28-31], this type of footwear was not widely worn by patients in the current study. Additionally there are known factors relating to poor use of therapeutic footwear ... mobility [1]. The foot is often the first area of the body to be sys- tematically afflicted by RA [2-4]. Seventy-five percent (75%) of patients with RA report foot pain within...

Ngày tải lên: 10/08/2014, 21:24

... obtained from the patient for publicatio n of this case report and any accompany- ing images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Abbreviations CT: ... ventricle. To the best of our knowledge, there is no other case report of this combination of DCRV and calcification of the tri- cuspid valve. Consent Written in...

Ngày tải lên: 10/08/2014, 23:21

... volumes for acute lung injury and the acute respi- ratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000, 342:1301-1308. 11. Lim CM, Koh Y, Park W, Chin JY, Shim ... PaO 2 determined the closing pressure yielded open-lung PEEP values of the order of 18 to 20 cm H 2 O [4,8]. These values are similar to the ones reported by Gattinoni and col...

Ngày tải lên: 13/08/2014, 16:20

... anticipated. These factors significantly reduced the power of the study. Based on their findings, the authors estimate that more than 100 hospitals would be needed to show the 30% difference they sought. ... the MET system was left to the local hospital. No efforts were made by the investigators to reinforce MET concepts or to assess how well the MET concept was impl...

Ngày tải lên: 25/10/2012, 10:39

... or the management of patients have a sound grasp of at least the basics of statistical methods. Unfortunately, in practice this is often not true, with many relying on distant memories of poorly ... increasingly used in all fields of medicine but is often poorly understood and incorrectly applied. Critical Care is therefore launching a series of articles aimed at providing a...

Ngày tải lên: 25/10/2012, 10:45

... for the thermolability of MTHFR. Actually, the frequency of the mutated allele was quite high, depending on the ethnic group analyzed [18-21]. Some authors suggested that the homozygosity for ... 5-methyltetrahydrofolate as a carbon donor [6] . This donor is synthesized by the methylenetetrahydrofolate reductase (MTHFR) gene from 5,10-methylene-tetrahydrofolate [9,10]. Red...

Ngày tải lên: 03/11/2012, 09:49

... single threshold. The graph of the P K1 scores shown in Figure 1 illustrates the dif- ficulty - the slope of these scores is nearly linear, and as such the threshold (as shown by the hori- zontal line) ... solutions for all values of k from 1 N , and then determines the mean and standard deviation of the criterion function. Then, a score is computed for each value of...

Ngày tải lên: 22/02/2014, 02:20

... program to the baseline of always choosing the most frequent synonym according to the training corpus. But what are the 'correct' responses? Ideally, they should be chosen by a credible ... Ph.D. the- sis, University of Toronto. Yarowsky, David. 1992. Word-sense disambiguation using statistical models of Roget's categories trained on large cor- pora. I...

Ngày tải lên: 22/02/2014, 03:20