Báo cáo y học: "A whole-genome assembly of the domestic cow, Bos taurus" potx
... one assembly, and all other reads (at least three) confirmed the other assembly. The UMD2 assembly contains 10,636 instances of these apparent errors versus 30,750 in the BCM4 assembly. Thus, there ... library (Materials and methods), only a very limited amount of the assembly can be assigned to the Y chromosome. (It is worth noting here that the BCM4 assembly does...
Ngày tải lên: 14/08/2014, 21:20
... C-terminally to the CBM that play specific roles in activation of the receptor by these two cytokines. The ligand independent activation of the D5-GCSFR chimera occurs in both the absence and the presence ... copre- cipitation of gp130 with LIFR independently of the lysis buffer used for the disintegration of the cells (data not shown). Because of the high expre...
Ngày tải lên: 18/03/2014, 01:20
... lacking glycosylation [26]. In the first part of the present study similar end-point levels of transgenic and recombinant IL-1Ra were necessary to inhibit fully the response of synoviocytes to ... vivo concentrations of IL-1Ra in a sustained manner may be key to realizing the full therapeutic potential of this mater- ial. Gene delivery may offer the greatest chance of ea...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: " A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population" pps
... polyarthritis and systemic subgroups, the frequency of haplotype S01 did not differ statistically from that of healthy controls. The frequency of haplotype S01 was also significantly higher in the patients ... fre- quency of haplotype S01 of the IL18 gene is 37.9% and that of the S01/S01 diplotype configuration is 13.9% in the Japa- nese population. We also estimated...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc
... identification of new lymphoma cases based on consultation between rheumatology and oncology departments. Uncertainty regarding the size of the RA popula- tion evaluated may account for their very high ... relative risk of 7.4 for Hodgkin lymphoma. Sources of selection bias may include the use of hospitalization records for identification of populations. Other limitations in...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "A meta-analysis of the efficacy of fibromyalgia treatment according to level of care" pptx
... by the heterogeneity of the studies. Other variables that also improved outcome and were not biased by the heterogeneity of the studies, were younger age of the patients and shorter duration of ... homogeneity. In any case, the study points to moderate efficacy of any of the treatments described for fibromyalgia and similar efficacy in both primary and special- ised...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "A Rasch Analysis of the Manchester Foot Pain and Disability Index" pdf
... Table 1 shows the fit of the individual items. There was no misfit as measured by the item residuals or the chi-square fit sta- tistic in either of the subscales, after applying the Bonfer- roni ... disability of the sample. A mean person location of zero indicates that the items and the sample are perfectly targeted. The Person Separation Index (PSI) was considere...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "A critical review of the research literature on Six Sigma, Lean and StuderGroup''''s Hardwiring Excellence in the United States: the need to demonstrate and communicate the effectiveness of transformation strategies in healthcare" pdf
... validity. In spite of this strength, they still both share many of the same limitations and concerns, as noted above. In the case of the hand hygiene study [24], the authors do not specify what statistical ... Periodicals Directory and the publica- tion's website. These liberal criteria allowed for the inclu- sion of almost any study design, analytic strategy, outcome...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " A systematic review of the use of theory in the design of guideline dissemination and implementation strategies and interpretation of the results of rigorous evaluations" pps
... of all instances of the- ory use. Fourteen studies used 11 theories explicitly. Only two theories were used explicitly more than once. The PRECEDE theory was also the most commonly employed theory ... 2 of 6 choice of theory used and devel op a clear rationale of how the theory is proposed to operate within the study. Where possible, hypotheses deduced from the theory to...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: "A systematic review of the international published literature relating to quality of institutional care for people with longer term mental health problems" potx
... clarity of the research question or hypothesis, the type of methodology used [16] and relevance of the participants to the aims of the review); (4) data analysis (which included clarity of the ... based medicine; psychiatric rehabilitation; rehabilitat*; activities of daily living; art therapy; bibliotherapy; dance therapy; exercise therapy; music therapy; occupational...
Ngày tải lên: 11/08/2014, 17:20