Báo cáo y học: "TFCat: the curated catalog of mouse and human transcription factors" pdf

... directly involved in the activation or repression of the initiation of synthesis of RNA from a DNA template. Incorporating this standard, the union of the four sets yielded 3,230 putative mouse ... gene assay and/ or DNA-binding assay). A text summary of the experimental evi- dence was extracted and entered by the reviewer, along with the PubMed ID, the species...

Ngày tải lên: 14/08/2014, 21:20

... organogenesis in human embryos [6]. Yet other studies have analyzed the trans- criptomes of human oocytes, hESCs and human pre- implantation embryos (blastocysts) [7-9]. A few missing Geng and Oliver ... types and the formation of organs - become upregulated. During S12 to S14, structures such as the nervous system, the heart and the somites develop further; me...

Ngày tải lên: 09/08/2014, 20:22

... boundary condition, and the first and twenty-first segments are defined as the hot and cold regions, respectively. The coldest atom in the hot region and the hottest one in the cold region swap their ... Jing Shi* 1 , and Xinfeng Tang 2 1 Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education and School of Physics and Tech...

Ngày tải lên: 21/06/2014, 17:20

... residue for the final family is given in Fig. S1. Fig. 3A shows the family of 40 structures and Table 1 contains a summary of statistical data indica- ting the quality of the 40 models and the average ... syndrome, inflammatory dis- eases, pre-eclampsia or preterm labour, anxiety and depres- sion and a potentially great number of other disorders. We have previously des...

Ngày tải lên: 17/03/2014, 10:20

... with 2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k library or 1.0 lg of each plasmid of the overlapping lef library as described by Passarelli ... a portion of the origin of replication hr5. Two-hybrid yeast constructs were generated by PCR of each lef and insertion into the EcoRI and XhoI sites o...

Ngày tải lên: 23/03/2014, 21:20

... problem. Only low or nontoxic delivery systems could be used in humans. Therefore, we must test different delivery systems on RDOs, and try to lower their cytotoxity and improve their efficiency. FUTURE ... endosomes and be transported easily in the cytoplasm. Fourth, they should enter the nucleus easily. For transfection in vivo,this is one of the most important hurdles. Finally...

Ngày tải lên: 31/03/2014, 08:20

... deformity of bone contour [5]. The grade used for analysis was the higher of the two knees. We define generalized OA (GOA) by the hypothesis that OA found in the hand is an indicator of disease in other ... or the timing and choice of surgery could be improved. It is therefore very important to make progress in the study of imaging and biochemical markers currently...

Ngày tải lên: 09/08/2014, 01:23

... (RA). Pharmacology of the HMG-CoA reductase inhibitors The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG- CoA) reductase catalyses the conversion of HMG-CoA to mevalonic acid and is a rate-limiting ... inflammatory initiation and perpetuation via endothelial cells Effects of statins on endothelial cells have been studied primarily in the context of the endothelial dy...

Ngày tải lên: 09/08/2014, 06:22

... from human primary CD4+ lymphocytes [28] to find the number of H3K9ac tags that overlapped with the promoter regions (- 1 kb to +1 kb of the annotated TSSs) of the human orthologs of the mouse ... levels of the genes are from a matching human CD4+ lymphocyte microarray analysis [GEO:GSE10437]. The bar marks the median score, the edges of the boxes the...

Ngày tải lên: 09/08/2014, 20:20

... genes and is very rich in gene and segmental duplications. The origin of the Metazoa is a landmark event in the history of life and we are now taking critical steps in the under- standing of this ... (University of Montreal, Canada) and Inaki Ruiz-Trillo (University of Barcelona, Spain) highlighted studies on the evolutionary significance of the Choano fla...

Ngày tải lên: 09/08/2014, 20:21