Báo cáo y học: "Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes" pptx

... ↓ Degradation of dGMP to deoxyguanosine (dgn2) ↓ Degradation of L-lysine to crotonyl- CoA (lysine3) ↓ Degradation of tryptophane to 6- hydroxymelatonin (trp5) ↑ Biosynthesis of phosphatidylserine ... randomly picked pathways, all pathways, and pathways highly ranked in pathway selection. We are not able to associate (signifi- cantly) relevant pathways with any of th...

Ngày tải lên: 14/08/2014, 21:20

... parameters for early referral of AS patients by primary care physicians. Such parameters have to be relatively sensitive and specific for the disease in question, have to be easy to apply by the nonspecialist, ... and primary care physicians to refer to an early axial SpA clinic those patients who fulfilled one or more of the following criteria: fulfilling the clinical symptom...

Ngày tải lên: 09/08/2014, 01:22

... systemic lupus erythematosus (SLE) and is one of its major causes of death, an observation first made more than 20 years ago by Urowitz [1]. Coronary artery disease develops in 6–9% of SLE patients ... accounts for up to 36.4% of deaths in SLE. High rates of atherosclerotic vas- cular disease (ASVD) are particularly striking in young women with SLE, normally at low risk. The incid...

Ngày tải lên: 09/08/2014, 01:22

... Nakamura 4 1 Division of Motor Function Analysis, Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan 2 Department of Orthopaedic Surgery, ... 755-8611, Japan 4 Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan Corresponding author: Yasuaki Nakagawa, yana...

Ngày tải lên: 09/08/2014, 14:21

... and cDNA synthesized using the Applied Biosystems (Foster City, CA, USA) High-Capacity cDNA Reverse Transcription Kit. Typically, 2 μg of total RNA was added to a 20 μl first strand synthesis ... RACE adaptor. (c) Histogram depicting the distribution of polyadenylation positions of 3' expression tags, relative to the end of the L1. (d) Histogram depicting distribution of 5...

Ngày tải lên: 09/08/2014, 20:20

... suggesting that the MOF-catalyzed acetylation of histone 4, and subsequent unfolding effect of H4K16ac, is constrained by as yet unknown counter- acting factors (Figure 3a), conceivably by ones that ... chromatin transcription system showed that H4K16 acetylation does not automatically increase transcription by twofold, but by many-fold [50]. is strong activation potential of MOF ca...

Ngày tải lên: 09/08/2014, 20:22

... employees. To address this need, this study provides technical assis- tance to employers to identify high-quality depression products, referring to products that provide the type, intensity, and ... the impact of v alue-based (VB) and usual-care (UC) inter- vention on employer purchase of depression products; to identify mediators of intervention impact on employer purchase; a...

Ngày tải lên: 11/08/2014, 05:21

... therapy for systemic vasculitides for the initial induction of remis- sion [9,17]. Cyclophosphamide is a cytotoxic agent that achieves cytotoxic effects by alkylating DNA of rapidly proliferating ... collections of neutrophils. The pic- ture is typical of leukocytoclastic vasculitis. Figure 4 Left thenar punch biopsy pathology low power. Leukocy- toclastic vasculitis low power view o...

Ngày tải lên: 11/08/2014, 11:20

... aimed to clarify the optimum approach to the use of CT densitometry data for the assessment of alpha 1-antitrypsin (AAT) augmentation therapy on the progression of emphysema in AAT deficiency (AATD). Methods: ... "Density mask". An objective method to quantitate emphysema using computed tomography. Chest 1988, 94(4):782-787. 7. Parr DG, Stoel BC, Stolk J, Stockley RA: Va...

Ngày tải lên: 12/08/2014, 14:20

... plasma viscosity during an air pollution episode: a link to mortality? Lancet 1997, 349:1582-1587. 14. De Leon SF, Thurston GD, Ito K: Contribution of respiratory dis- ease to nonrespiratory mortality associations ... individuals with contributing respiratory conditions whose primary cause of death was circulatory were more affected by elevated levels of air pollution This role of...

Ngày tải lên: 12/08/2014, 15:20