Báo cáo y học: " Building bridges from ‘omics’ to cell biology" ppt

... http://genomebiology.com/2009/10/3/305 © 2009 BioMed Central Ltd A report from the Keystone Symposium on Molecular and Cellular Biology, ‘Omics Meets Cell Biology’, Breckenridge, Colorado, 25-30 January, 2009. A ... of variability, potentially due to heterogeneity in the cell population. But by controlling for cell morphology and density, biases in viral infection that had previous...

Ngày tải lên: 14/08/2014, 21:20

... intra- cellular infection, typically by a virus, by presenting peptides derived from cytoplasmic proteins to the TCR of CD8 + lineage T cells. Usually, the presence of a virally infected cell results ... nonclonally expanded polyclonal T cells, presumably reflecting the attrac- tion of the T cells by chemokines. Only this latter polyclonal population is markedly reduced by methotrexate...

Ngày tải lên: 09/08/2014, 01:22

... Leal C, Gómez-Beneyto M: Similar effect of family history of psychosis on Sylvian fissure size and auditory P200 amplitude in schizophrenic and bipolar subjects. Psychiatry Res 2001, 108:29-38. 25. ... of two years. The cohort of patients was divided into two groups according to the type of antipsychotic treatment. Only patients who took the same type of medication (conventional or atypi...

Ngày tải lên: 11/08/2014, 16:22

... strongly related to depression and least strongly to anxiety. Peer victimization and exclusion may also increase children's depressive symptoms [11,42-44] or even be causally related to the ... antecedents of depressive symptomatology at age 18: A prospective study. Journal of Youth and Adolescence 1991, 20:217-232. 21. Hay DF, Pawlby S: Prosocial development in relation to chil-...

Ngày tải lên: 13/08/2014, 18:21

... Pto. Martin discussed the means by which Pto resists the AvrPtoB E3 ligase activity and hypothesized that Pto actively inhibits ubiquitination (by phosphorylation of the ligase) or passively resists ... modules in the bacterial effector AvrPtoB from Pseudomonas syringae pv tomato DC3000 (Figure 1). The amino terminus (amino acids 1-307) of AvrPtoB interacts with the tomato Pto kinase, which...

Ngày tải lên: 14/08/2014, 08:21

... tumor cell biology. (a) In normal cells, the role of IDH1 and IDH2 enzymes is to convert isocitrate to α-ketoglutarate (α-KG), converting NADP+ to NADPH. The presence of α-KG regulates prolylhydroxylases ... and because α-KG is required by prolyl hydroxy- lases, enzymes that hydroxylate and promote the degra- dation of hypoxia-inducible factor 1α (HIF-1α), the intra- cellular levels o...

Ngày tải lên: 09/08/2014, 20:21

... study are enticing, several issues with the study design will need to be addressed when future investigators examine this issue. A classic case–control methodology should ideally be employed, ... Using estimates from direct and indirect charges, Seymour and colleagues found that total hospital costs increased by an average of nearly $34,000 for reintubated patients. Although the results o...

Ngày tải lên: 12/08/2014, 20:20

... previous study, two regions in the soybean genome com- prising approximately 0.5 Mb each surrounding the soybean cyst nematode resistance loci, rhg1 and Rhg4, were used to identify syntenic regions ... were referred to as synteny blocks 1a, 1b, and 2 [32]. The syntenic regions in barrel medic also totaled about 1 Mb, though they were scattered into smaller contigs. For example, synteny bl...

Ngày tải lên: 14/08/2014, 08:20

... development is often directed by the action of factors with extremely narrow cell- type specificity. Since appropriate genetic circuitry models are likely to depend upon cell- specific, or at least ... individually by brassinosteroid and auxin; for these genes, the two hormones appeared to act synergistically. Additionally, Nemhauser et al. [5] assayed transcriptional responses to br...

Ngày tải lên: 14/08/2014, 14:21

... mediates Myc autorepression and its tran- scriptional control at many loci. In this study the authors used the Gal4 UAS system to express ectopic dmyc in embryos and performed microarray analysis to ... cuticle hydrolase activity transferase activity ion transporter activity carrier activity structural constituent of cytoeskeleton microtubule motor activity nucleoside binding hydrolase ac...

Ngày tải lên: 14/08/2014, 20:22