Báo cáo y học: "Yeasts as models in evolutionary biology" ppt

... interesting case of systematic pleiotropy between sporulation and pseudohyphal growth in yeast. A survey of the two phenotypes in different wild and labora- tory yeast isolates indicates that a phenotypic ... of yeasts in studies of evolution and ecology. Yeasts as model systems permit an ideal marriage between theory and experiment, and the meeting concentrated on four core issues i...

Ngày tải lên: 14/08/2014, 21:20

... disease activity, it is nevertheless important in putting MPs center stage as disease markers and showing how the components in the blood can be mined in new and intriguing ways. Competing interests The ... that an increase in the level of secretory phospho- lipase A 2 could lead particle destruction via enzymatic diges- tion of membrane lipids. In that case, secretory phospholipa...

Ngày tải lên: 09/08/2014, 14:22

... Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant. Biochemistry 38, 11086–11092. 30. Franzen, S. (2002) Carbonmonoxy rebinding kinetics in h93g myoglobin: ... proximal cavity mutant of Hb has recently demonstrated the key role of the proximal histidine in the cooperativity of quaternary structure change in response to ligand binding [4]. Str...

Ngày tải lên: 08/03/2014, 16:20

... study of biopsy- proven GCA demonstrated no increase in carotid intimal thickness, so atherosclerosis alone does not explain the increased cardiovascular mortality seen in GCA [9]. Although Warrington ... and may contribute to the increased risk of PAD in isolated PMR. Conclusions The interesting findings of Warrington and colleagues add further weight to the association between vascula...

Ngày tải lên: 09/08/2014, 14:20

... (Kyoto Encyclopaedia of Genes and Genomes) ribosome pathway. RPS6 is also involved in the insulin signalling and the mTOR signalling pathway. MCM3 and VIM are involved in the pathways cell cycle and ... healthy blood donors. An example of a protein macroarray analyzed with serum is shown in Figure 2. The reactivity of each peptide clone was analyzed by visual evaluation utilizing the im...

Ngày tải lên: 12/08/2014, 14:20

... little consensus on what to do in terms of continuing treatment. HAART enables the immune system to function relatively normally and has demonstrable benefit in at least two areas impinging on ICU. Viral ... (Print ISSN 1364-8535; Online ISSN 1466-609X) Abstract The risks and benefits of stopping antiretroviral therapy in patients admitted to the ICU are largely unmeasured. In many ca...

Ngày tải lên: 12/08/2014, 18:21

... assay 8-isoprostane was assayed by an enzyme-linked immuno- sorbent assay (Cayman Chemical, Ann Arbor, MI). The lowest detection limit of the assay was 4.5 pg/ml and the intra and interassay correlation ... treatment in childhood asthma but measurement of airway inflammation using tradi- tional invasive procedures is not feasible in children. Bronchial biopsy is invasive and non-invasive...

Ngày tải lên: 12/08/2014, 18:21

... with ARDS, especially considering the constants for the slowly emptying compartments. All of the fitting methods tested in the present study assumed three basic hypotheses: the fast emp- tying of arteriolar ... spontaneously were instructed to maintain a relaxed expiratory pause of at least 10 s in order to minimize artifacts caused by respiratory variations in the intrathoracic pressur...

Ngày tải lên: 12/08/2014, 20:21

... during the past two decades. Interestingly, critical illness has the potential to become a key testing ground and field of application for these emerging modeling techniques, given the increasing ... accomplished by a Commentary Modeling longitudinal data in acute illness Gilles Clermont CIRM (Center for Inflammation and Regenerative Modeling), Clinical Research, Investigation and Systems M...

Ngày tải lên: 13/08/2014, 08:20

... length of stay in a country of asylum has increased from 9 years in 1993 to 17 years in 2003. In most instances, refugees stay in host countries well past the emergency phase of the initial crisis ... when assessed on a per capita basis. The needs of the host populations were similarly constrained by their baseline meagre living conditions and very low economic indicators. In gene...

Ngày tải lên: 13/08/2014, 15:21