Báo cáo y học: "Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays" potx

... [4-6]). Recently, there has been a flourish of transcript mapping using genome tiling arrays capable of measuring nearly all nonredundant sequences in the genome, far beyond the capa- bility of previous ... data can The Arabidopsis tiling arrays portray several interesting classes of circadian behavior in the genomeFigure 1 The Arabidopsis tiling arrays portray...

Ngày tải lên: 14/08/2014, 21:20

... available of 94% of the operating theatre productiv- ity teams, 82% of the pressure ulcer teams, 78% of the waiting list teams, 50% of the wound infection teams, 41% of the medication safety teams, ... in 61% of all teams in the study sample. It is very likely that the positive results are overrepresented, particularly because the absence of monitoring data may...

Ngày tải lên: 11/08/2014, 05:21

... although the HGGG loop was a critical structural element for the catalytic efficiency of the enzyme, the cold adaptation of the enzyme could not be attributed to the presence of the Gly cluster ... G261A/ Y2 69A designed on the basis of side-chain packing criteria from a modelled structure of the enzyme resulted in restor- ation of the energy of activation to...

Ngày tải lên: 22/02/2014, 04:20

... of the protons in the protein binding site were automatically assigned by FLEXX . In cases of ambiguities (hydrogens of the h ydroxyl groups, the N-bound proton of the h istidine side chain) they ... analysis they determined the binding free energy, enthalpy and entropy of the ubiquinone to the Q B -site. Methyl substituted 1,4-naphthoquinones have gained substantial...

Ngày tải lên: 31/03/2014, 21:21

... Two of the authors of the manuscript (MW and CD) are employees of Talecris and participated in the design of the study, in the col- lection, analysis and interpretation of data (CD was the statistician ... to clarify the optimum approach to the use of CT densitometry data for the assessment of alpha 1-antitrypsin (AAT) augmentation therapy on the progression...

Ngày tải lên: 12/08/2014, 14:20

... is, they have the property of self- renewal. Second, when introduced into a host blastocyst they contribute to all tissues and even the germ cells of the result- ing chimeric animal: they have the ... further functional analysis. Ivanova et al. [2] then assessed the effects of the loss of each of these proteins on the ES cells’ capacity for self-renewal. To do this th...

Ngày tải lên: 14/08/2014, 17:22

... replaced by the concordances of the instances of w1. Regarding the interpretation of the results, if the ratio between s3 and s4 should turn out to be similar to the ratio between s1 and s2, then the influence ... (63) by a factor of 3.2. Note that the increase of incorrect cases is probably mostly an artefact of the sparse- data-problem as the number of unde...

Ngày tải lên: 08/03/2014, 21:20

... residue for the final family is given in Fig. S1. Fig. 3A shows the family of 40 structures and Table 1 contains a summary of statistical data indica- ting the quality of the 40 models and the average ... residues. Analysis of the distribution of the electrostatic potential on the surface of the molecule reveals the ampiphilic character of the helix (Fig. 4A...

Ngày tải lên: 17/03/2014, 10:20

... with 2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k library or 1.0 lg of each plasmid of the overlapping lef library as described by Passarelli ... by insertion of PCR products into the BglII and PspAI sites of plasmid phsp70HAHisVI+ containing the 5¢ terminal amino acid sequence RYPYDVPDYARA. The sequenc...

Ngày tải lên: 23/03/2014, 21:20

... easily in the cytoplasm. Fourth, they should enter the nucleus easily. For transfection in vivo,this is one of the most important hurdles. Finally, cytotoxity is another major problem. Only low ... but also improves the relative efficiency of RDOs. However, these modified delivery systems are not ideal, because of instability in serum or toxicity to cells. THE MAJOR DELIVERY BAR...

Ngày tải lên: 31/03/2014, 08:20