Báo cáo y học: " Identification of novel transcripts with differential dorso-ventral expression in Xenopus gastrula using serial analysis of gene expression" pptx

... a list of at least 86 novel transcripts with differential expression in the dorso-ventral axis. Interest- ingly, the expression of three transcripts was independent of -catenin signaling. To ... differential expression along the dorso-ventral axis. Interestingly, the expression of some novel transcripts was independent of -catenin. Conclusions: Our SA...

Ngày tải lên: 14/08/2014, 21:20

... protein profiling of patients with chronic liver diseases. Hepa- tology. 2005; 41:40-47. 28. Cho WC, Yip TT, Ngan RK, Yip TT, Podust VN. ProteinChip array profiling for identification of disease- ... tool for integrating separation and analysis of complex mixtures of proteins. Captured proteins are then analyzed by TOF-MS, generating a spectral map depicting approximations...

Ngày tải lên: 25/10/2012, 11:18

... development of RA. The combination gave a specificity of 100% for diagnosing RA. Introduction A single nucleotide polymorphism in the PTPN22 gene encod- ing the lymphoid protein tyrosine phosphatase (Lyp) ... from arginine into tryptophan. This amino acid change disrupts the binding of Lyp to an intracellular kinase, Csk, which can then no longer inactivate another kinase, Lck, that...

Ngày tải lên: 09/08/2014, 07:20

... analyzed within ZINBA using 250-bp windows and an additional offsets of 125 bp. The set of covariates and all possible pair-wise and three-way interactions were evaluated using the BIC, with ... ChIP-seq in that it is an antibody-free method that recovers DNA fragments that are relatively resistant to formaldehyde crosslinking to proteins. The crosslinking profile of chromatin i...

Ngày tải lên: 09/08/2014, 23:20

... sternal dehiscence, depending on the fractures of some right ribs, occurred again after a week. After having implanted a polypropylene patch to avoid injuries to the underlying heart, we have initially used the vacuum ... complication after cardiac surgery. Obesity, osteoporosis, chronic obstructive pulmonary disease (COPD), diabetes, intake of corticosteroids and off-midline sternotomy a...

Ngày tải lên: 10/08/2014, 09:22

... It may account for the high variability in effective anti-coagulant doses of aspirin in the population (2, 3). Increased hydrolysis of circulating aspirin, pharmacokinetically corresponding ... two distinct aspirin hydrolysis pathways act: a spontaneous pH-dependent hydrolysis and an en- zymatic hydrolysis by plasma/serum and erythrocyte esterases (6). The circulating aspirin este...

Ngày tải lên: 26/10/2012, 09:39

... each inhibit proinflammatory cytokine induction of MMP-1 and MMP-13 gene expression. In this study, we address the inhib- itory effects of adding both ligands on MMP-1 and MMP-13 expression in ... MMP-13 with a polyclonal MMP-13 antibody generously provided by Peter Mitchell (Pfizer Inc, New York, NY, USA). Protein bands were visualized by incubation with a goat anti-rabbit s...

Ngày tải lên: 09/08/2014, 13:22

... largely agree with hotspots inferred by LD-based methods [15]. Next, our method looks for single-locus cis-association of the variation in hotspot strength with genetic poly- morphism in relatively ... formation. Chowdhury et al. [34] identified six genetic loci asso- ciated with recombination phenotype, including one in the RNF212 gene, and also found differences in sequence...

Ngày tải lên: 09/08/2014, 22:23

... phenomena using 8- color cytokine flow cytometry, and tested the hypothesis that these two findings were causally related. We analyzed cytokine profiles and memory/effector phenotypes of HIV-specific ... identically to the PBMC samples, except that all stains (including cytokines) were added during the "surface staining" step. Sample acquisition and analysis Flow cytometry was...

Ngày tải lên: 10/08/2014, 05:20

... of statins to operat ive risk. However the absence of statin treatment was associated with an increase in mortality in the subset of high risk patients with an esti- mated risk of mortality of ... datab ase analysis was used to examine the role of preoperative statin use in hospital mortality, for patients undergoing isolated coronary artery bypass grafting (CABG.) Met...

Ngày tải lên: 10/08/2014, 10:20